What are monoclonal antibodies – and can they treat Covid-19?
For more than 30 years, monoclonal antibodies have transformed the way we treat many diseases. Researchers think they are also one of the most promising treatments for Covid-19. Here's why.
- 7 October 2020
- 9 min read
- by Wellcome
1. What are monoclonal antibodies?
Monoclonal antibodies are a class of medicines that have transformed the way we prevent and treat diseases, from cancer and diseases of the immune system, to childhood viral infections.
They are not chemical compounds, as most drugs are. They are based on natural antibodies – which are proteins that the body produces to defend itself against disease – but are created in the lab and mass-produced in factories. This is why they’re sometimes called ‘designer antibodies’ – they are tailor-made to the disease they treat.
The first monoclonal antibody product was licensed more than 30 years ago. Since then, millions of people have benefitted from more than 100 such treatments. Around 50 of these were brought to market in the past six years alone.
This is one of the fastest-growing fields in biomedical research, and an increasingly important segment of the pharmaceutical market – last year, seven of the top 10 best-selling drugs were monoclonal antibodies.
2. How do they work?
Antibodies are proteins produced by our immune system and are one of the main ways the body defends itself against diseases.
They work by binding to their specific targets – for example viruses, bacteria or cancerous cells – and making them harmless. They block the action of the target, or they flag it as foreign so that other parts of our immune system can clear the ‘invaders’ away.
Monoclonal antibodies work in the same way too.
They bind to their specific target, without harming anything else in their way. This target is not always a ‘foreign intruder’, like a virus. Antibodies can be designed to attach to different molecules in the body, for example, to turn down the immune response when it overreacts; this phenomenon, which also happens with some Covid-19 patients, is called a ‘cytokine storm’.
Due to their numerous applications, monoclonal antibodies have been safely and effectively used to treat a growing number of diseases, some of which were difficult to treat in the past.
3. How are they made?
Making monoclonal antibodies is complex and expensive.
First, scientists extract the relevant antibodies from human blood. Then they replicate and manufacture them in large quantities.
Most monoclonal antibodies are produced in Chinese hamster ovary cells which are typically grown in large bioreactors for around 10 to 15 days. The resulting antibodies are then purified and packaged so they can be easily administered.
This whole process takes a long time and uses costly materials. Some estimate that the cost of producing one gram of marketed monoclonal antibodies is between $95 and $200; this doesn’t include the costs of research and development, or packaging, delivering and administering the medicine. The costs are even higher for start-up companies.
Manufacturers are looking into ways to reduce production costs, for example through novel technologies and using alternatives to hamster cells (such as algae, yeast and plants) that would change the way these drugs are made.
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4. What diseases are they used for?
The majority of the monoclonal antibodies on the market are for noncommunicable diseases, such as autoimmune diseases, like rheumatoid arthritis and cancer.
In the past few decades, cancer immunotherapies have saved the lives of millions of people around the world. Monoclonal antibodies have transformed the way we treat multiple cancers, including breast cancer, for which the drug Herceptin has been a game changer.
Out of more than 100 licensed monoclonal antibodies, only seven are for treating and preventing infectious diseases – though many more are in development, including candidates for SARS-CoV-2, the virus that causes Covid-19.
Monoclonal antibodies could have a huge impact on the way we treat and prevent infectious diseases. And there are already promising signs.
Two experimental antibody therapies against Ebola are being used to great effect as part of an emergency access programme in the Democratic Republic of the Congo.
And several antibodies that can act against different strains of HIV are also in development.
5. Can monoclonal antibodies treat Covid-19?
For the past 30 years, monoclonal antibodies have transformed the way we treat various diseases – they proved to be more effective, better tolerated and easier to deliver than other treatments.
Researchers are optimistic that monoclonal antibodies could help prevent and treat early infections of Covid-19 too.
Some of the advantages they offer are:
- they can specifically target the SARS-CoV-2 virus because they originate in the blood of people who have recovered from Covid-19; this would potentially make them more effective than other drugs.
- they can be rapidly isolated and manufactured – since the pandemic started, more than 70 monoclonal antibody products for Covid-19 are now in development.
- they can provide rapid protection against infection – once administered, monoclonal antibodies enter the bloodstream straight away and offer immediate protection for a few weeks or months. Vaccines take a few weeks to have an effect, but usually provide long-term protection. This is why researchers are optimistic that monoclonal antibodies could complement vaccines in helping to contain the pandemic.
- they have the potential to treat infected patients or prevent infection in all individuals, including the elderly and young children, and immunocompromised people – some of whom can’t receive a vaccine, or for whom vaccines don’t always work as well.
6. How many monoclonal antibodies for Covid-19 are in development?
Since the start of the pandemic researchers have been rapidly evaluating existing drugs and developing new treatments – including monoclonal antibodies – to treat Covid-19 patients.
Several monoclonal antibodies that are licensed or in development for other diseases are in clinical trials to see if they have an effect on Covid-19 patients. One of these is adalimumab, used to treat arthritis and Crohn's disease; the University of Oxford recently launched a trial to look at its potential to treat people in care homes, funded by the COVID-19 Therapeutics Accelerator.
Researchers have also been rapidly identifying monoclonal antibodies that specifically target SARS-CoV-2. More than 70 such products are already in development.
The pharmaceutical company Lilly, in collaboration with AbCellera, launched the first human study of a potential Covid-19 antibody treatment in May-June this year. Other safety clinical trials followed, including studies by AstraZeneca, Celltrion and Regeneron.
7. When will Covid-19 monoclonal antibodies be available, and who will get them?
The speed of research into Covid-19 treatments has been unprecedented.
One of the advantages of monoclonal antibodies is that clinical trials can happen even more rapidly; because these are based on natural antibodies, not chemical compounds, safety trials take less time.
In less than four months since the start of their clinical trials for Covid-19 antibody-products, Lilly and Regeneron published early results showing encouraging signs. Results from other clinical studies are expected later this autumn.
Knowing if any of these antibody treatments are safe and effective for treating or preventing Covid-19 is only the first step.
Making them available to patients will depend on many other things, such as manufacturing capacity – how quickly large quantities of the effective treatment can be made. It will also depend on price – who will be able to afford to buy them.
The ACT-Accelerator is a ground breaking collaboration created for exactly this purpose – to make sure that any Covid-19 treatments, vaccines and tests will be accessible to those who need them most, across the world, not only in the countries that can afford to pay the highest costs.
8. Are monoclonal antibodies expensive?
Monoclonal antibodies are more complex and expensive to produce than other types of drugs. This makes them some of the most expensive drugs in the world, unaffordable for most of the world’s population.
The median price for monoclonal antibody treatments in the US ranges from $15,000 to $200,000 a year. Although drug prices vary greatly worldwide, companies that market many of these treatments focus primarily on high-income countries, where prices are the highest.
As a result, almost 80 per cent of monoclonal antibodies are sold in the US, Canada and Europe. That could change.
Biosimilar products are one way to reduce production costs and make these innovative treatments cheaper. Once the original monoclonal antibody product is off patent, companies can create similar, but cheaper products. An example is Canmab – a biosimilar version of the breast cancer drug Herceptin – which sells for $100–$200 per dose in India. This is significantly less than the $1,800 price per dose in the US.
Another way companies can make monoclonal antibodies cheaper is by introducing second brands which can only be sold in low- and middle-income countries. One example is Herclon, another brand that Herceptin is sold as.
9. Are they available everywhere?
Antibody treatments are not widely available, particularly in low- and middle-income countries. Although 85 per cent of the global population live in these countries, they account for less than 20 per cent of the global sales of monoclonal antibodies.
Very few licensed monoclonal antibodies are even registered in low- and middle-income countries.
That’s true even for some infectious diseases that affect developing countries more than the rest of the world. For example, 99 per cent of deaths caused by respiratory syncytial virus are in low- and middle-income countries. But 99 per cent of the sales of Synagis, an antibody-based preventive, are in the US and Europe.
And the few monoclonal antibodies that are registered in low- and middle-income countries are often unavailable through the public health system, so unaffordable to most people.
India is one of the few middle-income countries that stands out, mainly because of its local manufacturing capacity – it has more than 100 companies that make biosimilar products. Still, people in India only have access to a fraction of the antibody products from the US market.
10. What will it take to make monoclonal antibodies more available and affordable?
Millions of people around the world could benefit from existing monoclonal antibody treatments and those in development – including the ones for Covid-19, which could help bring the pandemic to an end.
These innovative products are not currently accessible for most of the world’s population. That could change if governments, the bio-pharmaceutical industry, global health organisations and funders work together.
Some of the things they could do to make monoclonal antibodies more available across the world include:
- spreading the word about how valuable antibody therapies can be for treating a range of diseases, and advocate for greater access
- making it easier to register antibody therapies in low- and middle-income countries
- developing guidelines for monoclonal antibodies to make sure that these products are designed with the needs of local populations in mind.
To make monoclonal antibodies more affordable, they should:
- invest in innovative technologies that could lower production costs
- create new business models that enable different market approaches in low-, middle- and high-income countries
- establish collaborations between public, private and philanthropic organisations to focus on the needs of the developing countries.
Original article
This article is republished from Wellcome. Read the article here.
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Omicron: why the WHO designated it a variant of concern
Not much data, but lessons have been learned from the slow response to delta.
29 November 2021
Routine vaccines, extraordinary impact: Measles
Measles is one of the world’s most contagious viruses. It can impair sight, hearing and cause brain inflammation and pneumonia. But even though it can be prevented by a vaccine, outbreaks in unvaccinated children continue to erupt even in the…
29 November 2021
Journalists fighting the pandemic: Cameroon's COVID-19 unsung heroes
The media men and women in the country are doing their all to reverse this phenomenon.
26 November 2021
How to gauge a plague: new analysis sheds light on the meaning of a 6th century pandemic
Disease outbreaks have shaped the world. But how much? New thinking on an early medieval pandemic takes on “plague sceptics” to show that we likely underestimated the impact of the first cross-continental assault of bubonic plague.
26 November 2021
The Future of Global Pandemic Security: Navigating shifting landscapes – a Gavi White Paper
The COVID-19 pandemic has demonstrated how ill-prepared health systems and societies are in the face of pandemic shocks and their protracted impact. Now, as global attention begins to shift towards improving the way we prevent and respond to…
26 November 2021
What do we know about the new B.1.1.529 coronavirus variant and should we be worried?
The variant was first detected in Botswana and contains a high number of mutations associated with increased immune evasion.
25 November 2021
Maternal vaccine urgently needed to protect babies against Strep B
A new report reveals the devastating global impact of Group B streptococcus, but suggests vaccinating against it could be highly cost-effective – if an effective vaccine can be developed.
25 November 2021
Study: government vaccine spending increases since 2000
A comprehensive analysis of vaccine spending shows that while lower-income country governments take on the bulk of financing, they need to mobilise greater resources for immunisation.
24 November 2021
COVID-19 and the impact on part time jobs
The loss of jobs during the pandemic was experienced almost exclusively among part-time jobs. Research shows it is likely that demand for workers in hard-hit sectors will start to come back, writes economist Jonathan Wadsworth. However, the…
24 November 2021
COVAX slot swapping: Explained
Switzerland has just become the first country to trade places with COVAX in manufacturers’ supply queues, making one million doses of Moderna’s COVID-19 vaccine available to the Facility. But what is slot swapping and why is it necessary?
23 November 2021
Immune to COVID-19: Why some people test negative when everyone around them is testing positive
Researchers are closing in on why some people are apparently more resistant to COVID-19 infection.
23 November 2021
Why COVID-19 Misinformation Works
The rampant spread of false information about the coronavirus has been attributed to politicians who have promoted remedies ranging from anti-malarial drugs to herbal drinks. But how humans process knowledge has an important role to play in…
22 November 2021
South Sudan launches mandatory testing and vaccination
There are differing views on whether mandatory testing and vaccinations will improve COVID-19 vaccine uptake.
22 November 2021
How Peru became the country with the highest COVID death rate in the world
The country moved quickly to contain the virus, but its health system struggled to look after those who got sick.
22 November 2021
COVID-19 vaccines: Nepal leaves no people with disability behind
"Leave no one behind" has been one of the core pledges of the SDG 2030 agenda. In light of the COVID-19 situation, it is vital to consider the plight faced by people with disability. Nepal has lessons for us all.
19 November 2021
Young and ethnic minority workers were hardest hit at the start of COVID, but not anymore
The two groups bounced back more quickly in the jobs market than certain other groups, although they may still experience lasting consequences.
18 November 2021
Hospital waste, not masks, are plastic scourge of pandemic: Study
A new study has found that 26,000 metric tons of pandemic-related plastic waste has been released into the world’s oceans since the start of the COVID-19 pandemic in January 2020.
18 November 2021
Traditional governance systems help turn the tide against COVID-19 in Kenya
A century-old system of governance has helped keep their land plentiful and their villages peaceful. Now elders in Isiolo County, central Kenya, are using the system to keep their villages free of COVID-19.
18 November 2021
Luciferase is a useful tool in medicine and has nothing to do with Satan.
17 November 2021
Is this the great vaccine-mandate resignation that wasn’t?
COVID-19 vaccine mandates have spurred protests and resignations. But the evidence so far points to marginal workforce losses. Evidence also suggests that mandates keep people safe and save lives.
16 November 2021
My shampoo stinks of vomit: How COVID-19 can mess up your sense of smell
Increasingly, people who are recovering from COVID-19 are reporting a distorted perception of odours, also known as parosmia.
16 November 2021
Why having bad oral health could raise the risk of COVID
Badly controlled bacteria in the mouth pose multiple risks.
16 November 2021
Kenya’s weak link in the fight against COVID-19
On 7 October Kenya launched an ambitious campaign to vaccinate over a million operators in the public transport sector.
15 November 2021
How disease has stimulated cultural change
Laws and rituals surrounding disease have been part of everyday life for millennia. Here's why that's important.
15 November 2021
History’s Seven Deadliest Plagues
SARS-CoV-2 has officially claimed 5 million lives, but credible estimates place the pandemic’s true death toll closer to 17 million. Either count secures COVID-19’s position on our list of history’s deadliest plagues.
12 November 2021
What pneumonia can teach us about COVID-19
COVID-19 still has many unknowns, but hope lies in what we already know about preventing and treating pneumonia.
12 November 2021
Two-strike Ebola vaccine enters human trials
The vaccine, which is based on the Oxford/AstraZeneca COVID-19 vaccine, is designed to target both the Zaire and Sudan species of Ebola virus.
12 November 2021
India’s pneumococcal vaccine rollout will save 50,000 children a year
Pneumococcal Conjugate Vaccine has now been introduced in every state in India, meaning this lifesaver will be available to every child in the country.
11 November 2021
Investments in Disease Surveillance Support Kenya’s Response to COVID-19
In a conversation with Maria Deloria Knoll, PhD, IVAC’s Director of Epidemiology, Dr. Kagucia shared how Gavi-supported activities facilitated Kenya’s COVID-19 response by expanding capacity, testing, and partnerships.
11 November 2021
Lagos steps up the fight against COVID-19
Lagod – the epicentre of COVID-19 in Nigeria – is ramping up its vaccination campaign, with committed leaders and ambitious targets.
10 November 2021
Can vaccines unlock access to health care?
Zero-dose children who never receive a single vaccine are also more likely to miss out on crucial primary health care services.
10 November 2021
Discoveries from vaccine implementation
In episode 8 of the Global Health Matters podcast, we spoke to Professor Margaret Gyapong of the University of Health and Allied Sciences in Ghana and Dr Lee Hampton of Gavi, the Vaccine Alliance. These experts shared their views on how…
9 November 2021
Sickness and survival in pre-COVID-19 Nepal
A gripping documentary about a family's struggle with the emotional and financial consequences of severe pneumonia.
9 November 2021
Nose sprays, needle-free patches, durable immunity: towards the next generation of COVID vaccines
The development of COVID vaccines has already been explosive. There are more innovations on the way.
9 November 2021
Benin youth turn to technology to fight COVID-19
In Benin, young people are spearheading a new digital fight against the pandemic.
8 November 2021
White-tailed deer found to be huge reservoir of coronavirus infection
In a sample of white-tailed deer, 80% were found to have an active COVID infection.
8 November 2021
Q&A: Dr Collins Tabu, Kenya’s immunisation chief, discusses the COVID-19 vaccine roll-out
Dr Collins Tabu, Head of Kenya's National Vaccines and Immunisation Program, is on a mission to vaccinate at least half of the adult population against COVID-19 by the end of the year. #VaccinesWork spoke to him to see how they plan to do it.
8 November 2021
HPV vaccine cuts cervical cancer cases by nearly 90%
Real world data from the UK shows the value of vaccinating girls against human papilloma virus (HPV) when they are 12 to 13 years of age.
5 November 2021
In February 2021, Côte d’Ivoire’s efforts to vaccinate its population in order to save lives and stem the spread of the coronavirus were being stymied by a wave of misinformation and a low level of public acceptance of the vaccine.
5 November 2021
Vaccine rollout steps up a gear in Sierra Leone
Just 5.5% of Sierra Leoneans have had their first COVID-19 vaccination. With a target to reach at least 80% by December the campaign, with support from COVAX, is ramping up.
5 November 2021
Dr Thomas Tu has an intimate relationship with the virus he’s devoted his life to studying, having been diagnosed with chronic hepatitis B at the age of 14. He discusses the stigma associated with the disease and the future of treating it.
4 November 2021
Five crucial years, one unprecedented new pandemic and 324 million children immunised
Even with the adversities and challenges of the COVID-19 pandemic through 2020, Gavi maintained unyielding focus on leaving no one behind.
4 November 2021
COVID-19 vaccinations help restore family links in Kenya’s prisons
Inmates in Kenya’s prison system have been banned from seeing family members for over a year and a half. A vaccination campaign.
4 November 2021
Routine vaccines, extraordinary impact: Hepatitis B
Hepatitis B kills more people each year than AIDS-related illnesses, yet an effective vaccine exists. Ensuring every child has access to it is crucial to fighting back.
3 November 2021
Routine vaccines, extraordinary impact: Haemophilus influenzae type b (Hib)
Before immunisation for Hib became routine, it was one of the biggest killers of children under five and the main cause of meningitis. High vaccine coverage is essential to keep that threat at bay, especially given rising antimicrobial resistance…
3 November 2021
Protecting prisoners in Malawi
Malawi prisoners are at higher risk of getting COVID 19; vaccines are helping to contain the spread.
2 November 2021
COVID could wreak havoc on gorillas, but they social distance better than we do
Endangered mountain gorillas in Rwanda’s famous Volcanoes National Park could face “population collapse” within 50 years if some of them contract COVID-19, new research suggests.
2 November 2021
COVID-19 wreaks havoc on the Kenyan entertainment industry
While there are those who have thrived, for most entertainers in Kenya COVID-19 came close to decimating the sector.
2 November 2021
Q&A: Designing a shock-proof health system
How do we ensure resilient health systems and immunisation programmes that can bounce back from future health threats? In this Q&A with Gustavo Correa, Gavi’s Senior Manager for Data systems and Information, and Josh Wunderlich, Gavi…
1 November 2021
Doctors, scientists or politicians: who are you most likely to trust after the pandemic?
Doctors are rated as trustworthy by almost two-thirds of people, according to the Ipsos Global Trustworthiness Index 2021. Scientists came in second, at 61% and teachers third, at 55%. How to restore trust is a key and growing theme for…
1 November 2021
Without global vaccination, all COVID immunity is at risk
A year from now, instead of potentially entering the pandemic endgame, we could find ourselves at the start of a new and perpetual cycle of revaccination or boosters for people who have already previously been protected.
1 November 2021
The Test of Pandemic Preparedness
The COVID-19 pandemic is the product of a globalized, interconnected world. Without new mechanisms that offer truly global approaches to crisis management and prevention, the experience of the past 18 months is likely to be repeated, with…
29 October 2021
How long after I get COVID-19 will I test negative?
Testing positive for COVID-19 even without symptoms can be disruptive to life, but how long should we expect to test positive for?
29 October 2021
COVAX can make even more of a difference if governments stop hoarding vaccine doses and allow the free flow of these crucial supplies.
29 October 2021
No one is safe until everyone is safe
To end the pandemic, the virus needs to be stamped out simultaneously across the world, but government hoarding and export restrictions are getting in the way of making this happen.
28 October 2021
What COVID-19 is teaching us about human milk and antibodies
Dr Rebecca Powell is on a quest to understand the immune response to infection and vaccination in breastmilk, in the hope of designing maternal vaccines to boost babies’ protection against disease.
28 October 2021
The walls speak for the vulnerable in Luanda
Oksanna Dias has been using street art to draw attention to the challenges of the women of Luanda.
28 October 2021
Injectable rotavirus vaccines – what value could they bring?
Currently in advanced development, these next-generation rotavirus vaccines may address key barriers to vaccine uptake and access.
27 October 2021
Routine vaccines, extraordinary impact: Tetanus
The disease can kill one in five people infected, yet an effective vaccine exists. Routine tetanus immunisation saves the lives of thousands of newborns every year.
27 October 2021
Religious leaders join chorus of support for vaccination in Nigeria
Initially silent, respected religious leaders in Nigeria are beginning to make their voices heard in support of COVID-19 vaccines.
26 October 2021
Vaccine Ambassadors: The race to vaccinate Cameroon’s school communities
Cameroon is considering taking COVID-19 vaccines to schools amid a rise in the number of new cases.
26 October 2021
Towards universal coverage of maternal health services in Tajikistan
Nozanin is a secondary school teacher and lives in the relatively prosperous region of Sughd, with better access to maternal health services than is found in other regions. However, medical costs are excessive for most people in the country,…
26 October 2021
Are COVID-19 vaccines safe for teenagers and children?
Some countries are already offering COVID-19 vaccines to teenagers and may expand this to children in the near future. Here’s what we know about vaccine safety and efficacy in these groups.
25 October 2021
COVID: how worried should we be about the new AY.4.2 lineage of the coronavirus?
This new sub-variant of the delta has gained a foothold in the UK.
25 October 2021
What you need to know about COVID-19 vaccines and rare neurological complications
Reports of Guillain–Barré syndrome or other neurological complications following COVID-19 vaccination are understandably worrying, but the first study to robustly investigate such links has found that the risk is much greater after COVID-19…
22 October 2021
Routine vaccines, extraordinary impact: Pertussis
Before immunisation for pertussis, or whooping cough, became routine, it killed twice as many children as measles and polio combined. High vaccine coverage is essential to keep that threat at bay.
22 October 2021
Togo becomes one of the first African countries to introduce digital vaccine passports
Togo is blazing a digital trail on the continent, looking to online tools, including digital vaccine passports, to curtail COVID-19.
22 October 2021
Women Leaders in Polio Eradication: Dr. Folake Olayinka
Dr. Folake Olayinka speaks about overcoming gender-related barriers to immunization.
21 October 2021
As India celebrated its one-billionth COVID-19 vaccination, #VaccinesWork caught up with Anuradha Gupta, Gavi’s Deputy CEO and an Indian public health veteran.
21 October 2021
Combining COVID-19 and routine vaccination: Nigeria implements a “whole family” approach
The whole family approach is helping Lagos State tackle multiple disease outbreaks and helping families lead healthier lives.
21 October 2021
A million a day: Pakistan’s COVID-19 vaccine campaign hits its stride
After a halting start to its immunisation campaign, Pakistan has shifted into high gear, now administering a million doses a day. #VaccinesWork spoke to national health leaders and spent a morning at a rural vaccination centre to find out what…
19 October 2021
Is it a cold or COVID-19? An expert explains
Research in the UK shows COVID-19 symptoms can be similar to the common cold. So, how can you tell the difference? Here, genetic epidemiologist Professor Tim Spector explains the latest data and what you need to know.
19 October 2021
Bringing routine immunisation back into focus in Ghana
Community health nurses in Ghana are on a mission to reverse the decline in routine immunisation since the start of the COVID-19 pandemic.
19 October 2021
Routine vaccines, extraordinary impact: Diphtheria
Before immunisation for diphtheria became routine, it was a major killer of children and adults worldwide. High vaccine coverage is essential to keep that threat at bay.
18 October 2021
COVID and flu: how big could the dual threat be this winter?
Social distancing has shielded us from other respiratory viruses – but that's not necessarily a good thing.
18 October 2021
Five reasons why ‘my body, my choice’ doesn’t work for vaccines
With several countries making COVID-19 vaccinations mandatory for health workers, teachers and other frontline staff, anti-vaccination protesters have co-opted the feminist slogan “my body, my choice” from reproductive rights and bodily autonomy…
18 October 2021
Vaccines save Eswatini’s education system
The delivery of COVID-19 vaccines has brought hope for the country’s education system.
15 October 2021
Convincing nomadic populations to get the jab in Northern Kenya
For the Gosha community, vaccines are not only protecting them from COVID-19, but are also bringing development to their area.
15 October 2021
Ten climate actions that could boost human health
Ahead of the COP26 climate summit, the World Health Organisation flags ten priority actions necessary to protect human and planetary health.
15 October 2021
Pandemica, a world where the pandemic goes on forever
Welcome to Pandemica, a world where twice as many people die and life as we once knew it does not return for anyone.
14 October 2021
First flight facilitated by the Hope Consortium touches down in Belgium with large delivery of ultra-cold chain freezers for onward shipment to 21 African countries.
14 October 2021
In the face of mounting logistical hitches, ordinary Nigerians are rallying behind health workers to ensure the success of COVID-19 vaccine rollout across the country.
14 October 2021
Why we still need vaccines even if we get new COVID-19 treatments
The pharma company Merck has applied for emergency use authorisation for an experimental COVID-19 antiviral treatment but, even if approved, such therapies won’t replace vaccines.
13 October 2021
Identifying people who have recovered from COVID-19 could provide a way to accelerate protection of populations against the disease.
13 October 2021
Without women there are no healthcare systems
The sixth annual Heroines of Health Gala celebrated seven women fighting to improve the health of their communities. From mobilising nurses in Beirut after the blast in August last year to helping communities in Ethiopia affected by the civil…
12 October 2021
COVID: why are people testing positive on lateral flow tests then negative on PCR?
The reasons for these results have yet to be confirmed – but maths may explain the phenomenon.
12 October 2021
The sports and entertainment communities of Eswatini are banking on COVID-19 vaccines to turn their fortunes around.
12 October 2021
Review: Preventing The Next Pandemic: Vaccine Diplomacy in a Time of Anti-Science
Dr Peter J. Hotez’ timely and important book underlines the fact that we need vaccine diplomacy now more than ever to overcome threats to our health.
11 October 2021
Mobilising mothers around immunisation in Nigeria
Going door-to-door, local community leaders are mobilising mothers to have their children immunised.
11 October 2021
How COVID-19 is contributing to period poverty in Nigeria
Skyrocketing prices for sanitary products, supply shortages and lockdowns are combining to make it harder and harder for girls and women in Nigeria to manage their periods.
8 October 2021
Breakthrough malaria vaccine offers to reinvigorate the fight against the disease
The WHO and the manufacturers of the vaccine will be rallying countries, particularly those with high malaria burdens, to adopt the vaccine.
8 October 2021
Drought may affect routine immunisation in Africa, study finds
Climate change is set to transform global health. A new study has found that droughts – one product of extreme weather exacerbated by climate change – may already be impacting rates of vaccination.
7 October 2021
Kenya is aiming to eliminate malaria entirely by 2030, with the world’s first malaria vaccine forming an important tool in its arsenal. The country’s youth is playing an important role.
7 October 2021
First ever malaria vaccine recommended by WHO: Q&A with Deepali Patel
The WHO recommendation on the RTS,S vaccine could protect millions of children across Africa.
5 October 2021
Nobel Prize: how chili peppers helped researchers uncover how humans feel pain
These discoveries could help us treat a variety of conditions in the future – including chronic pain.
5 October 2021
How will vaccinating camels boost uptake of COVID-19 vaccines?
Authorities in Kenyan border regions have come up with an innovative way to encourage COVID-19 vaccinations among herder communities: combine it with animal vaccination.
5 October 2021
Further vaccine R&D is critical to end the devastating COVID-19 pandemic
It is science that we must once again turn to so that we can remain one step ahead of the virus. Increased investment in ongoing vaccine R&D efforts will enable COVAX to deliver on its promises and ensure that our vaccines remain safe and…
4 October 2021
Head of UNAIDS unpacks the knock-on effects of COVID-19. And what needs to be done
Greater urgency is needed in the response to the pandemic, to end AIDS and to end COVID-19.
4 October 2021
Smokers were never really protected from COVID, despite what early studies claimed
How the 'smoker's paradox' went up in a puff of smoke.
4 October 2021
Super clean: Hand sanitiser helps prevent COVID-19, but what else is it doing to our health?
Hand sanitiser has become a regular feature of our lives since the start of the COVID-19 pandemic, but how effective is it – and is it a good idea to be so clean?
1 October 2021
The COVID-19 vaccine-shy are changing their minds
Vaccine hesitancy is “not a stable trait,” concludes a new American study, which found that a majority of initially hesitant respondents shifted their stance in favour of getting the jab.
1 October 2021
What we really know about waning COVID-19 immunity
Vaccines are still extremely effective at preventing severe disease. Waning antibody levels doesn’t always translate to lessening immunity.
1 October 2021
How COVID-19-related stress could be affecting your menstrual cycle
A new study suggests that more than half of women may have experienced irregularities in their periods after the COVID-19 pandemic began.
30 September 2021
Routine immunisation worldwide holds firm despite the pandemic
Despite the havoc wrought by the COVID-19 pandemic on health systems worldwide, governments’ work to bring immunisation programmes back on track is paying off.
30 September 2021
COVID-19 vaccines help routine immunisation become routine again in Nigeria
Routine immunisation took a hit in Nigeria thanks to the pandemic. Thanks to the arrival of COVID-19 vaccines, particularly for health workers, mothers are returning to immunisation clinics.
30 September 2021
Vaccinating domestic dogs reduces rabies in the wild. Why this matters
Domestic dogs have been shown to be the only species necessary to maintain rabies across most of Africa. This means that dog vaccination should control the disease in all species.
29 September 2021
More deliveries equals more demand for vaccines in South Sudan
With COVAX stepping up deliveries of COVID-19 vaccines in South Sudan, there is a steady increase in demand for the jab.
29 September 2021
Seven COVID-19 symptoms you shouldn’t ignore
Researchers have identified seven symptoms that are highly predictive of a positive COVID-19 test.
28 September 2021
Youth groups playing their part to boost COVID-19 vaccinations in DRC
Youth organisations in the DRC are doing their bit to change perspectives towards vaccinations.
28 September 2021
COVAX vaccines lead drive to reopen Uganda’s schools
The Ugandan government is on a drive to vaccinate teachers to ensure the reopening of schools across the country.
28 September 2021
What the world can learn from Bhutan’s rapid COVID vaccine rollout
Careful planning enabled this small, mountainous Himalayan country to vaccinate 90% of its adult population in three weeks.
27 September 2021
There is no vaccine equity without gender equality
On Thursday 23 September, on the sidelines of the UN General Assembly, global health leaders gathered to discuss gender equality in healthcare worldwide. Here’s what happened.
27 September 2021
Kids and COVID-19: what we know so far
Although children are less susceptible to COVID-19 than adults, there are still risks associated with infection.
27 September 2021
Whipping the Covid-19 vaccine market into shape
The COVAX vaccine procurement facility has run a remarkable race, but needs stable funding for long-term success.
24 September 2021
The pandemic has hurt women's health. This is why that's bad for everyone
The pandemic undermined women and girls’ fundamental rights and we must learn lessons about its impacts to build back better and ensure these groups aren't left behind. Empowering women and girls has proven to increase the health and well-being…
24 September 2021
COVID-19 is changing Kenyan nomads’ attitudes towards immunisation
COVID-19 is hitting nomads in Kenya’s Rift Valley hard. They are turning away from traditional medicine and customs as a result.
24 September 2021
Five reasons why it’s a terrible idea to hold a COVID-19 party (even if you’ve been vaccinated)
Although people who have recovered from COVID-19 may be less likely to catch it again, there are many reasons to avoid becoming infected in the first place.
23 September 2021
Your immune system is as unique as your fingerprint – new study
New discovery could help scientists develop more targeted drugs and vaccines.
23 September 2021
Study finds no increased risk of COVID-19 vaccination in pregnancy
Israeli data adds to mounting evidence that taking a COVID-19 vaccine during pregnancy is safe.
23 September 2021
Community health workers are critical in delivering COVID-19 vaccines
Delivering COVID-19 vaccines in low- and middle-income countries is only the first step in being able to vaccinate the world and bring this pandemic to an end. It’s essential to get vaccines from tarmacs into the arms of people living in last…
22 September 2021
Cholera and the inequitable origins of public health diplomacy
The arrival of cholera on European shores in the 19th Century helped kick off the long path towards modern global health institutions and diplomacy. However, these beginnings were anything but fair.
22 September 2021
Lower-income countries are letting far fewer COVID-19 vaccine doses expire than wealthier nations
Just 0.2% of COVID-19 vaccine doses delivered to lower-income countries through COVAX expired before they could be administered, estimated to be a significantly lower amount than wealthier countries.
21 September 2021
Togo leads the way in COVID-19 vaccine roll-out
With support from Gavi, WHO and UNICEF, Togo is introducing various mechanisms to turn the tide of COVID-19.
21 September 2021
Three things this week’s Global COVID-19 Summit is aiming to achieve
The White House is calling a virtual COVID-19 Summit on Wednesday, 22 September. Its targets for global vaccination are ambitious and essential as we work together to defeat COVID-19.
21 September 2021
The historic push to provide ultra-cold chain freezers around the world
Thomas Sorenson, Senior Manager in the Cold Chain Unit, UNICEF Supply Division, explains the work behind the scenes to roll-out the largest ultra-cold chain deployment in history.
20 September 2021
This is the WHO’s massive new list of ways to create a healthier, safer environment
Four UN agencies have compiled a first-of-its-kind Compendium of guidance on health and environment to help policymakers save millions of lives. The Compendium pulls together 500 actions and recommendations on everything from clean water and…
20 September 2021
COVID-19 vaccine roll-out gathers pace in Kisumu, Kenya
In Kisumu, which is still recovering from the after-effects of flooding, authorities are working to bring vaccines to the beleaguered residents.
20 September 2021
Reaching zero-dose children in Malawi’s cities
In Malawi urban areas have more unimmunised zero-dose children than rural regions. The government is working hard to close the immunisation gap.
17 September 2021
Gavi at UNGA: Action for equity
The 76th UN General Assembly (UNGA 76) will take place from 14-30 September 2021. Could we see a breakthrough in the fight for universal vaccine access?
17 September 2021
Even a quarter dose of Moderna vaccine triggers strong immune response
Although it’s not clear how this compares to the full dose licensed worldwide for emergency use, a quarter of a dose produces an equivalent immune response to immunity from infection.
17 September 2021
Vaccine justice: Nepal gives refugees priority in the vaccine queue
Nepal has distributed more than 10 million doses of COVID-19 vaccine according to a considered allocation schedule based on humane, inclusive, epidemiological good sense. The country’s future safety depends on the willingness of the rest of the…
16 September 2021
Now we know: typhoid conjugate vaccines are highly effective in African children
A study in Malawi found that TCVs are 84% efficacious among children 6 months to 15 years of age – the first such evidence among African children.
16 September 2021
We need to stop talking about COVID-19 waves
While vaccines have helped save millions of lives in this pandemic, the ever-evolving virus has spread so far that it may be here to stay.
16 September 2021
“We are not resting on our laurels”: COVID-19 survivors encourage vaccination in Nigeria
In Lagos, Nigeria's most populous state, COVID-19 survivors are encouraging more Nigerians to be vaccinated.
15 September 2021
Cameroon is dealing with two conflicts amid the pandemic
The war against Boko Haram in Cameroon's northern region and the struggle against armed secessionists in the west have taken a significant toll on vaccine roll-out.
15 September 2021
Why India’s latest Nipah case means pandemic preparedness is more vital than ever
With COVID-19 still ongoing, viruses like Nipah are nipping at its heels as the potential next pandemic threat.
14 September 2021
How COVID-19 is undermining maternal health and reproductive rights
As the African continent battles a third wave of coronavirus infections, access to reproductive health and rights is an ongoing challenge.
14 September 2021
Q&A: Helping teenage mothers access immunisation in Rwanda
The COVID-19 pandemic has reportedly increased the number of teenage mothers across Africa. Inadequate childcare support and stigma can prevent teenage mothers accessing routine immunisation and nutritional support for their infants. Girl Effect…
14 September 2021
No scientific basis for COVID-19 vaccine boosters in general populations
Even though many wealthy countries are planning to roll out booster doses, a Lancet review has concluded that the standard COVID-19 vaccination regimen is highly effective, even against the Delta variant.
13 September 2021
Kenya accelerates its COVID-19 vaccination programme
Kenya has ramped up its COVID-19 vaccination programme, expanding the list of who can get vaccinated.
13 September 2021
COVAX: the forecast for vaccine supply
While the supply is lower than predictions earlier this year, wealthy countries and manufacturers hold the power to improve supply.
13 September 2021
You don’t need to worry about COVID vaccines being ‘unnatural’ or ‘synthetic’
mRNA vaccines are the first synthetic vaccines, meaning they are made outside of a living cell. But so are lots of things we consume every day, such as vitamin C pills and other dietary supplements.
10 September 2021
Review: Survivors – Hope and Resilience in the Time of Ebola
The Sierra Leonean documentary is a complex portrait of courageous solidarity amid contagion.
10 September 2021
Pop culture icons and political satire in Bristol
The British artist John D’oh uses humour and wit to drive home messages about vaccines and other measures such as hand-washing and social distancing to stop the spread of COVID-19.
10 September 2021
We’re getting closer to a vaccine against Chikungunya
Launch of vaccine trial marks “significant milestone” towards beating this debilitating disease.
8 September 2021
Study of 6.2 million Americans shows no significant side effects from COVID-19 RNA vaccines
A study looking at health issues such as stroke or seizures after COVID-19 vaccination showed that vaccines weren’t linked to any significant number of side effects.
7 September 2021
COVID-19 vaccination halves the risk of Long COVID
Data from the UK suggests double vaccination lowers the risk of ongoing COVID-19 symptoms, as well as reducing hospitalisations and the severity of the initial illness.
7 September 2021
How improved yellow fever diagnostics are transforming management of the disease
Gavi has supported a major expansion in yellow fever diagnostic capacity in Africa over the past three years. The results show just how much improving diagnostics can have a cost-effective yet significant impact on immunisation programmes.
6 September 2021
Anand Kumar: From polio to para-sports world champ
More often than not, the road to a meaningful triumph is a bumpy one.
6 September 2021
COVID-19 vaccines are safe. Here’s why.
While most people jumped at the chance to get their COVID-19 vaccine, some have been more hesitant over concerns about safety. Here we explain all the checks and balances in place to make sure the vaccines are safe.
6 September 2021
The G20 Must Recommit to COVAX
Additional G20 support can make the COVID-19 Vaccine Global Access facility a success. Failure to achieve equitable access would mean more lives lost, broken health-care systems, even deadlier and more transmissible variants, and a pandemic with…
3 September 2021
Protecting a different kind of frontline worker in Liberia
Getting market women and pen-pen drivers vaccinated is critical to tackling COVID-19 in Liberia.
3 September 2021
Why helping countries deliver COVID-19 vaccines is just as vital as boosting supply
Getting COVID-19 vaccines out to countries isn’t just about ensuring supply – a major stumbling block can be their ‘absorptive capacity,’ or the ability to deliver the volume of vaccine coming their way. Here, we talk to Alex de Jonquieres,…
2 September 2021
COVID-19 boosted excess sale of antibiotics in India
COVID-19 boosted sales of antibiotic formulations used in adults and adolescents in India. Antibiotics should not be prescribed to treat viral diseases. Misuse of antibiotics can result in drug-resistant infections.
2 September 2021
Hantavirus study shows restoring forests can reduce zoonotic disease risk
Brazilian scientists have found that transmission of hantavirus, a deadly infection, could be reduced by 45% if Brazil restores its Atlantic Forest to levels mandated by its Native Vegetation Protection Law. Hantavirus, spresd by contact with…
2 September 2021
The vaccine taxi: Going mobile in Zimbabwe
Distance and fear of the pandemic has put many parents off from taking their children to health clinics in Zimbabwe. So one converted taxi is taking the clinic to them.
1 September 2021
The first human case of Marburg virus in West Africa is no surprise: here’s why
The Marburg virus will be present wherever the Egyptian Rousette bat occurs.
1 September 2021
What does the new C.1.2 coronavirus variant mean for COVID-19 vaccines?
A rapidly mutating coronavirus variant called C.1.2 is generating headlines around the world. Here’s what we know about it so far.
31 August 2021
Humanitarians Push to Vaccinate in Conflict Zones
Pandemic ceasefires offer an opportunity to expand vaccination efforts, experts say. But negotiation is tricky.
31 August 2021
People who have already had COVID-19 could be less likely to catch Delta than the vaccinated
A new study from Israel suggests the risk of a breakthrough infection among vaccinated people was higher than among people who’d previously had COVID-19 but had not been vaccinated. However the greatest benefit came to those who'd previously…
31 August 2021
COVID variants: we spoke to the experts designing a single vaccine to defeat them all
A universal vaccine has been described as the ‘holy grail’ – but how close are we to getting one?
30 August 2021
Do kids get long COVID? And how often? A paediatrician looks at the data
Children can get long COVID, but it seems to be less common than in adults. And they tend to recover quicker.
30 August 2021
More than a quarter of a million infants estimated to have died due to pandemic poverty
More than a quarter of a million infants in low- and middle-income countries are predicted to have died in 2020 due to the economic impact of COVID-19.
27 August 2021
With evidence showing the COVID virus is airborne, it's no coincidence many outbreaks in schools have occurred in winter – when windows are closed.
27 August 2021
Word of Mouth: Town criers boost COVID-19 vaccinations in Congo-Brazzaville
In Pointe-Noire city, the Republic of the Congo's economic capital, a group of volunteers working as town criers are winning the shouting match against the COVID-19 'infodemic.'
27 August 2021
With COVID-19 stretching the healthcare system in many parts of Nigeria, health workers and community leaders have to go the extra mile to ensure vaccines reach victims of the country’s latest cholera outbreak.
26 August 2021
Over a million children get protected against polio in Malawi
Malawi’s Ministry of Health recently conducted a nationwide polio vaccine catch up campaign targeting 1.8 million children who had previously missed out on the vaccine.
26 August 2021
Why kids in low-income countries could face a higher risk of dying of COVID-19
Children are increasingly falling sick worldwide, but existing poor health and inadequate access to health care means the most vulnerable kids are most at risk.
26 August 2021
A new study suggests the RTS,S malaria vaccine alone is as effective as preventive antimalarials; together they could save thousands of lives.
25 August 2021
In Brazil’s Acre, smoke from fires threatens health, could worsen COVID-19
Wildfire smoke has been linked to higher COVID-19 mortality rates, threatening to compound what is already one of the worst burdens of coronavirus infections and deaths in the world. At particular risk are Indigenous populations, who suffer…
25 August 2021
“We don’t want to end back at square one”: Keeping child immunisation alive in Kenya
Kenya’s community workers fight to continue vaccinating children during the pandemic to avoid the reversal of historic gains.
24 August 2021
After India’s brutal coronavirus wave, two-thirds of population has been exposed to SARS-CoV2
A public health scholar based in New Delhi explains how India has emerged from the massive spike in COVID-19 cases, even as the country braces for a new wave.
24 August 2021
Are COVID-19 vaccine mandates human rights violations?
Experts point to a more fundamental right to be protected from the disease, particularly as it continues to spread primarily among the unvaccinated.
23 August 2021
From volcano to outbreak: curbing the spread of cholera in the DRC
Aid agencies in Goma are joining efforts to contain cholera in the Democratic Republic of the Congo (DRC) after the eruption of the Nyiragongo.
20 August 2021
Why I no longer think we can eliminate COVID – public health expert
As New Zealand enters another lockdown after detecting a single COVID case, it's time to consider whether stringent zero COVID strategies are feasible in the long term.
20 August 2021
In the absence of good vaccines, doctors treating epidemic diseases must rely on cumbersome PPE as their one safety net. At least modern hazmat suits, unlike the 17th century plague doctor's all-leather outfit, actually work.
20 August 2021
How to eliminate cervical cancer - an expert explains
COVID-19 has caused a decline in the delivery of human papillomavirus (HPV) vaccines that protect girls from cervical cancer. Anuradha Gupta, the Deputy CEO of Gavi, explains what we must do to create more access to these vaccines.
19 August 2021
Zimbabwe’s waste pickers waiting impatiently for COVID-19 vaccines
For the waster pickers of Bulawayo, COVID-19 has posed risks to both their health and their incomes. Hope for a vaccine is reaching fever pitch.
19 August 2021
How artificial intelligence could help the fight against COVID-19
Using big data and deep learning, machines and systems are offering new ways of responding to a pandemic.
18 August 2021
COVID-19 boosters: Would a third jab really stop the pandemic?
Rich countries are now considering giving booster doses to vulnerable individuals, having fully-vaccinated most adults. Is this wise?
18 August 2021
Is modern life encouraging the evolution of deadlier viruses?
The way we live can shape the evolution of pathogens, for better or worse.
18 August 2021
Vaccines can win the race against COVID-19 variants. Here's how
COVID-19 variants threaten to undermine global vaccine programmes unless we accelerate the pace of delivery and rise to the challenge of global deployment.
17 August 2021
Should we tell stories of vaccine sceptics who have died of COVID?
The news is full of stories of people who refused the jab who died of COVID.
17 August 2021
Clinics get routine immunisation back on track in Zimbabwe
The onset of the COVID-19 pandemic hit routine immunisation hard in Zimbabwe, but thanks to the hard work of local health workers children are now getting the protection they need.
17 August 2021
COVID-19: why we can’t use antibody tests to show that vaccines are working
Many COVID-19 antibody tests are not designed to specifically detect antibodies that develop as a result of vaccination, and thus cannot show whether antibodies are of the right quantity or quality for protection against infection or illness.
16 August 2021
Vaccines bring hope for children in Nigeria’s largest coastal slum
Access to routine immunisation and primary health care is changing the lives of children in Makoko, Nigeria’s largest coastal slum.
16 August 2021
Are chatbots better than humans at fighting vaccine hesitancy?
Could artificial intelligence succeed where people have failed in helping people overcome their fears about vaccines?
13 August 2021
Investing in Global Vaccine Equity Acknowledges Our Shared Fate
Vaccines are among modern medicine’s greatest innovations, allowing billions of people to lead healthy lives. But stopping outbreaks of vaccine-preventable disease – and not only COVID-19 – depends on achieving critical mass with immunization…
13 August 2021
Plagues and classical history – what the humanities will tell us about COVID in years to come
We all need to know about the science of COVID as we battle through pandemic, but the ultimate story will lie in how it changed our society.
13 August 2021
TCV is 85% efficacious and urgently needed for Bangladeshi children
New study finds TCV prevents 85% of cases among vaccinated children in Bangladesh, which has one of the highest typhoid burdens in the world.
12 August 2021
Nigeria’s new initiative to boost routine immunisation
To improve routine immunisation, Nigeria is implementing the Accelerated Action for Impact (AAI) initiative.
12 August 2021
Why are fully-vaccinated people still catching COVID-19?
Breakthrough infections are to be expected, but it doesn’t mean the COVID-19 vaccines aren’t working.
11 August 2021
How will COVID vaccines work on compromised immune systems? Here’s what we know
Being immunocompromised appears to affect the vaccine response, but this seems to vary depending on the causes of the person's low immunity.
11 August 2021
How bad will climate change be for our health?
The latest IPCC report emphasises the inevitability of some degree of climate change. The human health impact of this should not be ignored.
10 August 2021
John Snow and the Pump Handle of Public Health
The narrative of the Broad Street pump is the story of a vital epidemiological discovery; it’s also a story about discovery: it has the tidy, conclusive quality of a fable about science. But in the years after its discovery, John Snow’s theory of…
10 August 2021
COVID-19 versus routine immunisation in the Democratic Republic of Congo
Health workers, community leaders and the Ministry of Health are hard at work trying to contain the damage COVID-19 is causing routine immunisation in the DRC.
9 August 2021
RSV: what is it, and why are child cases surging in the wake of COVID?
COVID restrictions have prevented the spread of other respiratory viruses too. As these are lifted, the UK government has warned parents of a delayed surge in infections.
9 August 2021
That Old Time Anti-Vaxx Feeling
The best single predictor of vaccine uptake per US state is not political affiliation, but the share of the population that believes the human race has always existed. Such findings do not bode well for the global effort to boost vaccination…
9 August 2021
If we’re not careful, booster vaccines could end up giving the coronavirus a boost
The sooner we start using booster jabs, the more likely it is that we will need them.
6 August 2021
COVID: why you still need to wash your hands
Respiratory viruses, such as influenza and SARS-CoV-2, while spread primarily by respiratory droplets can also be spread by contaminated hands touching the mucous membranes of the nose, mouth and eyes.
6 August 2021
In 2014, Nigeria escaped an Ebola pandemic in the span of 93 days because of the bravery and quick response of health care workers in Lagos. As the world fights through the COVID-19 pandemic, the film 93 Days – though grim – is a hopeful reminder…
5 August 2021
Reaching out to communities in rural Zambia
In rural Zambia, clinics and health centres rely on a limited number of medical personnel to run immunisation programmes, which makes the support of community leaders vital.
4 August 2021
Review: The Cutter Incident by Paul Offit
Offit’s sobering inquiry into “one of the worst biological disasters in American history” is a work of unflinching investigative journalism which lands, finally, not as a whodunit, but as a tribute to modern systems of meticulous vaccine…
4 August 2021
How do experts ensure vaccine safety?
From clinical trials to population surveillance, these are the multilevel mechanisms that ensure vaccine safety – including the safety of COVID-19 vaccines.
3 August 2021
Intellectual Property and COVID-19 vaccines
During a pandemic supply bottlenecks of essential medical products are almost inevitable, but with COVID-19 this has been further exacerbated by governments hoarding doses and imposing export bans.
3 August 2021
Refugees included in Uganda’s COVID-19 vaccine drive
Uganda is setting an example by including its estimated 1.4 million refugees in its COVID-19 vaccine programme, however there are still barriers to overcome.
30 July 2021
A Deadly Alliance – War and the Pandemic Influenza of 1918
As World War I reached its climax, a terrible influenza pandemic broke out. By summer 1919, it had claimed many more lives than the conflict – but the conflict, researchers say, helped create the conditions for the devastating spread of the so-…
30 July 2021
Kenya’s digital vaccine warriors
The Savannah Innovation Hub teaches young women in Garissa County to counteract COVID-19 vaccine misinformation from groups like Al-Shabaab.
29 July 2021
“My heart is always stuck in my homeland”: A Rohingya returnee’s story
Abdullah and his family escaped genocidal violence in Myanmar in 2017, survived a diphtheria epidemic in Bangladesh’s Cox’s Bazar and weathered the first year of the COVID-19 pandemic in a Rohingya camp. Then, in December 2020, he returned to the…
29 July 2021
“Saving the future of our children”: The women fighting polio in Pakistan
Pakistan is one of two countries where wild poliovirus remains endemic making it essential that the entire country supports the successful implementation of every polio campaign. Women play a critical role, often working at polio’s frontline.
28 July 2021
Fighting liver cancer with vaccines in The Gambia
Vaccines against cancer may seem like a futuristic notion, but children around the world are already getting protection against two of the biggest causes of cervical and liver cancer: HPV and hepatitis B.
27 July 2021
COVID masks: how and when to ask someone to wear one – without getting into a fight
Just because face coverings aren't mandatory doesn't mean they're not protective – so here's how to ask someone to wear one.
27 July 2021
Review: COVID, Quickly – A Scientific American podcast series
This series cuts through the noise to help you catch up with the latest COVID-19 developments in an entertaining and digestible way.
26 July 2021
“I will definitely take the vaccine”: High demand for COVID-19 vaccines in Uganda
While there was some initial reluctance to get vaccinated against COVID-19 in Eastern Uganda, attitudes are changing fast.
23 July 2021
TB prevention has relied on the same vaccine for 100 years. It’s time for innovation
BCG remains the only widely available vaccine for TB. Yet the development of a COVID-19 vaccine over the last year shows that there is capacity to rapidly create new vaccines.
23 July 2021
How effective are COVID-19 vaccines in the real-world?
Real-world data is starting shed light on the performance of COVID-19 vaccines in less than perfect conditions.
23 July 2021
Q&A: Vaccine – The Human Story
Dr Annie Kelly, writer and host of a new podcast which tells the story of the smallpox vaccine, talks to #VaccinesWork.
22 July 2021
Review: The Panic Virus by Seth Mnookin
Mnookin’s 2011 investigation of the spread of anti-vax feeling is a pandemic-era must-read.
22 July 2021
New vaccination figures underscore urgency to reach the most vulnerable
New data shows the impact COVID-19 is having on routine immunisation programmes worldwide, particularly in lower-income countries. We need action, now, to get routine immunisation programmes back on track and ensure that everyone, everywhere is…
21 July 2021
From town criers to local monarchs: encouraging COVID-19 vaccination in Southern Nigeria
Volunteers, including King Dakolo of the Epetiama kingdom, are sensitising and convincing people to accept the COVID-19 vaccine in Bayelsa State, Southern Nigeria.
21 July 2021
Rather than translating their own COVID-19 vaccination successes into a renewed global push to end the pandemic, rich countries are becoming complacent while the rest of the world grows increasingly desperate. But the emergence of dangerous new…
21 July 2021
Nurses on the COVID-19 frontlines in Sierra Leone
#VaccinesWork spoke to nurse Fatmata Kamara* about how the COVID-19 vaccine roll-out in Sierra Leone is progressing.
20 July 2021
How investigation into long COVID will help us create treatments.
20 July 2021
The COVAX No Fault Compensation Programme: Explained
Indemnity and liability was one of the thorniest problems COVAX had to solve to successfully roll out COVID-19 vaccines in lower-income countries. The solution is a world first, which could offer a model for future pandemics.
19 July 2021
Willing and waiting: High levels of COVID-19 vaccine acceptance identified in Global South
The widespread acceptance of COVID-19 vaccines in low- to middle-income countries should boost global coronavirus immunity, if distribution issues can be resolved.
19 July 2021
Keeping routine immunisation going during Uganda’s second lockdown
Despite a second lockdown, outreach initiatives ensure continuation of Uganda’s routine child immunisation.
19 July 2021
Why Africa needs to manufacture its own vaccines
Dr John Nkengasong is a Cameroonian virologist and Director of the Africa Centres for Disease Control and Prevention (Africa CDC), which is working to strengthen the ability of Africa’s public health institutions to detect and respond to disease…
16 July 2021
COVID: should you ditch your mask once restrictions are lifted? A philosopher’s view
A philosopher of public health ponders whether taking your mask off on July 19 is like punching someone in the face or like riding a bike.
16 July 2021
How Do We Track Vaccinations for People Who Don’t Formally Exist?
Yoshinobu Nagamine, Senior Donor Manager at Gavi, the Vaccine Alliance, describes the role contactless biometrics can play in accelerating vaccine delivery for those lacking formal identification.
15 July 2021
COVID-19: how a sense of community can increase vaccine uptake
If people feel a sense of duty to their local community, they're more likely to protect themselves and others by taking the COVID-19 vaccine.
15 July 2021
What can Nigeria do to boost local production of vaccines?
COVID-19 has made local, home-grown production of vaccines a national priority in countries around the world. #VaccinesWork spoke to Professor Martins Emeje at Nigeria’s National Institute for Pharmaceutical Research and Development (NIPRD) to…
14 July 2021
We should treat COVID like norovirus – not the flu
Comparisons with flu are unhelpful – these diseases need to be treated differently.
14 July 2021
Pen and paper in a digital age: tracking childhood immunisation in Kenya
It may not be high tech, but it works. Kenyan community health volunteers use tracking books to ensure that children receive routine vaccinations.
14 July 2021
Will COVID-19 evolve to be more or less deadly?
Some viruses gradually become less virulent over time, but there's no guarantee that SARS-CoV-2 will follow that pattern.
13 July 2021
COVID: lambda variant is now in 29 countries, but what evidence do we have that it’s more dangerous?
The lambda variant ripped through Peru and is now spreading globally. But there is little evidence that it is more dangerous than the original variant.
13 July 2021
Could a universal coronavirus vaccine soon be a reality?
COVID-19 is unlikely to be the last coronavirus we ever see. Scientists are already trying to make a one-size-fits-all vaccine to stop a future coronavirus epidemic in its tracks.
13 July 2021
Could the seasonal flu vaccine help protect against COVID-19?
A large study suggests the influenza vaccine may reduce the risk of some of the worst consequences of COVID-19.
12 July 2021
Community Health Workers stop the spread of COVID-19 and polio in Nairobi’s slums
Community health volunteers collaborated with local structures in the slums to help inhabitants survive lockdown and stop the spread of disease.
12 July 2021
COVID-19 vaccine boosters: is a third dose really needed?
If immunity is waning or ineffectual against new variants, then boosters could be needed – but there needs to be evidence that they're necessary.
9 July 2021
Why Africa’s push to make vaccines should look further than COVID-19
Vaccine manufacturing doesn't come cheap. It depends heavily on support from developed countries. It also takes much more than relaxing intellectual property rights and a desire for vaccine equity.
9 July 2021
Are new variants making the COVID-19 virus as deadly as SARS?
Although related to the virus that caused the SARS pandemic in 2003, the COVID-19 virus has never seemed as deadly – until now.
8 July 2021
Handwashing ‘impossible’ for one in three amid COVID-19
One in three unable to properly wash hands at home during COVID-19 – WHO-UNICEF. Progress on water, sanitation and hygiene ‘must quadruple’ to meet 2030 target. Investment and prioritisation needed ‘at the highest levels’.
8 July 2021
Is COVID-19 effectively already endemic?
Will the pandemic go out with a fizzle or a bang? And what does “living with the virus” actually mean, and when will we get there?
8 July 2021
Opinion: Reach 'zero-dose' children to build back better
We must seize this opportunity to shape our COVID-19 response as a chance to achieve better equity and social justice. What better way to do that than to focus on zero-dose children?
7 July 2021
COVID variants: could dangerous new ones evolve in pets and farm animals?
Early results from several studies have found that pets can pick up COVID-19 from their owner – but they are unlikely to be dangerous as a result.
7 July 2021
Five ways to mitigate India’s third COVID-19 wave
India’s second wave of COVID-19 has devastated the country through a perfect storm of new variants, low vaccination uptake and a shortage of medical equipment and supplies. Here’s what we need to understand about the ongoing second wave to…
6 July 2021
India’s “Covaxin” vaccine shows high efficacy against COVID-19 infections in phase 3 trial
A vaccine that had previously been authorised by the Indian government ahead of phase 3 trials now show promising results. This could add to the global armoury of vaccines against COVID-19.
6 July 2021
Africa ‘tech hub’ aims to fill COVID-19 vaccine gap
New mRNA tech transfer hub to be established in South Africa. Facility will provide training and licences for vaccine development. Less than one per cent in Africa have been vaccinated against COVID-19.
5 July 2021
Unlocking Girls’ Potential Through Technology
The pandemic has exacerbated pre-existing inequalities, not least those disadvantaging women and girls in low- and middle-income countries. Fortunately, with today’s digital technologies, those providing health information and services for girls…
5 July 2021
Kenyans use their polio fighting network to tackle COVID-19
A rich network of community volunteers in Nairobi are putting skills they developed during anti-polio activities to work tackling COVID-19, and mobilising slum dwellers to get the COVID-19 vaccine.
5 July 2021
False negative: How long does it take for coronavirus to become detectable by PCR?
It takes time for coronavirus to become established in the body, so a negative test doesn’t necessarily mean you won’t test positive later on.
2 July 2021
The power sources used to keep vaccines cold used to be polluting and unreliable. We spoke to Alex de Jonquieres, Gavi’s Director of Health Systems and Immunisation Strengthening about how Gavi, the Vaccine Alliance, became investors in solar…
2 July 2021
How Can I Spot A Fake COVID-19 Vaccine?
Fake COVID-19 vaccines erode public trust in much-needed jabs and encourage vaccine hesitancy.
1 July 2021
Before 1955, when a vaccine first made polio a preventable illness, the paralysing disease had to be treated. For many, the best option was the iron lung, a device that came to symbolise an era of anxiety in mid-20th century America.
1 July 2021
Why sharing bioimaging tech is crucial to global health
New bioimaging technologies are pushing the boundaries of medicine. But poorer nations risk losing out on these advances. Investment in facilities and training globally is crucial to bridge the divide.
1 July 2021
Are men and obese people really at greater risk of dying from COVID-19?
A reanalysis of 58 existing studies suggests that with COVID-19 being male or seriously overweight isn’t as risky as originally thought.
30 June 2021
How vaccines "demolished the wall" COVID-19 built between Nigerians and their loved ones
Separated for weeks and months because of the COVID-19 pandemic, the arrival of vaccines is allowing people to physically reconnect with friends and family.
30 June 2021
How to Prevent the Next Pandemic
We need to make the development and distribution of vaccines a truly global endeavor.
29 June 2021
There’s now a Delta Plus variant of COVID-19 – what does this mean?
The Delta variant that has caused devastation in countries like India and the UK has now mutated to produce another variant called Delta Plus. Should we be worried?
29 June 2021
Guinea declares Ebola epidemic over
Guinea declares end of Ebola outbreak after 42 days without new cases. Outbreak resulted in 23 likely cases, 12 deaths since February. Success attributed to community buy-in, capacity building and vaccination.
29 June 2021
By identifying people with high levels of neutralising antibodies after a first vaccine dose, rapid tests could potentially identify those who don’t need a booster dose.
28 June 2021
What you need to know about COVID-19 vaccines and myocarditis in teens
This rare side-effect from the two RNA vaccines being rolled out might be concerning but the benefits of vaccination far outweigh the risks.
28 June 2021
COVID-19 vaccines: why it’s important you get your second dose
Two doses have always been more protective than one, but the Delta variant has made the benefit of the second dose much greater.
28 June 2021
The Immunization Agenda 2030’s new scorecard visualizes a journey toward pandemic recovery and global immunization progress.
25 June 2021
I’m fully vaccinated but feel sick – should I get tested for COVID-19?
Vaccinated people can still get infected with the coronavirus. So if you have symptoms of COVID-19, getting tested can protect others and help health officials keep an eye on the virus.
25 June 2021
“My world became smaller”: How COVID-19 vaccines are fighting stigmatisation in Nigeria
Forced to suffer in silence after contracting COVID-19, the arrival of vaccines is helping many Nigerians with a history of the virus overcome stigma and get their lives back on track.
25 June 2021
Despite the pandemic, Kenya rolls out measles-rubella vaccinations
Beginning today, Kenya’s Ministry of Health is beginning a major new measles-rubella vaccination campaign to defend against outbreaks.
24 June 2021
The COVID-19 pandemic has affected turn out for almost all Malawi’s health services, including routine immunisation. One local CSO is using Community Mother Care groups to trace those missing out on vaccines, helping to ensure children are…
24 June 2021
How the pandemic is fuelling antimicrobial resistance
For years, a growing number of infections that are resistant to antimicrobials has offered us a grim glimpse into a future with increasingly untreatable diseases. Now, COVID-19 has made antimicrobial resistance so much worse.
23 June 2021
New systems map can help overcome difficulties in vaccinating hard-to-reach communities
A major obstacle for COVID-19 vaccination programs to achieve higher and more equitable vaccine coverage throughout the world is vaccinating hard-to-reach communities.
23 June 2021
What does COVAX’s latest supply forecast tell us?
The forecast is encouraging given the supply disruptions COVAX and countries with bilateral deals are currently experiencing, and the general challenges manufacturers are experiencing as they ramp up supply at historic speed and scale.
23 June 2021
Could lifting COVID-19 restrictions trigger a surge in other common infections?
Masks, hand washing and physical distancing don’t only reduce the transmission of coronavirus. So, what will happen when we do away with these measures?
22 June 2021
We archived 84 million tweets to learn about the pandemic – each one is a tiny historical document
During the pandemic, researchers have treated Twitter as a sprawling and evolving historical document.
22 June 2021
What happens when COVID-19 collides with HIV infection?
Mounting evidence suggests people living with HIV may be at greater risk of dying from COVID-19. The good news is that COVID-19 vaccines appear to be safe and effective in people with HIV.
21 June 2021
Giving 110%: Eswatini’s early rollout of COVID-19 vaccines
Eswatini received its first batch of 32 000 Oxford-AstraZeneca vaccines in late March. 12 000 came through the COVAX facility and 20,000 through a donation from the Indian Government.
21 June 2021
How vaccines turbo-charge any existing immunity against COVID-19
A previous infection does give you some immunity against COVID-19, but a new study suggests that vaccination gives your body a massive boost – including against variants of concern.
21 June 2021
Q&A with Sterling and Seth: Spotlight on COVAX
What do the CEO of the Vaccine Alliance and the star of a hit US TV show have in common? They both want to raise awareness about COVID-19 vaccines and COVAX’s role in getting the world vaccinated.
18 June 2021
Mary Mallon was branded a public menace and incarcerated after typhoid outbreaks across New York City were linked to her presence in the kitchen. Was she unfairly demonised?
18 June 2021
Five Good Reasons to Go Give One
Wondering what you can do to help end the acute phase of the pandemic? Go Give One – is giving everyone everywhere a chance to play their part.
18 June 2021
Why we support COVAX: Mastercard
Mastercard, a long-standing partner of Gavi, recently committed US$ 28 million to the Gavi COVAX AMC, to ensure vaccines are accessible to those that needed them the most, no matter where they live. Vaccines Work spoke to Michael Froman to learn…
17 June 2021
Seven ways in which COVID-19 could change the way we fight infectious diseases
The pandemic turned our normal ways of working upside down, but there are several ways in which the new normal could bring improvements in the way we fight disease.
17 June 2021
Lifesaving but unaffordable: pros and cons of the newest COVID-19 treatment
Antibody therapy reduces COVID-19 fatalities by a fifth, but remains inaccessible to many countries.
17 June 2021
Needle phobia could be the cause of 10% of COVID vaccine hesitancy in the UK – new research
People who are afraid of needles are twice as likely to be vaccine hesitant, new research shows.
16 June 2021
Why we still need R&D into COVID-19 vaccines
There are now 17 COVID-19 vaccines approved for emergency use, but as the virus continues to evolve, here is why we can’t pull the plug on research into new vaccines and therapeutics.
16 June 2021
How COVID-19 will damage the lives of African children for decades to come
Although the coronavirus doesn’t cause disease and death in children as much as it does in adults, many children around the world are vulnerable to the collateral damage wreaked by the pandemic.
15 June 2021
Does a plant-based diet really help beat COVID-19?
A new paper suggests that plant- and fish-based diets lessen the chance of developing severe symptoms – but hold off from becoming vegetarian or pescatarian for now.
15 June 2021
Five things we know about the Delta variant (and two things we don't)
The Delta (B.1.617.2) variant of SARS CoV-2 was first detected in India and is rapidly spreading around the world. Here’s what we know about it so far.
14 June 2021
Why speaking without a mask is the easiest way to spread COVID-19
COVID-19 virus particles can be spread via coughing, sneezing, breathing or speech, but the latter is one of the most effective ways of spreading. Here is why talking without a mask indoors could be one of the easiest ways to spread the infection…
14 June 2021
Floods hampering the vaccine roll-out in Western Kenya
Amidst the challenges that COVID-19 has brought, flooding in Kenya has made it even harder for the people of Kisumu County.
14 June 2021
How well do first and second vaccine doses work against Covid-19?
Is it risky or wise to delay the second dose of Covid-19 vaccine? Critics warned against the UK government policy of leaving a longer gap between doses of the Pfizer-BioNTech and Oxford-AstraZeneca vaccines. Now we have more data, so what do we…
11 June 2021
Countries must share COVID-19 vaccine doses; the sooner the better
Some of the world’s wealthiest countries nations have already committed to share doses with lower-income countries through COVAX: as G7 leaders meet this week, other governments must follow suit and share their doses now, because we only have a…
11 June 2021
Do COVID-19 vaccines affect menstruation and fertility?
Ever since the pandemic started there have been news headlines speculating about the effect of the vaccines on our reproductive system, but what does the science tell us?
11 June 2021
From the great plague to the 1918 flu, history shows that disease outbreaks make inequality worse
Accounts of previous epidemics – by Samuel Pepys, Daniel Defoe and Katherine Porter – warn of mistakes that we risk repeating.
10 June 2021
Tackling typhoid in Zimbabwe: “We have to be sure for ourselves that the water is safe”
After a devastating typhoid outbreak swept through Bulawayo, Zimbabwe, a new, more effective vaccine is bringing hope.
10 June 2021
Six ways to know the COVID-19 pandemic is over
It’s been over a year now since the pandemic first started, and now that vaccines are rolling out in many countries, how long do we have to wait for things to go back to ‘normal’?
10 June 2021
To keep coronavirus at bay, we must create a ‘variant-proof’ world
We remain locked in a deadly race with the virus. We will only win when we have created a “variant-proof” world that can keep a lid on the havoc caused by its troublesome mutations.
9 June 2021
The ‘black fungus’ epidemic hitting COVID-19 patients in India
Amid the 28.4 million cases and over 300 thousand deaths from SARS-CoV-2, a second epidemic has hit India. ‘Black fungus’, clinically known as mucormycosis, is an infection currently affecting nearly 12,000 immunocompromised patients recovering…
9 June 2021
While we don't know exactly what causes it yet, there are a few theories put forward by a few researchers around the world.
9 June 2021
How likely is a positive COVID-19 lateral flow test to be wrong?
Rapid antigen tests for COVID-19 are less sensitive than PCR tests, but here we explain why you should never ignore a positive result.
8 June 2021
Is 150 years really the limit of human lifespan?
Researchers think they've calculated the limit of human lifespan – but there's more to it.
8 June 2021
“This country belongs to all of us”: Vaccinating internal migrants in Nigeria
For those who migrate within Ondo State, Nigeria, access to immunisation has been complicated by the shift in focus to COVID-19.
8 June 2021
Speeding up vaccine development: Can we go from lab to jab in just 100 days?
COVID-19 vaccines were made in record speed, taking around 300 days from the moment the threat was first identified. But the world’s top scientists are aiming to overtake this world record in the next pandemic, aiming to make a vaccine in 100…
7 June 2021
Can dogs be trained to sniff out COVID-19?
Various countries are training dogs to detect coronavirus, and the results of early clinical trials are looking promising.
7 June 2021
COVID-19's impacts on the brain and mind are varied and common – new research
Non-specific illnesses, such as headache and fatigue, are common, as are mental illnesses such as depression and anxiety.
7 June 2021
LGBTIQ people have been hit hard by COVID-19. Here’s how we can all help
Marginalized people suffer from being at the intersection of multiple challenges and barriers. Economic hardship has been a secondary epidemic in the LGBTIQ community. We need public health and support services that acknowledge difference.
4 June 2021
Five reasons why the real number of COVID-19 deaths could be triple the official number
The death toll from the pandemic has been devastatingly high, with the official figure standing at 3.5 million people, but the World Health Organization estimates the real number could be up to three times higher. Here’s why.
4 June 2021
Little-Known Illnesses Turning Up in Covid Long-Haulers
A significant number of post-covid patients suffer from syndromes that few doctors understand.
4 June 2021
Get the jab! COVID-19 vaccination in Goma
Community health workers, government and aid agencies join a chorus of voices encouraging vaccinations in the DRC.
3 June 2021
How well your immune system works can depend on the time of day
Our immune system is controlled by our "body clock" – an intricate 24-hour system which controls how cells function.
3 June 2021
Nigerians turn to social media for encouragement
Social media has been much-maligned as a source of misinformation when it comes to vaccines. But for millions of Nigerians it is having the opposite effect, encouraging them to get their jabs.
2 June 2021
Why COVID-19 variants got new Greek names
Calling variants by their country of origin has politicised the pandemic response, leading to countries being blamed and people originating from those countries stigmatised and targeted – sometimes violently. Now, the World Health Organization is…
2 June 2021
How the predicted hunger pandemic became a grim reality
Worldwide more than 3.5 million people have died of COVID-19 so far; now millions more are on the brink of starvation because of a connected hunger crisis.
2 June 2021
Can you test positive for COVID-19 test after getting the vaccine?
As more people get vaccinated, and testing requirements are becoming commonplace to allow freedom to travel and work, we look at the circumstances under which you could test positive for COVID-19 even after being vaccinated.
2 June 2021
World leaders and private sector commit to protecting the vulnerable with COVID-19 vaccines
In the COVAX Advance Market Commitment Summit, hosted by Japan, countries and industry came together to pledge support to the mission of making vaccines available equitably worldwide.
2 June 2021
World leaders unite to commit to global equitable access for COVID-19 vaccines
The Gavi COVAX AMC Summit “One World Protected” virtual event, hosted today by the Government of Japan and Gavi, the Vaccine Alliance, raised US$ 2.4 billion from nearly 40 donor governments, the private sector and foundations, exceeding the…
1 June 2021
COVID-19 in the house: How to reduce the risk of transmission
Further infections are not inevitable, if you take the following steps.
1 June 2021
Change to cold-storage conditions could make Pfizer COVID-19 vaccine more widely available
Several regulators have agreed the mRNA vaccine can be kept refrigerated for up to 30 days, making it easier to distribute in lower-resource settings.
1 June 2021
If you’ve had COVID-19 you could be more than 80% protected from reinfection
Whether or not you can become reinfected with COVID-19 hasn’t been clear so far, but a new study from Denmark indicates that immune response triggered by the first infection offers good protection.
31 May 2021
Self-COVID-19 tests: do you know your tonsils from your uvula?
Some COVID-19 tests require you to swab your own tonsils, but could you be mistaking them for something else?
31 May 2021
How the answer to long-lived immunity to COVID-19 could lie in our bone marrow
People who have had COVID-19 seem to have bone marrow cells that could produce antibodies for years to come, which could mean that immunity both from natural infection and vaccination is long lasting.
31 May 2021
Keeping vaccines cool with cold chain
With millions of COVID-19 vaccines now being delivered around the world, they are utilising a huge hidden infrastructure, built up over decades and spreading across the globe, with one ultimate goal: keeping the vaccines cool. How did these …
28 May 2021
What steps must be taken to secure oxygen - for COVID-19 patients and into the future
New waves of the COVID-19 pandemic in countries, such as Kenya and India, have exposed the poor management of oxygen supplies. Moina Spooner, from The Conversation Africa, asked Professor Trevor Duke, an expert on [oxygen provision] and editor of…
28 May 2021
Encouraging vaccination in Nairobi: “If we work on awareness and motivation, we are good to go”
Pamela Anyango is on a mission to boost vaccine coverage in Dandora, Kenya, home to a garbage dump that has been labelled the ‘cradle of the next pandemic’.
28 May 2021
Is it safe to mix and match COVID-19 vaccines?
Mixing COVID-19 is being proposed in some countries but is it safe to do so, and how do our immune systems react?
27 May 2021
Malawi takes on religious beliefs that discourage immunisation
Malawi’s Ministry of Health is using its structures to reach out to a small section of religious groups that are threatening the success of the country’s immunisation programme.
27 May 2021
Yellow Fever and the Panama Canal
At the turn of the 20th Century, US researchers in Cuba made the historic discovery that mosquitoes spread yellow fever. The finding was not only a medical breakthrough; it would also make possible one of the world’s greatest feats of engineering…
26 May 2021
Could a new coronavirus be spreading from dogs?
Scientists think they may have caught a canine coronavirus in the process of adapting to humans.
26 May 2021
The point of it: Why do vaccine delivery methods vary?
Some vaccines are injected into muscle; others are given orally, or under the skin. What difference does it make to our immune response?
26 May 2021
How to give a COVID-mitigated hug
No activity that brings you into someone else’s breathing space is safe, but the risks associated with hugging can be lowered by taking some simple precautions.
25 May 2021
Filling the vaccine gap in Kenya
A well-planned immunisation programme can go a long way to reducing the burden of disease on a country.
25 May 2021
“We survived something major together”: Rebuilding after COVID-19
COVID-19 put a huge strain on Seyram and his mother’s relationship, as well as on their individual lives. The delivery of Ghana’s first batch of vaccines from COVAX means they can begin to rebuild what was broken.
25 May 2021
Coronavirus: so many variants, but vaccines are still effective
Variants of interest and variants of concern seem to be popping up at an alarming rate. But how many of them do we really need to worry about?
21 May 2021
How Yellow Fever decimated the USA’s first capital
In 1793, with the United States of America less than 20 years old, a yellow fever epidemic decimates the capital city, Philadelphia, and shines a spotlight on stark racial and social inequalities.
21 May 2021
Can we stop wearing masks after being vaccinated?
In some countries, wearing masks against COVID-19 is not mandatory anymore, but can the rest of the world follow suit?
21 May 2021
Apostolic Churches warm up to COVID-19 vaccines in Zimbabwe
Attitudes towards vaccines are changing as Zimbabwe’s Apostolic Church members come to terms with COVID-19.
21 May 2021
Why Africa’s critically ill COVID-19 patients have the world’s highest death rates
Death rates on the continent are higher than Asia, Europe, North America or South America, in large part because of a lack of resources and underuse of resources that do exist.
20 May 2021
COVID-19: how rising inequalities unfolded and why we cannot afford to ignore it
It's been argued that pandemics are the great leveller, but with COVID the opposite is true – and we can't afford to ignore it.
20 May 2021
The community health workers getting people vaccinated in Uganda
As Community Health Workers, Harriet Nankwanzi and Yusuf Maganda have built personal relationships with people in their communities who have over the years relied on their services to access vital health information.
20 May 2021
Asia and Africa offer lessons in health systems resilience
In this pandemic, the income level of a country proved not to be a guarantee of an effective COVID-19 response; this analysis shows the key factors in a resilient health system to protect against future outbreaks.
19 May 2021
Do children need to be vaccinated against COVID-19?
Children have so far been able to evade the worst effects of COVID-19, but this could be changing as new variants and other factors seem to be putting more at risk.
19 May 2021
Poo and the pandemic: How sewage is helping us fight COVID-19
Many countries are beginning to use wastewater monitoring to track COVID-19 outbreaks, but such sewage surveillance has a long history.
19 May 2021
“If we don’t go out there, nobody would”: Vaccinating during an insurgency in Nigeria
Health workers go above and beyond the call of duty to ensure that the children of Borno State, Nigeria, are vaccinated.
18 May 2021
The impact of COVID-19 on Malawi’s routine immunisation programmes
The pandemic is having an adverse effect on Malawi’s continued drive to provide all children with routine vaccines.
18 May 2021
Fighting the flu: 100 years of preparing for pandemics
Although the world’s eyes are currently focused on COVID-19, a network of laboratories has been tracking the emergence and spread of a different virus for seven decades.
18 May 2021
Nomads in lockdown: COVAX reaches the Mongolian steppes
As COVAX vaccines reach the rural Batsumber in Mongolia, livestock herders hope that the loneliness of the pandemic era will soon come to an end.
18 May 2021
Why we support COVAX: UBS and UBS Optimus Foundation
The UBS Optimus Foundation has launched a campaign to help secure funding for the COVAX Advance Market Commitment. Vaccines Work spoke to Tom Hall, the UBS Head of Philanthropy Services to find out why.
17 May 2021
COVID vaccines: some fully vaccinated people will still get infected – here’s why
Reports of fully vaccinated people getting infected with coronavirus shouldn't cause alarm.
17 May 2021
How "camel riders" are helping the COVID-19 vaccine push in Kenya
With tourism hit hard by the pandemic, camel riders in Northern Kenya have repurposed their herds to help spread the word about COVID-19 vaccines, using traditional healers to gain trust in the community.
17 May 2021
The World Isn’t Getting Vaccinated Fast Enough. Here Are 4 Ways to Fix That
In an unprecedented show of global solidarity, the world came together to back COVAX, a unique global solution aimed at making equitable access to COVID-19 vaccines possible.
14 May 2021
COVAX Manufacturing Task Force to tackle vaccine supply challenges
A COVAX Manufacturing Task Force has been established to identify and resolve issues impeding equitable access to vaccines.
14 May 2021
Vaccinator training on smartphone screens amid COVID-19: Another “new normal”?
App-assisted vaccinator training is an approach that shows promise, write the team who ran a Gavi-supported pilot to trial a new screen-based learning mechanism in India. What’s more, amid the pandemic, the flexibility of learning from home,…
14 May 2021
China’s Sinopharm COVID-19 vaccine first to carry a smart label to monitor heat-damage
It is the first vaccine developed by a non-Western country to be approved by the WHO, and is welcome at a time of global vaccine shortages.
14 May 2021
Gavi’s Seth Berkley named one of the world’s greatest leaders by Fortune
Dr Berkley is recognised alongside other world-changing vaccine champions in this year’s list for their part in the fight against COVID-19.
12 May 2021
Kenya completes its first round of COVID-19 vaccinations
After some initial hesitancy amongst health workers, Kenya has successfully rolled out the first batch of COVID-19 vaccine doses.
12 May 2021
As the Spanish flu of 1918-1920 tore through America, a San Francisco mayor bet on the potential of face masks to contain the spread. Then, like today, the demand to mask up met resistance that blended distrust, ideology and gut feeling.
11 May 2021
Covering COVID-19 in Guyana’s ‘Deep South’
The indigenous people adopted measures that were more applicable to the challenges but also their reality. And I tried to illustrate that in my story.
11 May 2021
Mounting evidence suggests COVID vaccines do reduce transmission. How does this work?
Vaccination is likely to substantially reduce virus transmission by reducing the pool of people who become infected, and reducing virus levels in people who get infected.
11 May 2021
Working towards vaccine equity to leave no one behind
Country and community perspectives on realising the targets of the Immunisation Agenda 2030.
10 May 2021
Next Steps for a People’s Vaccine
The Biden administration’s decision to stop opposing a proposed COVID-19 waiver of certain intellectual-property rights under World Trade Organization rules is a welcome move. But ending the pandemic also requires scaling up knowledge and…
10 May 2021
When refusing a COVID-19 vaccine isn’t about hesitancy
The reasons why people may not take a COVID-19 vaccine even when offered can be complex and varied, but they point to the need to tackle them better if we are to improve vaccine coverage.
10 May 2021
COVID-19 vaccines bring relief to Ugandans living with HIV
The pandemic has been tough for the 1.4 million Ugandans living with HIV, but the arrival of the COVID-19 vaccine has brought some welcome relief.
7 May 2021
Expediting COVID-19 vaccination could prevent millions of deaths and save billions of dollars
Increasing vaccination coverage by even 1% can save thousands of lives and millions of dollars in medical and economic costs.
7 May 2021
The rollout of the first phase of the COVID-19 vaccination exercise has not been without its challenges but there is a focus on learning and improving.
7 May 2021
The US adds it support to patent waivers for COVID-19 vaccines
As countries worldwide are suffering from COVID-19 vaccine shortages, sharing intellectual property and know-how, and easing trade bans on the export of raw materials, could ease supply bottlenecks.
7 May 2021
Weather forecasts a ‘life-saving tool against meningitis’
Meningitis affects more than 30,000 people in Africa every year. Scientists use weather data to predict location and scale of impending cases. The prediction helps country-level health services to plan emergency responses.
7 May 2021
COVID vaccines: why waiving patents won’t fix global shortage – scientist explains
Increasing skills and the availability of raw materials would be a bigger boost for vaccine production right now.
6 May 2021
Oxford vaccine professor: rich countries have a moral duty to share their COVID-19 shots
We cannot look back in the future and know we could have done more.
6 May 2021
Emerging lessons from Africa’s COVID-19 vaccine rollout
With 47 African countries now rolling out COVID-19 vaccines and over 17 million doses given on the continent, early insights from Africa’s largest-ever immunization drive offer hope, inspiration and early, yet vital lessons. Here, we shine a…
5 May 2021
Why Indian hospitals are running out of medical oxygen and how to fix it
Investment in bedside oxygen production could make hospitals more resilient in the face of COVID-19.
5 May 2021
What are the most effective ways to improve vaccination rates?
Vaccines are one of our greatest success stories, but vaccination rates for many diseases have been stalling; this has been exacerbated with the disruption caused by Covid-19. Anna Mouser sets out the evidence on what works, and what doesn’t, for…
4 May 2021
Reaching communities with immunisation in South Sudan
To reach zero-dose children in conflict states like South Sudan, social mobilisers like Nyok Daniel are crucial to winning the trust and support of local communities.
4 May 2021
There will be no recovery without equity
The impact of COVID-19 threatens to reverse hard-worn strides in global health. Without immediate investments, we will miss our chance to save lives and help countries recover from the pandemic and build the human capital needed for a resilient…
3 May 2021
Although it is only natural and proper for governments to focus on vaccinating their citizens first, it is important not to lose sight of the big picture. The only way we can beat COVID-19 is to defeat it everywhere, and the best way to do that…
3 May 2021
Why routine immunisation is vital for pandemic preparedness
Trying to control a pandemic can feel like being in a warzone, yet even as we fight COVID-19 we still need to keep one eye on the future and potential emerging pandemics. Dr Velislava Petrova, senior manager in vaccine policy and investment at…
3 May 2021
Are COVID-19 vaccine expiration dates too cautious?
Distributing COVID-19 vaccines has been challenging, meaning in some cases vaccines are being delivered close to their expiration date; but the WHO is urging countries to hold on to the doses while it assesses whether shelf lives can be extended…
3 May 2021
Gavi signs agreement with Moderna to secure doses on behalf of COVAX Facility
The signed advance purchase agreement (APA) is for up to 500 million doses of the COVID-19 vaccine manufactured by Moderna. Supply via the agreement will take place from the second half of 2021 through 2022, with options in place to address the…
30 April 2021
The Pandemic Within the Pandemic
Globally, antibiotic use in hospitals has surged since the start of the COVID-19 pandemic, and over-the-counter sales, legal in many countries, have soared. This is further fueling the global crisis of antimicrobial resistance, as bacteria evolve…
30 April 2021
“Losing my job wasn’t the biggest problem”: A family’s journey through COVID-19 in Ghana
The Safo family, with a seven-year-old son with a number of medical conditions, know all too well what it’s like to have to readjust their lives and limits to accommodate a new reality. The delivery of Ghana’s first batch of COVID-19 vaccines by…
30 April 2021
The vaccinators fighting polio in Rawalpindi
In pockets of vaccine resistance like Fauji Colony in Rawalpindi, Pakistan, children remain at risk of crippling polio. VaccinesWork meets the polio workers going door-to-door to change minds and protect children’s futures.
29 April 2021
Turning a short-term crisis into long-term change
Often, crisis responses and emergency funding do not lead to significant structural changes because their goal is to provide immediate relief, not drive long-term shifts. Immediate crisis relief and long-term structural changes, however, can…
29 April 2021
Understanding vaccine hesitancy: Cha’s story
A new documentary tells a powerful tale of families overcoming every obstacle to protect their children from vaccine preventable disease.
29 April 2021
All aboard! Cameroon’s race to vaccinate every child
Cameroonian health workers are going the distance to reach the remote Island of Manoka on a quest to ensure that no child is left behind.
29 April 2021
Helping children thrive through soap and vaccines
In Uttar Pradesh, India, over 1,000 children die every day from preventable diseases. Gavi’s long-standing partnership with Unilever and Lifebuoy has helped to reach 2.5 million people with essential vaccines and soap, while also leveraging the…
28 April 2021
There are a broad range of different types of vaccine, but one thing they usually have in common is that they are inherently biological. That means that often their ingredients need to be grown.
28 April 2021
Vaccines save millions of lives a year, but what exactly is a vaccine and what goes into making one? And how do we know they are safe? Here, we talk about every aspect of vaccines and why they are so important for our health.
28 April 2021
Exercise boosts immunity and makes vaccines more effective – new study
Meeting the recommended guidelines for physical activity reduces the risk of falling ill and dying of infectious diseases by 37%.
27 April 2021
Reaching zero-dose children in Rajasthan
9.7 million children in 57 Gavi-supported countries remain unvaccinated and at risk. Why are these children missing out? In Bikaner, Rajasthan, VaccinesWork meets two families who simply never landed on the health system’s radar.
27 April 2021
COVID-19 in India: an unfolding humanitarian crisis
Stories of reaching herd immunity were certainly premature.
26 April 2021
An Indian Queen’s “Vaccine Selfie” in Oils
Why a 19th century portrait of three southern Indian noblewomen is “one of the most important scientific pictures in the history of medicine in India.”
26 April 2021
Geneva/New York, 26 April 2021 – While immunization services have started to recover from disruptions caused by COVID-19, millions of children remain vulnerable to deadly diseases, the World Health Organization (WHO), UNICEF and Gavi, the Vaccine…
26 April 2021
The Zero-Dose Child: Explained
Despite decades of progress increasing access to immunisation in lower-income countries, nearly 10 million children still go without basic, routine vaccines every year. Gavi, the Vaccine Alliance is now focusing on reaching these zero-dose…
23 April 2021
Malaria vaccine achieves 77% efficacy in seasonal setting in study of African children
The R21/Matrix-M vaccine is the first to show promise of hitting the World Health Organisation’s target of 75% efficacy against malaria.
23 April 2021
France makes important vaccine dose donation to COVAX
Today, to mark the first year of the creation of the Access to COVID-19 Tools (ACT) Accelerator, President Emmanuel Macron announced that France has begun sharing vaccine doses with COVAX, starting with a first batch of 105,600 doses – with 500,…
23 April 2021
Over half a million doses of COVID-19 vaccines arrived in Angola in March, delivered through the COVAX initiative. VaccinesWork talked to some of the first beneficiaries.
23 April 2021
Why is India’s COVID-19 pandemic skyrocketing?
When the pandemic started, India defied expectations by having a milder outbreak than had been predicted. Now, it is seeing a deadly second wave that is bringing the country’s health system to its knees – so what is behind this, and how much is…
22 April 2021
A deadly cousin of Ebola, Marburg can kill nine out of ten people it infects, and international travel has taken it from Africa to Europe twice in the past 40 years. Will increasing globalisation make this virus more likely to erupt around the…
22 April 2021
Mysterious Ailment, Mysterious Relief: Vaccines Help Some Covid Long Haulers
Scientists who study the post-illness syndrome are taking a close look at patients’ reports of this unexpected benefit of the vaccine.
22 April 2021
Tales from the COVID frontline: An Angolan filmmaker takes on COVID-19
Óscar Gil Pereira is one of Angola’s most celebrated filmmakers. Last year he became one of the 24,000 people in Angola to contract COVID-19. After beating the disease, he is now vaccinated and committed to celebrating the health worker heroes…
22 April 2021
Ivermectin: why a potential COVID treatment isn’t recommended for use
The antiparasitic drug was thought to be a potential treatment for COVID-19, but there isn't sufficient evidence to recommend its use, despite widespread support online.
21 April 2021
What ingredients go into a vaccine?
Vaccines contain active ingredients that trigger an immune response to viruses, bacteria and other pathogens. But in order to work well, it is important that they also contain other key ingredients to keep them safe and effective.
21 April 2021
Are We Risking a Debt Pandemic?
The prospect of recovery from the COVID-19 crisis makes it all the more urgent to have a firm vision of how the burden of public debt can be reduced once the coronavirus has been vanquished. For this reason, every country must work on itself and…
20 April 2021
Resourceful Optimism: Fighting COVID-19 in Afghanistan
The pandemic has strained most countries’ health systems. Afghanistan has faced more hurdles than most.
20 April 2021
Scientists have spent nearly 100 years searching for a better way to give vaccines
We didn’t have to be stuck with needles.
20 April 2021
Serious blood clots “more likely” with COVID-19 infection than vaccine
Study suggests the risk of a serious brain clot is up to ten times higher in people with COVID-19 infections, compared to those receiving a COVID-19 vaccine.
20 April 2021
COVAX: A new standard for global innovation and partnership
COVAX has a critical role to play in ending the acute phase of the pandemic. The initiative could also be a model for how we address some of the most urgent development challenges of our time, from climate change to poverty reduction.
19 April 2021
“A ray of sunshine”: COVAX vaccines reinvigorate health workers in Eswatini
The delivery of vaccines has gone a long way to alleviating the fears and pressure on healthcare workers in Eswatini.
19 April 2021
How long does immunity last after COVID-19 vaccination?
Millions of doses of COVID-19 vaccines are being delivered across the world, but what do we know about how long will immunity last?
19 April 2021
An expert explains how to track coronavirus variants
New Covid-19 variants could potentially jeopardise a lot of the work that has been done so far to contain the pandemic. Sonia Gonçalves explains how genomic surveillance can help us track and contain them.
16 April 2021
Traditional and religious leaders spearhead COVID-19 immunisation in Malawi
Communities often look to their traditional and religious leaders when it comes to advice on how to live. In Malawi, they are stepping to the fore.
16 April 2021
Women on the frontline: delivering COVID-19 vaccines on the Kenya-Somalia border
Al-Shabaab has forced the shutdown of health facilities close to the Somalia border in Northern Kenya. A group of women activists are fighting back, ensuring COVID-19 vaccines reach the most vulnerable.
16 April 2021
COVID-19: does exercising really reduce the risk?
New research suggests people who exercise for 150 minutes a week are half as likely to die from COVID-19 compared to those who are consistently inactive.
15 April 2021
No VIP treatment: Malawi aims for an equitable COVID-19 vaccine roll-out
Since the first consignment of COVAX doses arrived in Malawi in mid-March, vaccination centres like Chileka Health Centre, just outside Blantyre, have recorded enthusiastic turn-out.
15 April 2021
COVID-19 ‘led to rise in stillbirths, maternal deaths’
Maternal health in low- and middle-income countries hit hard by COVID-19. Global review analysed stillbirth, maternal death rates from 17 countries. Maternity care must be prioritised during global health crisis, says report
15 April 2021
Global leaders rally to accelerate access to COVID-19 vaccines for lower-income countries
The “One World Protected” Event, hosted today by the United States and Gavi, the Vaccine Alliance, launched a campaign to raise US$ 2 billion for the global fight against COVID-19.
14 April 2021
As long as there have been vaccines, a vocal minority of public voices have made it their mission to rile up their communities against vaccination. In Montréal, in 1885, those voices were successful – and the results were deadly.
14 April 2021
“I can only run away from death for so long”: Vaccinating Elders in Eswatini
The delivery of COVID-19 vaccines to Eswatini through COVAX means the elderly now have the chance to protect themselves against the disease. VaccinesWork visits a vaccination session in Lobamba.
13 April 2021
Will summer slow the spread of COVID-19? New research sheds light
The seasons can affect transmission of the virus – but this will likely be dwarfed by the impact of public health measures.
13 April 2021
How to Stop the Poverty Pandemic
Experience shows that innovative and evidence-based approaches, when executed well, can dent poverty. With the COVID-19 pandemic threatening to reverse hard-won global gains, the need for policy-relevant research, and for scaling effective…
13 April 2021
What does it take to deliver COVID-19 vaccines?
Ending the COVID-19 crisis hinges on all countries being able to vaccinate their people. A lot goes into getting ready.
12 April 2021
Protecting Uganda’s overstretched health workers through COVAX
Over 50 health workers in Uganda have lost their lives to COVID-19 – a huge toll for a country with just 0.17 doctors per thousand people in some areas. With remaining health workers overworked and vulnerable, some relief has come in the form of…
12 April 2021
The World’s First Vaccination Campaign
At the turn of the 19th century, news of a 1796 medical breakthrough called 'vaccination' started to spread around the world. A fascinating recent book, War Against Smallpox by Michael Bennett, traces the subsequent dissemination of the actual…
12 April 2021
Rolling out COVID-19 vaccines in Rwanda
Kigali – Forty-eight hours after Rwanda received shipments of COVID-19 vaccines, vaccinations began in earnest, with high-risk population given priority. The country plans to vaccinate a third of the population in 2021 and double that figure next…
9 April 2021
Getting from zero to 100% – ensuring every child has routine immunisation
New data shows that investing in getting that first vaccination to children can be a turning point in getting them fully immunised.
9 April 2021
Lockdown mental fatigue rapidly reversed by social contact, study finds
The study found people bounce back from their mental sluggishness soon after emerging from isolation.
9 April 2021
A year of #VaccinesWork in 10 articles answering your most frequently asked questions
To mark one year of #VaccinesWork, we look back at some of the articles that answer the most frequently asked questions about COVID-19 during an unprecedented year for global health.
8 April 2021
Protecting human rights in the COVAX roll-out
The COVID-19 pandemic is the biggest economic and social crisis of a lifetime. Human rights are key in shaping our collective pandemic response, both for the public health emergency and the broader impact on people’s lives and livelihoods.
8 April 2021
What is the blood clotting disorder the AstraZeneca vaccine has been linked to?
The European Medicines Agency has concluded that there is a possible link between AstraZeneca’s COVID-19 vaccine and very rare blood clots. But what are these clots and how great is the risk?
8 April 2021
How geospatial technology is helping Nigeria’s COVID-19 vaccine roll-out
In a huge country like Nigeria, ensuring the right people receive COVAX vaccines is not just a question of how, but where. Could geospatial technology, trialled during previous polio campaigns, make a difference?
8 April 2021
Bacteria 'shuffle' their genetics around to develop antibiotic resistance on demand
A genetic trick called an integron plays an important role in helping bacteria do this.
8 April 2021
Should I get a COVID-19 vaccine if I’ve already had COVID-19?
Natural infection with the coronavirus that causes COVID-19 may not lead to long-lasting immunity, so it is important to get the vaccine as well.
8 April 2021
COVAX reaches over 100 economies, 42 days after first international delivery
The COVAX Facility has now delivered life-saving vaccines to over 100 economies since making its first international delivery to Ghana on February 24th.
7 April 2021
The age of modern vaccines: An Abridged History of Vaccines, Part 2
As the 19th century entered its final quarter, “vaccination” meant one thing: immunisation with cowpox against deadly smallpox. By the end of the 20th century, safe and effective vaccines existed against 26 killer diseases. In the second part of…
7 April 2021
Can a COVID-19 vaccine give me COVID?
Currently approved vaccines incorporate viral proteins or the instructions for making them, but they do not contain any live virus.
7 April 2021
Immunization and vaccination experts from around the world outlined the current state of the world’s vaccination campaigns while addressing the urgent needs and concerns regarding public trust in the efficacy of vaccines; access and challenges.…
6 April 2021
The end of the pandemic is coming – just don't set a date for the party
History tells us that the end of pandemics are rarely – if ever – neat, uncomplicated, or even easy to date.
6 April 2021
The next pandemic: yellow fever?
In the 19th century, yellow fever had taken hold of parts of Europe and the USA, especially the Deep South, killing thousands. Now mostly in Africa and South America, this mosquito-borne disease could spread at any moment, threatening public…
1 April 2021
Arriving at the First Vaccine: An Abridged History of Vaccination, Part 1
As early as the 1500s, efforts to halt the spread of smallpox included risky procedures designed to trigger immunity. By the 1800s, these methods – collectively termed “variolation” – had been supplanted by the earliest example of a new, safer…
1 April 2021
How does resistance to disinfectants happen? We're on the road to answering the question
The increased use of disinfectants could allow for the development of bacterial strains which are resistant to disinfectants.
1 April 2021
Somalia rolls out vaccines for COVID-19
On 15 March 2020, Somalia received 300 000 doses of Oxford AstraZeneca vaccines from the COVAX Facility to protect frontline workers and elderly people with chronic health conditions from COVID-19. The World Health Organization (WHO) hears…
1 April 2021
Relieved and hopeful: Reflections after my first COVAX vaccine
In March, Mukami received her first COVAX vaccine dose. As a woman in her 60s living in Kenya, she has priority access to COVAX vaccines, alongside other high-risk groups like health care workers and people with underlying diseases. Here she…
31 March 2021
What does water mean to the world?
On 22 March 2021, the world marked World Water Day, with the theme for this year’s celebration being “valuing water.” What can the long history of water’s connection with health teach us about its true value to the world?
31 March 2021
How Can Covid Vaccines Be Safe When They Were Developed So Fast?
Experts say there’s nothing new about the research underpinning the covid vaccines and that they were tested in more participants than many other approved vaccines.
31 March 2021
Why we need to share vaccine doses now and why COVAX is the right way to do it
Covid-19 vaccination efforts are picking up worldwide, bringing hopes of returning to a more normal life. Vaccines are now starting to reach countries across the globe through the COVAX initiative, set up to promote equitable access to vaccines…
30 March 2021
We know hand dryers can circulate germs through the air. Why are they still used everywhere?
What side are you on, paper or dryer? In either case, here's the bottom line on what to do after using the toilet.
30 March 2021
Patient Zero: Understanding how new coronavirus variants emerge
By understanding the circumstances that make viral evolution more likely, we stand a better chance of staying a step ahead.
30 March 2021
The COVAX Humanitarian Buffer Explained
COVAX was designed to ensure the most vulnerable in every country get access to COVID-19 vaccines. But what about people in conflict zones or humanitarian settings that can’t be reached by government vaccination campaigns? Last week Gavi approved…
30 March 2021
COVID-19 vaccines: assessing country readiness
The key insights from the assessments to date present a high-level snapshot of country readiness to deploy COVID-19 vaccines based on initial findings from ongoing assessments in 128 countries.
29 March 2021
A year of #VaccinesWork in 10 articles looking at vaccine-preventable diseases other than COVID-19
To mark the first anniversary of #VaccinesWork, we look back at some of the most read articles on diseases other than COVID-19 during an unprecedented year for global health.
29 March 2021
5 things to know after you’ve had a COVID-19 vaccine
As more and more people get vaccinated against COVID-19, some are worrying about how ‘normal’ their side effects are. Here’s what you need to know.
29 March 2021
Going universal: The search for an all-in-one coronavirus vaccine
Instead of working to make vaccines against each unique coronavirus or variant, what if we could provide broad protection across the field through an all-in-one coronavirus shot?
29 March 2021
United States to host launch event for Gavi COVAX AMC 2021 investment opportunity
The virtual event will bring together world leaders, the private sector, civil society, and key technical partners to galvanize resources and commitment to the Gavi COVAX Advance Market Commitment (AMC).
26 March 2021
We must better protect wildlife to prevent future pandemics
Wuhan investigation points to wildlife as likely source of COVID-19. Climate change and illegal trade are increasing risk of zoonotic disease transmission. Wildlife protection, surveillance of zoonosis are key to early detection of ‘spillover…
26 March 2021
“We’re closer to getting some normalcy back in our lives”: COVAX gets underway in Ghana
Ghana became the first African country to receive vaccines through the COVAX initiative in February. Meet one of the nurses spearheading the vaccination effort.
26 March 2021
The next pandemic: H5N1 and H7N9 influenza?
More than 100 years after the 1918 Spanish influenza pandemic, type A influenza virus not only poses one of the largest threats to the modern world, but the risk of spill-over of avian influenza from poultry to humans is growing.
26 March 2021
What we learned from tracking every COVID policy in the world
For one year, 600 people tracked 20 types of coronavirus restriction in 186 countries – here's what they found out.
25 March 2021
The growing threat of pandemics
Whilst COVID-19 caught the world off guard, the speed at which it spread and the extent of its impact on people’s lives came as a great shock to most. However, some were not surprised at all.
25 March 2021
Keeping It Cool: A visit to Ghana’s national vaccine storage facility
Ghana became the first African country to receive COVAX doses in February, kicking off a mammoth logistical effort in the country to get these doses to the frontline workers that need them. #VaccinesWork spoke to the cold chain experts making it…
25 March 2021
Africa’s had a 30% rise in COVID-19 cases in the second wave
The continent had a milder first wave than the rest of the world, but research suggests that relaxed public health measures led to the coronavirus rebounding with a vengeance the second time around.
24 March 2021
A year of #VaccinesWork in 10 articles from around the world
To mark the first anniversary of #VaccinesWork, we look back at some of the most-read articles on how countries have been navigating COVID-19 during an unprecedentedly challenging year for global health.
24 March 2021
Why is a global Covid-19 vaccine rollout vital?
The Covid-19 pandemic is global, and to bring the pandemic to a close, a collaborative, global approach is needed. But why is it so important that all countries have access to vaccines as soon as possible?
24 March 2021
These results can help allay previous concerns in Europe about a lack of trial data for older people.
24 March 2021
COVID-19 vaccines: could a squirt up the nose be just as good as a shot in the arm?
There are several COVID-19 vaccines being used around the world, but all need to be injected and some need ultra-cold refrigeration. Could next-generation intranasal vaccines be a quicker and easier way of protecting ourselves?
24 March 2021
How far away are we from a new TB vaccine?
Tuberculosis kills millions of people each year, but several recent advances in vaccine development are providing fresh hope.
23 March 2021
The next pandemic: Chikungunya?
The tiger mosquito that carries the chikungunya virus is now moving into new habitats in Europe and America thanks to climate change. This means the once tropical disease could soon become a global pandemic threat.
23 March 2021
An Ounce of Pandemic Prevention
The global response to the coronavirus pandemic, for all its flaws, has yielded impressive results by ignoring traditional bureaucratic and sectoral silos. That should spur us to raise our ambitions for global public health, with an emphasis on…
23 March 2021
Why COVID-19 makes you lose your sense of smell and how to get it back
The virus appears to attack support cells at the back of the nose, but “smell training” may help people to recover their missing sense.
23 March 2021
What is Africa’s vaccine production capacity?
Accra, 18 March 2021 – COVID-19 vaccination in Africa is gathering pace, with more than 7 million doses so far administered. But the continent received vaccines later than other regions of the world and in limited quantity. A few weeks after…
22 March 2021
“I serve my nation through my profession”: Community vaccinators in Afghanistan
Community vaccinators go where fixed health centres can’t reach. In Afghanistan, that means fighting Taliban injunctions, entrenched gender imbalances and difficult terrain, all to ensure the nation’s children are protected.
22 March 2021
Tariah Adams: on tap for women and girls’ right to water, sanitation and hygiene
In today’s blog post, we’re featuring a fierce and passionate female WASH advocate from Nigeria. Tariah Adams, a Senior Communications and Advocacy Officer for White Ribbon Alliance Nigeria and campaign mobilizer, she has a personal interest in…
22 March 2021
At the end of the year 2019, we created an elaborate 2020 plan for our projects at Beyond the Classroom Foundation. As we got closer to our second project scheduled for the end of March, the government imposed a lockdown, banning all public…
22 March 2021
COVID shows infectious disease is our greatest threat to global security
Unlike traditional security threats, infectious disease can’t be solved through sanctions, military posturing, deterrence or bilateral diplomacy, but rather through scientific collaboration, long-term investments in global health and resilient…
19 March 2021
Ebola has so far only affected African countries, and occasional cases outside of the continent have been rapidly contained. But the virus could mutate to spread more easily between people, making it more of a pandemic threat.
19 March 2021
A year of #VaccinesWork in 10 articles celebrating women in global health
To mark the first anniversary of #VaccinesWork, we look back at some of the most read articles on COVID-19 during an unprecedented year for global health.
19 March 2021
So far, homeschooling has been trial and error because it’s difficult to keep the twins calm and engaged for long periods of time. We have no fixed curriculum and use online educational programs as a guide.
18 March 2021
“We’ll all be fine”: COVID-19 vaccines arrive at Korle-Bu Teaching Hospital, Accra
After a difficult year, the vaccination roll-out is underway at Ghana’s premier medical facility, where health workers dare to hope that things can go back to normal.
18 March 2021
John Nkengasong on Africa's Vaccine Game Plan
John Nkengasong is the Director of the Africa Centers for Disease Control and Prevention. He is also the WHO special envoy for Africa. John spoke to CovidHQAfrica desk about a range of issues including his vision for the vaccines in Africa, and…
18 March 2021
No "us versus them": why equitable inclusion of all migrants in COVID-19 vaccine plans is essential
COVID-19 has demonstrated that viruses not only know no borders, but they also do not discriminate based on immigration status. Failing to take migrants into account in our vaccination efforts would hamper the effectiveness of these campaigns and…
17 March 2021
A year of #VaccinesWork in 10 COVID-19 articles
To mark the first anniversary of #VaccinesWork, we look back at some of the most read articles on COVID-19 during an unprecedented year for global health.
17 March 2021
Should I invest in a pulse oximeter?
Sales of medical devices that measure the oxygen saturation of blood are booming thanks to the COVID-19 pandemic. But are they worth the investment?
17 March 2021
Dormant virus reawakening may have triggered Ebola outbreak
Genetic sequencing has linked the recent outbreak of Ebola disease to a survivor of the 2014-16 West Africa epidemic, meaning the virus could have laid dormant in one survivor for over five years. What does this mean for our efforts to control…
17 March 2021
Nigeria rallies over 7,000 traditional leaders against COVID-19
Abuja, 12 March 2021 – As the second wave of COVID-19 affects the global health and economic community, the World Health Organization (WHO) is supporting government to engage strategic stakeholders as part of concerted efforts to reverse the…
16 March 2021
How can supply keep up with demand for COVID-19 vaccines?
With the historic global roll-out of COVID-19 vaccines in full swing, bottlenecks in the supply chain are inevitable as manufacturing output tries to keep pace with demand. A manufacturing supply chain summit last week outlined potential…
16 March 2021
Vaccine Altruists Find Appointments for Those Who Can’t
An army of volunteers help people who otherwise would have had difficulty securing a covid vaccination because of cumbersome computer or telephone registration systems.
16 March 2021
Does the AstraZeneca COVID-19 vaccine really cause blood clots?
Various countries have halted the use of the Oxford-AstraZeneca vaccine, while reports of blood clots are investigated. Here’s what we know so far.
15 March 2021
Battling misinformation wars in Africa: applying lessons from GMOs to COVID-19
For anyone who has worked on crop improvement in Africa over the last three decades, the flood of misinformation around vaccines evokes an eerie sense of déjà vu.
15 March 2021
The next pandemic: Nipah virus?
Nipah virus can kill as many as three out of four people it infects. Since the fruit bat that carries the virus often comes into contact with humans, here we explain why the development of drugs and vaccines for the disease is becoming…
12 March 2021
Why do some people with COVID-19 get sicker than others?
Our immune systems are supposed to defend us from invading pathogens but, in the case of COVID-19, an immune overreaction may be to blame for severe illness.
12 March 2021
'Like being hit with a cricket bat’: A doctor’s battle with long COVID
Dr Paul Garner, a British infectious disease expert at the UK’s Liverpool School of Tropical Medicine caught COVID-19 early in 2020, and then developed Long COVID. Here, he talks frankly with Gavi about his experiences, how he recovered and how…
12 March 2021
When can children get the COVID-19 vaccine? 5 questions parents are asking
COVID-19 vaccine testing on children is just getting started, and only in adolescents.
12 March 2021
Why Ebola is back in Guinea and why the response must be different this time
The virus is always present in nature and when circumstances allow, it may jump from one species to another.
11 March 2021
Since COVID-19 was declared a global pandemic, many countries around the world imposed some form of quarantine to control its spread. What can the history of quarantine teach us about isolation and lockdowns now?
11 March 2021
Diphtheria may resurface as a ‘major global threat’ study warns.
Researchers identify bacterial variants that may be evolving resistance to antimicrobials and vaccines.
11 March 2021
Ten lessons from Ogun State - from first COVID-19 case in Nigeria to building a resilient response
Vivianne Ihekweazu (Lead writer): On the day marking one year since the first COVID-19 case was reported in Nigeria, this article reflects on the experience and lessons learnt from the Honourable Commissioner for Health, Dr. Tomi Coker as she led…
10 March 2021
Don’t overlook the most important metric for Johnson & Johnson’s Covid-19 vaccine
Overall efficacy is just one metric.
10 March 2021
At the end of the tunnel: the virus – then the vaccine – reach a remote Himalayan valley
For the people of Lahaul, the opening of a new high-altitude tunnel ends years of wintertime isolation – and opens a vital route of access for COVID-19 vaccines.
10 March 2021
AstraZeneca vaccine: careless talk has dented confidence and uptake in Europe
Stockpiles of this vaccine are going unused in France and Germany, and unfounded criticism of it may be partly to blame.
9 March 2021
Keeping the Cold Chain Cold: The Importance of Maintenance
This is the third in a three-part series highlighting key lessons learned since the launch, four years ago, of the Cold Chain Equipment Optimization Platform (CCEOP), established by Gavi, the Vaccine Alliance, to ensure optimal cold chain…
9 March 2021
Private sector innovation meets public health expectations
This is the second in a three-part series highlighting key lessons learned since the launch, four years ago, of the Cold Chain Equipment Optimization Platform (CCEOP), established by Gavi, the Vaccine Alliance, to ensure optimal cold chain…
9 March 2021
Breaking the glass vial: Women at the forefront of COVID-19 vaccine
Leaders in global health have been working on COVAX – a global initiative to ensure the fair distribution of COVID-19 vaccines. Some of the top jobs are held by a diverse group of women, so in honour of International Women's Day we'd like to…
8 March 2021
International Women's Day 2021
For this year's International Women's Day VaccinesWork has interviewed a number of women leaders and front line workers who represent this year's IWD theme: #ChooseToChallenge
8 March 2021
International Women’s Day 2021: “Women come to me and I guide them”
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Nighat Rani, a vaccinator in Pakistan, shows how her work rests on a bedrock of female empathy and understanding…
8 March 2021
International Women’s Day: Chizoba Wonodi on the importance of a good mentor
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Professor Chizoba Wonodi, Founder of Women Advocates for Vaccine Access in Nigeria and Country Director at the…
8 March 2021
International Women’s Day: Quarraisha Abdool Karim on the fight against HIV
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Professor Quarraisha Abdool Karim, epidemiologist and associate scientific director for CAPRISA – the Centre for…
8 March 2021
International Women’s Day: Heidi Larson and the fight against vaccine hesitancy
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Professor Heidi Larson, Founding Director of the Vaccine Confidence Project, explains how gender can affect…
8 March 2021
International Women’s Day: Caring for Everyone: an ASHA worker’s COVID-19 story
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Rathnamma P, an 'ASHA' in Bengaluru, India, explains how the country's army of one million female community health…
8 March 2021
International Women’s Day: Anuradha Gupta on ‘choose to challenge’
This International Women’s Day Vaccines Work is hosting a series of interviews with inspirational women from across the world. Here Anuradha Gupta, Gavi’s Deputy CEO, explains what ‘choose to challenge’ – this year’s IWD theme – means to her.
5 March 2021
The value of COVID-19 vaccines in children: Roadmap for a safer world
To make the world safe from COVID-19, we need everyone vaccinated, including children. To get back to normality, we also need vaccinated adults, ongoing safety measures, safe re-opening of schools, access to all recommended vaccines – and…
5 March 2021
A little less hesitation, a little more action - Elvis and the polio vaccine
As political and public health leaders across the world work to encourage people to get vaccinated against COVID-19, what can they learn from the King of Rock ‘n’ Roll getting jabbed?
5 March 2021
The ins and outs of Kenya's COVID-19 vaccine rollout plan
Reaching the goals of the plan requires the best possible interaction between public and private -for profit and not-for-profit - healthcare sectors.
4 March 2021
Drone delivered COVID-19 vaccines take to the air
The first deliveries of up to 2.5 million doses of COVAX vaccines by autonomous drone began this week in Ghana.
4 March 2021
What is COVID-19 vaccine efficacy?
Several vaccines that have become available have shown different levels of efficacy. So what is vaccine efficacy? Dr Lee Hampton, a paediatrician and medical epidemiologist with Gavi, the Vaccine Alliance, explains.
3 March 2021
Scientists edge closer to a universal flu vaccine
A vaccine that apparently protects animals against multiple strains of flu has been created by tethering a relatively unchanging part of the surface proteins found on the virus to nanoparticles.
3 March 2021
How to make sure COVID-19 vaccines reach as many people as possible
As more COVID-19 vaccines become available, countries the world over are now faced with the daunting task of carrying out mass vaccinations. Here, one expert explains how her organisation is supporting rollouts in the US and offers insights into…
3 March 2021
Why I volunteered to be infected with coronavirus
Most people have been doing everything they can to avoid getting COVID-19, but in the coming days British history student Jacob Hopkins has chosen to be deliberately infected with SARS-CoV-2 as part of the world’s first Challenge Trial. He…
2 March 2021
COVID vaccines: how to make sense of reports on their effectiveness
Real-world studies of vaccines aren't directly comparable with clinical trials, but their results are still good news.
2 March 2021
5 reasons to believe the COVID-19 pandemic might be slowing down
COVID-19 cases are falling week on week, so can we allow ourselves to be hopeful?
1 March 2021
The first COVAX vaccinations begin
COVID-19 vaccination campaigns using COVAX-funded doses commenced today in Côte d’Ivoire and Ghana, the first global rollout.
26 February 2021
Country readiness for COVID-19 vaccines
This article is part of a series of explainers on vaccine development and distribution. Learn more about vaccines – from how they work and how they’re made to ensuring safety and equitable access – in WHO’s Vaccines Explained series.
26 February 2021
COVAX vaccines take to the air by drone
Ghana is not only the first country to receive a shipment of COVAX vaccines, but it will be the first to broaden its reach by delivering them by drone. The new partnership with Zipline and UPS Foundation will see 2.5 million doses delivered this…
26 February 2021
COVID-19: what happens if some countries don't vaccinate?
Even those that live in areas where the population has already been vaccinated would not be totally protected if the virus mutates elsewhere.
25 February 2021
Planning for Success: Project Management Teams for the CCEOP
The first in a three-part series of blogs highlighting key lessons learned since the launch, four years ago, of the Cold Chain Equipment Optimization Platform (CCEOP), established by Gavi, the Vaccine Alliance, to ensure optimal cold chain…
25 February 2021
How Roald Dahl became a passionate vaccine advocate
Roald Dahl's daughter Olivia died of measles aged seven.
24 February 2021
Why vaccine side effects might be more common in people who've already had COVID-19
Minor side effects are a normal sign that the immune system is mounting a protective response following vaccination, although they aren’t universal.
24 February 2021
Ebola strikes West Africa again: key questions and lessons from the past
Countries in the West Africa region are in a very different position to seven years ago. They now have the experience of the past as well as new tools to tackle Ebola.
23 February 2021
Real-world data supports the use of AstraZeneca vaccine in older individuals
Vaccine data from Scotland provides reassurance that the Oxford-AstraZeneca and Pfizer-BioNTech vaccines will significantly reduce hospitalisations and deaths from COVID-19 among older people after the first dose.
23 February 2021
African countries have an advantage in rolling out Covid-19 vaccines
The continent is one of the most experienced regions in the world in dealing with disease outbreaks.
23 February 2021
Why do antibodies fade after a COVID-19 infection, and will the same thing happen with vaccines?
Maintaining antibodies in the blood requires creating certain long-lasting immune cells – but this doesn't always happen.
23 February 2021
Will we ever get rid of COVID-19?
The pandemic won’t last forever, but the virus that causes COVID-19 might. Here we look at what we can expect over the next couple of years in a Q&A with Dr Lee Hampton, pediatrician and medical epidemiologist at Gavi.
22 February 2021
How long does immunity last against Ebola?
The tracking of antibodies in Ebola survivors suggests they wax and wane, which could make vaccine booster shots necessary.
22 February 2021
Saving the planet from catastrophic climate change will require not only a dramatic increase in funding for clean-energy research and development. We need innovation in policy just as much as in technology.
22 February 2021
The $4 trillion economic cost of not vaccinating the entire world
The world's most advanced economies will incur half the total costs associated with a failure to vaccinate poorer nations, which could exceed $4 trillion if only half their citizens are inoculated.
19 February 2021
Could a universal coronavirus vaccine future-proof our response?
With three major coronavirus outbreaks in the last two decades – first SARS-CoV, then MERS-CoV, and now SARS-CoV-2 that causes COVID-19 – another outbreak is inevitable. Scientists are calling for the world to step up the search for a universal…
19 February 2021
What are COVID-19 challenge trials and why do we need them?
A new trial about to start in the UK will deliberately infect people with the virus that causes COVID-19 – if we have vaccines already, why do we need this?
19 February 2021
Tackling pandemic threats proactively
If we are to minimize the impact of future disease outbreaks, we must recognize the importance of immunization and invest in preemptive vaccine development, writes Tim Keys.
19 February 2021
100 years and counting of mask wearing in Japan
As wearing face masks in public becomes the new normal across the world, what can we learn from a country like Japan, where this has been a long-established practice?
18 February 2021
Grab, jab and release: keeping rabies off the streets of Goa
The global effort to contain COVID-19 risks disrupting campaigns against other diseases. Will the fight to control the deadly rabies virus in India be among them?
18 February 2021
The largest global rollout of vaccines in history just got one step closer
The World Health Organization has given the Oxford-AstraZeneca vaccine an Emergency Use Listing, passing an important milestone before the first delivery of COVAX vaccines worldwide.
18 February 2021
Vaccines against SARS-CoV-2 will have side effects – that's a good thing
The side effects of new SARS-CoV-2 vaccines are a result of immune system activation. While uncomfortable, they are both normal and expected. They are a sign that the vaccine is working.
18 February 2021
The G7 has an opportunity to demonstrate global leadership in the COVID-19 pandemic by making the success of the international COVAX vaccine-access facility its top priority. Global solidarity is not only morally right, but also offers the…
17 February 2021
How have Covid-19 vaccines been made quickly and safely?
Unprecedented international cooperation and focus have led to multiple effective and safe Covid-19 vaccines in less than a year, and created a blueprint for future vaccine development. Here's how
17 February 2021
Why having COVID-19 data on men and women is critical
COVID-19 deaths differ among men and women but the differences are not reported. A project is building sex-aggregated data on COVID-19 globally. Such data is key to developing effective solutions to fight COVID-19.
16 February 2021
Side Effects and COVID-19 Vaccines: What to Expect
It’s totally normal to experience side effects from COVID-19 vaccines. Here’s what you need to know.
16 February 2021
Could new outbreaks put Ebola vaccines to the test once again
Guinea is having its first Ebola outbreak since 2016, when West Africa experienced the biggest outbreak ever seen. Could the vaccine that contained previous outbreaks soon be redeployed?
16 February 2021
COVAX Statement on WHO Emergency Use Listing for AstraZeneca/Oxford COVID-19 Vaccine
Geneva / New York / Oslo – 15 February 2021 The Coalition for Epidemic Preparedness Innovations (CEPI), Gavi, the Vaccine Alliance (Gavi) and the World Health Organisation (WHO), as co-leads of the COVAX initiative for equitable global access to…
16 February 2021
When will the world be vaccinated against Covid-19?
With the first Covid-19 vaccines in short supply, how do governments decide who gets a vaccine first?
16 February 2021
Is the colonial era still impacting people’s health today?
A new study suggests that historical traumas from the French colonial era may be associated with less trust in modern medicine and lower vaccination rates today.
15 February 2021
COVID-19 variants are not going away, but vaccines may help make that OK
Clinically significant SARS-CoV-2 variants are likely to be here to stay, but multiple COVID-19 vaccines still have a role to play.
15 February 2021
All roads lead to Ocean: how cancer treatment works in Tanzania
In Tanzania, the Ocean Road Cancer Institute is doing its part to ensure that people across the country can receive cancer treatment and care, regardless of their ability to pay.
15 February 2021
Gavi’s CEO explains how the COVAX Advance Market Commitment mechanism will make COVID-19 vaccines available to lower-income countries.
15 February 2021
Maina Modu is the programme manager for Routine Immunisation in Borno State, working with the State Primary Health Care Development Agency (SPHCDA). He coordinates the state emergency routine immunisation coordination centre activities.
15 February 2021
Tackling the COVID Hunger Crisis
The choice facing world leaders is simple: act now to tackle the hunger crisis, or pay a much higher price later. Immediate action will be cheaper and save more lives than responding only after multiple famines have taken hold and a generation’s…
12 February 2021
Community Health Workers, Often Overlooked, Bring Trust to the Pandemic Fight
As the pandemic brings long-standing health disparities into sharper view, community health workers are coming to the forefront in the public health response. This fast-growing workforce help fill the gaps between health care providers and low-…
12 February 2021
A leap forward in vaccine technology
By building on the lessons learned in 2020, it should be possible in the long term to compress vaccine development timelines still further. That would allow healthcare systems to stamp out disease outbreaks much earlier and save many more lives…
12 February 2021
Do COVID-19 variants mean that we need a booster shot for our booster?
Oxford scientists are already working on an updated version of their COVID-19 vaccine to ensure people remain fully protected against new variants of SARS-CoV-2. But how would these be delivered and how often would they be needed?
12 February 2021
WHO experts have just recommended the Oxford-AstraZeneca vaccine: here’s what they found
The recommendations offer reassurance amid concern over whether some vaccines are as effective against new variants.
12 February 2021
The Silent Pandemic of Antibiotic Resistance
Antibiotic resistance has been a slow-growing scourge, fueled in part by relatively weak political support for implementing national action plans and surveillance systems. Because the problem is essentially the result of multiple systems failures…
11 February 2021
Reaching Pakistan’s zero-dose children during the COVID-19 pandemic
In Islamabad’s slums, Gavi-supported Civil Society Human and Institutional Development Programme is ensuring that parents know that their children can be vaccinated safely by following COVID-19 guidelines.
11 February 2021
All aboard the vaccine minibus: getting immunisation back on track in Pakistan
In Pakistan, a life-saving game of immunisation catch-up is underway after the COVID-19 emergency forced over a million children to miss out on routine vaccinations.
11 February 2021
How important are surfaces in the transmission of COVID-19?
Contaminated doorknobs and packaging probably aren’t the main way the coronavirus spreads. But don’t throw away the hand gel and cleaning products just yet.
10 February 2021
Will coronavirus really evolve to become less deadly?
The coronavirus is evolving, but which path it will take is far from certain.
10 February 2021
The world's last smallpox patient
Smallpox was one of the deadliest diseases in the world, but it’s the only one in history to have been eradicated globally. One Somali man sat on the frontline of this effort and can inspire the world today as we battle yet another devastating…
9 February 2021
What are 'adverse events' and 'emergency use authorisation' in relation to vaccination?
While vaccines are the safest way to prevent the spread of infectious disease, a tiny proportion of those vaccinated may experience an adverse event. Here, we explain how often this happens and why.
9 February 2021
Here’s how we could stop antimicrobial resistance becoming the next pandemic
Antimicrobial resistance was already a major global health threat, but now the potential increase in the use of antibiotics in response to the pandemic could exacerbate the problem and threaten a potentially even bigger global crisis.
9 February 2021
What’s the most effective face mask for preventing COVID-19 transmission?
Face coverings have become a standard feature of pandemic life, but which mask is best for everyday use, and how should you take care of it?
9 February 2021
Protecting Lower-Income Countries with COVID-19 Vaccines Requires Global Solidarity
The medical and moral imperative for equitable access to COVID-19 vaccines is why COVAX was created. Co-led by Gavi, the Vaccine Alliance, together with the World Health Organization (WHO) and the Coalition for Epidemic Preparedness Innovations (…
8 February 2021
4 things about mRNA COVID vaccines researchers still want to find out
Researchers are already working to improve the current crop of mRNA vaccines. Hopefully this will help them become more practical and affordable for the entire world, not just first-world countries.
8 February 2021
How COVID-19 is altering cold and flu seasons
Pandemic restrictions and wider use of flu vaccines may have explained 2020’s record low cases of seasonal flu, but will the picture look like in tropical countries with year-round flu?
8 February 2021
COVAX Statement on New Variants of SARS-CoV-2
The emergence of variants of SARS-CoV-2, the virus that causes COVID-19, serve as a powerful reminder that viruses by their very nature mutate, and that the scientific response may need to adapt if they are to remain effective against them.
8 February 2021
How the Oxford-AstraZeneca vaccine could still help the battle against the COVID-19 variant
Research suggesting that one of the COVID-19 vaccines provides only minimal protection against mild-moderate infection caused by the 501.Y.V2 variant has raised concerns. But this doesn’t mean it won’t prevent severe disease and deaths.
5 February 2021
Eliminating cervical cancer depends on global effort to ensure supply meets demand
Global access to HPV vaccine is vital, particularly in lower-income countries. Lessons learned from HPV roll-out could boost uptake of COVID-19 vaccines.
5 February 2021
Why even a low efficacy COVID-19 vaccine could still be extremely useful
Efficacy rates for COVID-19 vaccines are higher than many scientists had dared dream of, but even if they prove less effective in real life, or in the face of new variants, they could still unlock normal life.
5 February 2021
Who can’t have a COVID-19 vaccine?
The currently available coronavirus vaccines have been tested on adults of various ages, as well as those with long-term conditions, and appear to be safe. But there are a few groups who should avoid being vaccinated for now.
5 February 2021
Why do measles survivors get sicker?
Scientists wanted to find out about the long-term effect of measles on the immune system. Scientific article for students.
4 February 2021
The Oxford-AstraZeneca COVID-19 vaccine could stop transmission of the virus
Several COVID-19 vaccines may have now demonstrated their ability to prevent disease, but it was still not clear whether any could stop the virus being passed on. Now however a preliminary study suggests that some might also be able to reduce…
4 February 2021
Can the world ever be cervical cancer-free?
As World Cancer Day approaches amidst the COVID-19 pandemic, it’s now more important than ever to ensure continued access to HPV vaccines to eliminate cervical cancer around the world.
4 February 2021
Women Leaders in Polio Eradication: Dr. Alda Morais Pedro De Sousa
Dr. De Sousa has spent more than twenty years charting the highs and lows of polio eradication in Angola.
4 February 2021
How safe are COVID-19 vaccines?
Given the speed at which COVID-19 vaccines have been developed, it is understandable that people want to know whether they are safe. So what measures have been put in place to ensure the safety of these new vaccines?
3 February 2021
Everything we know about Johnson & Johnson’s single-dose Covid-19 vaccine
The single-dose vaccine showed promising results in preliminary data from a phase 3 clinical trial.
3 February 2021
The next step: Lifesaving typhoid conjugate vaccines reach Punjab province, Pakistan
Punjab province introduces typhoid conjugate vaccine, taking the next step in protecting children from typhoid in Pakistan.
3 February 2021
How India is using a digital track and trace system to ensure COVID-19 vaccines reach everyone
A system originally designed to do real-time monitoring of vaccine supply chains in India has now been adapted to help ensure COVID-19 vaccines reach as many people as possible.
3 February 2021
Results from Novavax vaccine trials in the UK and South Africa differ: why, and does it matter?
The results indicate that the vaccine efficacy in the UK was 89% for individuals who received at least two doses of vaccine. In South Africa, the vaccine efficacy was 60% in people without HIV.
3 February 2021
COVAX publishes first interim distribution forecast
Geneva/Oslo/New York, 3 February 2021 – The Coalition for Epidemic Preparedness Innovations (CEPI), Gavi, the Vaccine Alliance and the World Health Organisation, as co-leads of the COVAX initiative for equitable global access to COVID-19 vaccines…
2 February 2021
With the World Health Organization inviting COVID-19 vaccine manufacturers to submit their candidates for evaluation, we examine the process from submission to Emergency Use Listing.
2 February 2021
COVID-19 variant found in Brazil ‘spreads faster’
Manaus variant spreads faster and could carry higher risk of infection. Researchers believe new variant spread from Brazil to Asia. Fast, widespread vaccination is best way to slow down mutations.
2 February 2021
When Your Chance for a Covid Shot Comes, Don’t Worry About the Numbers
When getting vaccinated against covid-19, there’s no sense being picky. You should take the first authorized vaccine that’s offered, experts say.
1 February 2021
Q&A: Tales from the COVID frontline – coping with the pandemic on a psychiatric ward
Irene Baker* is a care assistant at a psychiatric hospital in England. She describes the challenges of caring for mentally ill patients during the second wave of the COVID-19 pandemic.
1 February 2021
The body's fight against COVID-19 explained using 3D-printed models
A biologist explains what proteins do in viruses, how they interact with human cells, how the vaccine delivers mRNA into the cell and how antibodies protect us.
1 February 2021
New GPEI Director Aidan O’Leary takes helm of global polio effort
In a special one-off interview, PolioNews (PN) talks to both Aidan O’Leary (A-O’L) and Michel Zaffran (MZ) about the future of polio eradication.
29 January 2021
Pfizer and Moderna’s COVID-19 vaccine candidates have turned the vaccine cold chain into hot news. But what is a cold chain? How does it work? And what does it have to do with equity?
29 January 2021
4 of our greatest achievements in vaccine science (that led to COVID vaccines)
We've gone from a novel virus to several COVID-19 vaccines in less than a year. Here's what we've learned from earlier vaccines to allow this to happen.
29 January 2021
COVAX Supply Forecast reveals where and when COVID-19 vaccines will be delivered
COVAX is forecasting it will roll out over 2 billion COVID-19 vaccine doses in 2021. What does that mean for the world’s poorest countries?
29 January 2021
How much of an impact do vaccines really have?
The world’s most comprehensive study reveals all! A new study looking at the impact of vaccinations in 98 countries over the past 20 years concludes that 37 million people are alive today thanks to vaccines.
28 January 2021
Will the Covid-19 vaccine work on the new variants?
Scientists are working to understand what mutations of the virus mean for inoculation strategies.
28 January 2021
How will COVID-19 vaccines be approved for use in Australia?
Australia is set to get the green light to roll out the Pfizer vaccine any day now. There is a complex process behind this.
28 January 2021
The state of the world’s sanitation
To achieve universal sanitation, we need greater investment and higher rates of sanitation coverage.
28 January 2021
Is there an economic case for global vaccinations?
New research adds to the argument that the global distribution of COVID-19 vaccines is the most optimal solution for a global economic recovery.
27 January 2021
What if I don’t get my second Covid-19 vaccine dose on time?
Don't panic if a second dose isn't available exactly when you need it.
27 January 2021
In Zimbabwe, Friendship Bench, a community-based approach is providing solutions to people struggling with their mental health during this pandemic.
27 January 2021
The importance of blood markers in assessing vaccine efficacy
If vaccine efficacy can’t be assessed through placebo-controlled trials in future, how can we know if they are effective?
26 January 2021
Hesitancy over new COVID-19 vaccines doesn’t seem likely to affect uptake
The initial concern that nervousness over the new vaccines would slow uptake doesn’t seem to have become a reality in the early days of COVID-19 immunisation, although it will be critical to maintain vaccine confidence suggests an Ipsos poll.
26 January 2021
South African scientists who discovered new COVID-19 variant share what they know
Scientists have observed that 501Y.V2 has quickly become "dominant" among multiple variants that have been circulating in the South African population.
26 January 2021
Door to Door in Miami’s Little Havana to Build Trust in Testing, Vaccination
It’s time-consuming but worthwhile: Residents respond to messages about Covid testing and vaccines when outreach teams speak their language and make a personal connection.
25 January 2021
COVID-19 impact ‘vastly underestimated’ in African countries
Zambian data challenges the assumption African populations may have been spared from COVID-19.
25 January 2021
How accurate are lateral flow tests?
Will these rapid tests really allow us to lower our guard during the pandemic?
25 January 2021
COVID-19 and the cost of vaccine nationalism
Without a vaccine, the worldwide economic impact of COVID-19 would have been $3.4 trillion a year. But even with a COVID-19 vaccine, unequal allocation could cost the global economy up to $1.2 trillion a year in GDP.
25 January 2021
Why healthy food and its local production should be part of the COVID-19 response
COVID-19 is deepening global food insecurity, as the pandemic’s economic impact adds to existing challenges.
24 January 2021
Vaccines that use harmless viruses as a delivery mechanism are vulnerable to being attacked by our immune system – but experimenting with how they are given could get around this.
23 January 2021
Delaying the second COVID vaccine dose – a medical expert answers key questions
A medical professor explains the reasoning behind the delay in the UK and what impact this might have on the vaccine's effectiveness.
22 January 2021
COVAX announces new agreement, plans for first deliveries
COVAX announced the signing of an advance purchase agreement for up to 40 million doses of the Pfizer-BioNTech vaccine; rollout to commence with successful execution of supply agreements.
22 January 2021
Could coronavirus persist in ‘safe havens’ of the body?
Some people continue to shed viral RNA for weeks or months after developing COVID-19. Could persistent pockets of infection be to blame?
22 January 2021
The public health impact of a single-dose HPV vaccination schedule
New review of evidence on a single-dose HPV vaccination schedule is published by PATH-led consortium.
21 January 2021
COVID-19 policy briefs must be realistic: a review by young southern African scientists
African leaders can make strategies to fight COVID-19 more accessible to the people.
21 January 2021
Lasting immunity: Why COVID-19 vaccines may succeed where natural infections fail
Immunity to most coronaviruses is short-lived, but will the same hold true for the virus that causes COVID-19 or vaccines against it?
21 January 2021
What it takes to vaccinate 39 million children in Pakistan
Health workers take COVID-19 precautions to deliver polio drops.
20 January 2021
The Ethics of Prioritizing COVID-19 Vaccination
In the United States and some other countries, members of disadvantaged racial and ethnic minorities have a lower-than-average life expectancy, and therefore are under-represented among those most likely to die from COVID-19. How should…
20 January 2021
5 Reasons to Wear a Mask Even After You’re Vaccinated
Vaccination, face coverings and physical distancing are essential parts of a team effort against the coronavirus.
19 January 2021
Breaking down barriers: UNICEF volunteers lead sanitation survey across Bangladesh
Young volunteers gain new skills and give back to their communities.
19 January 2021
Mutating coronavirus: reaching herd immunity just got harder, but there is still hope
New variants will push the number needed to reach herd immunity up.
18 January 2021
Will the new variant of COVID-19 make re-infection more likely?
New variants of the coronavirus are causing alarm across the UK and South Africa, with many countries closing their borders to travellers from these countries. But what effect could new strains have on our ability to control the pandemic?
18 January 2021
South Sudan: We are ready to take up the challenge
Western Equatoria Ministry of Health and UNICEF are preparing for COVID-19 vaccination campaigns.
18 January 2021
Eureka! Two Vaccines Work — But What About the Also-Rans in the Pharma Arms Race?
How two effective vaccines on the market make it so much harder to quickly test any competing vaccines.
18 January 2021
How COVID-19 is placing increased pressure on water resources for farmers in Cameroon
In Cameroon’s Marua region, the pandemic means farmers are now faced with the double challenge of using what limited water resources they have to grow crops while saving lives through handwashing.
15 January 2021
If I delay getting a COVID-19 vaccine, what impact will it have?
Taking a wait-and-see approach to COVID-19 vaccines could lead to only pockets of the population being protected. Will this be enough to end the pandemic?
15 January 2021
Oxford scientists: how we developed our COVID-19 vaccine in record time
What normally takes decades has been achieved in 12 months, without cutting corners.
15 January 2021
How South Africa is preparing for its COVID-19 vaccine introduction
As participating countries look towards receiving their first batch of COVID-19 vaccines through the COVAX Facility, we examine how South Africa is ramping up its readiness.
15 January 2021
Has Covid-19 permanently altered the development timetable for other vaccines?
Covid-19 has changed the world of vaccines, but that doesn't mean all diseases will get treatments as quickly.
14 January 2021
Preparing ahead: How Imo State harnessed the REDISSE project to improve its COVID-19 response
As at January 12, 2021, Nigeria has had over a hundred thousand confirmed cases of the novel 2019 coronavirus disease (COVID-19) infection. The pandemic has continued to challenge healthcare system...
14 January 2021
As long as humans encroach on nature, pandemics are inevitable — making it important to concentrate resources in areas where people and wildlife are linked.
14 January 2021
Could COVID-19 vaccines be tweaked to cover new coronavirus variants?
We’ve always been able to adapt vaccines to protect against emerging variants and additional pathogen strains, but new vaccine platforms could make this even easier.
14 January 2021
What is it like to receive two doses of a COVID-19 vaccine? One 92-year-old shares his experience.
On 8 January, Derrick C became one of the first people in the UK to receive his second dose of a COVID-19 vaccine, three weeks after the first dose. Here we ask him what that was like.
13 January 2021
How to keep Ebola vaccines at -70°C?
As a Gavi-funded emergency stockpile of Ebola vaccines becomes accessible, we look at the ultra-cold chain equipment used to keep these vaccines at the right temperature.
13 January 2021
Can you spread Covid-19 if you get the vaccine?
Answering this question will take us one step closer to our new normal.
13 January 2021
Why resistance is common in antibiotics, but rare in vaccines
How resistance to drugs originates, and why it's different for vaccines.
13 January 2021
Why lockdown can be bad for your immune system - and what to do about it
Lockdowns are an effective way of reducing COVID-19 infections, but they could take a more general toll on our health if we allow them to.
12 January 2021
COVID-19 immunity: how long does it last?
Long-term protection will depend on the 'memory response' developed by our immune systems – and the initial signs are promising.
12 January 2021
COVID-19 vaccines are set to become the quickest vaccines in history to go from initial trials to rollout, but what lessons can we learn from its speedy predecessor: the Ebola vaccine?
11 January 2021
Lessons from Rwanda’s Fight Against COVID-19
While some of the world's richest and most technologically advanced countries have struggled to contain the spread and morbidity of COVID-19, Rwanda has set a shining example of how to manage a pandemic and safeguard public health. Chief among…
11 January 2021
Why delivering COVID-19 vaccines might be just as hard as developing them
From Liability Laws to Production Delays, the 2009 H1N1 Swine Flu Vaccine Rollout Offers a Cautionary Tale for Today.
8 January 2021
Coronavirus: few vaccines prevent infection – here’s why that’s not a problem
Sterilising immunity means that the immune system is able to completely prevent a virus from replicating in your body. Not all vaccines provide this.
8 January 2021
Trekking through the snow to deliver vaccines
Vaccinators tackle winter conditions and challenging contexts during Afghanistan’s last polio campaign of the year.
8 January 2021
COVID-19 comes as a double blow to those living with HIV
In March 2020, as soon as the first cases of COVID-19 were detected in Kyrgyzstan, a state of emergency was declared, and the country went into lockdown.
7 January 2021
Can Poor Countries Avoid a Vaccine Bidding War?
For all of the good news about the arrival of safe and effective COVID-19 vaccines, the hard truth for the coming year is that global demand will outpace supply. Without a multilateral agreement to allocate doses globally, the road to recovery…
7 January 2021
Is altering the dosing strategy of COVID-19 vaccines a good idea?
Uncertainty in the availability of vaccine doses is prompting some countries to consider altering dosing schedules, or mixing different vaccine types. How could this impact the effectiveness of vaccines?
6 January 2021
COVID-19 FAQs: The 10 questions you need to know the answer to
We believe the best way to address misconceptions is to arm yourself with the facts and have a few key points and statistics. Here’s our list of facts to combat common misinformation.
6 January 2021
Coronavirus vaccines: how will we know when life can go back to normal?
Here's what we still need to find out before we can know when we'll be able to return to our pre-coronavirus ways.
5 January 2021
In less than a year, the world has come together to develop effective COVID-19 vaccines and a multilateral platform for allocating them most efficiently around the world. But with the risk of vaccine nationalism still looming large, now is the…
5 January 2021
What do the new COVID-19 variants mean for vaccine development?
Viruses are constantly mutating and often this process does not have any impact on the risk they pose to humans. However, occasionally mutations can occur which make it easier for viruses to infect us, or which could render vaccines against them…
5 January 2021
Long-lasting symptoms appear unrelated to how bad your infection was, though women appear more affected than men.
4 January 2021
What you need to know about a COVID-19 vaccine
Answers to the most common questions about coronavirus vaccine development.
4 January 2021
Managing Well in the Work-From-Home Era
Managers owe it to their employees to stop treating work from home like a luxury. The office wasn’t invited into the home. It turned up like an unexpected guest – and it shows few signs of leaving soon.
30 December 2020
What are whole virus vaccines and how could they be used against COVID-19?
Whole virus vaccines use a weakened or deactivated version of the disease-causing virus to trigger protective immunity against it.
30 December 2020
Seven vital questions about RNA Covid-19 vaccines
The Pfizer-BioNTech and Moderna Covid-19 vaccines are more than 90% effective, as reported in phase III clinical trials – and the Pfizer-BioNTech vaccine is the first Covid-19 vaccine to be licensed.
29 December 2020
What are viral vector-based vaccines and how could they be used against COVID-19?
Viral vector-based vaccines use a harmless virus to smuggle the instructions for making antigens from the disease-causing virus into cells, triggering protective immunity against it.
29 December 2020
How close are we to a ‘workable’ HIV vaccine?
Despite huge advancements in the treatment and prevention of HIV/AIDS in recent decades, an effective vaccine remains elusive – and is desperately needed to end the global pandemic that kills more than 700,000 people each year.
28 December 2020
Severe COVID may be caused by 'autoantibodies' – here is what that means
Antibodies that go rogue and attack healthy tissue identified in patients with severe COVID.
28 December 2020
What are protein subunit vaccines and how could they be used against COVID-19?
Protein subunit vaccines use fragments of protein from the disease-causing virus to trigger protective immunity against it.
23 December 2020
What are nucleic acid vaccines and how could they be used against COVID-19?
Nucleic acid vaccines use genetic material from a disease-causing virus to trigger protective immunity against it.
23 December 2020
Rethinking healthcare in Africa with geospatial mapping
In August 2020, Nigeria became the last African country to be declared free from wild poliovirus.
22 December 2020
Five mantras for effective COVID-19 vaccine communication
Well-designed communication can increase healthy behaviours, including vaccine uptake. Here are our top five mantras for how to think about COVID-19 vaccine communication.
22 December 2020
MVIP update – 1 million doses administered, Kenya 1st anniversary, cooperation for vaccine access
Kenya marked its 1st anniversary of the launch of the pilot in September, with more than 128,000 children reached with vaccine, and one country health official expressing “a great sense of pride” in being part of the effort to protect children…
22 December 2020
What you need to know about COVID-19 vaccine approvals in Nigeria and South Africa
Before any COVID-19 vaccines can be delivered to the public, their use must be approved by national regulatory authorities. We look into the process before vaccines would be approved for distribution and use in Nigeria and South Africa.
21 December 2020
A united front: building vaccine confidence during a pandemic
To combat vaccine misinformation at home and around the globe, we must build trust.
21 December 2020
What to expect when you get a COVID-19 vaccine
Now that the first COVID-19 vaccine has been approved, and others are on the way, what does getting vaccinated actually involve? Here are some of the logistics involved and what to expect after you’ve had your vaccine.
18 December 2020
There are four types of COVID-19 vaccines: here’s how they work
The fight against COVID-19 has seen vaccine development move at record speed, with more than 170 different vaccines in trials. But how are they different from each other and how will they protect us against the disease?
18 December 2020
Two billion doses of COVID-19 vaccines have been secured to ensure that no-one misses out
The COVAX Facility plans to start rolling out the doses in early 2021 to high-risk groups in participating countries, with the aim of vaccinating up to 20% of populations of participating countries by the end of the year.
18 December 2020
To be effective, COVID-19 vaccination plans must include migrants
As we prepare for one of the world’s largest vaccination efforts, and on the occasion of International Migrants Day, we are coming to a critical reckoning: the need for inclusive approaches in our health-related thinking and practices has never…
18 December 2020
There’s a new strain of COVID-19 – should we worry?
Viruses mutate all the time, but this new mutation affects the viral protein that invades human cells. What does this mean for the pandemic and the vaccine?
17 December 2020
Ask an Expert: Why Are There So Many COVID-19 Vaccines — and Is It Better to Have More?
Vaccines have been approved – so why are we still developing others?
17 December 2020
How did scientists manage to develop safe COVID-19 vaccines in just ten months?
The COVID-19 vaccines currently rolling off production lines have been developed faster than any other vaccine against a new disease in history. How have scientists achieved this incredible feat? And could the lessons learned enable more rapid…
16 December 2020
Why get vaccinated when the flu vaccine doesn’t work well?
The best way we can prevent flu infection is by getting vaccinated. The problem with the flu vaccine is that in some years it doesn’t work as well as others.
16 December 2020
Can I catch COVID-19 from Christmas wrapping paper?
Coronavirus can survive on surfaces, so should unwrapping presents be considered risky? We examine the evidence.
16 December 2020
More typhoid conjugate vaccines, more impact
A second typhoid conjugate vaccine has achieved WHO prequalification and others are in development. More vaccines will help increase access to TCVs.
16 December 2020
2020 Year in Review: The impact of COVID-19 in 12 charts
12 charts provide an overview of our research in the face of a truly unprecedented crisis.
15 December 2020
Will an mRNA vaccine alter my DNA?
Some of the COVID-19 vaccines use messenger RNA to provoke an immune response. But what exactly is this genetic material, and how does it interact with the DNA in our cells?
15 December 2020
A 4-point checklist for assessing countries' vaccine readiness
As the new COVID-19 vaccines begin to ship out, how ready are health systems to manage delivery? Here are four ways countries should frame that question.
15 December 2020
Getting girls on board with the HPV vaccine
New girl-centered toolkit helps health officials develop and implement communications campaigns that resonate with girls in their countries.
14 December 2020
Rallying to vaccinate every child against polio
Community mobilizers inform and prepare communities for vaccinators.
14 December 2020
How to stay safe from COVID-19 this festive period
COVID-19-related restrictions differ from country to country, but as families gather to celebrate during the festive holidays there are some important things you can do to protect yourselves and your loved ones against coronavirus.
11 December 2020
What do immunity passports and vaccination certificates mean for COVID-19 restrictions?
Here’s why continuing to physically distance and wear masks is vital until we can be sure how long vaccine-acquired immunity lasts.
11 December 2020
What psychology can tell us about why some people don’t wear masks – and how to change their minds
Some people respond strongly to perceived threats to their freedom and push back – others are simply more accepting of risk.
10 December 2020
Are African countries ready for the COVID-19 vaccine?
Preparing African countries for COVID-19 vaccines will require thoughtful planning and unprecedented coordination across a wide-range of stakeholders.
10 December 2020
We need more data on the low-dose, high-dose regimen used in one arm of the trial, which may make the vaccine more effective.
9 December 2020
Mobile phone data reveals the most effective strategies for reducing COVID spread
Restaurants, gyms and religious establishments appear to account for most coronavirus infections in US cities, but new analysis suggests there are strategies which can reduce the risks.
8 December 2020
Could Ebola survivors hold the key to understanding long COVID?
Like patients with long COVID, some Ebola survivors have lingering symptoms which can make it difficult to work or function in everyday life. Dr Janet Scott has been studying these survivors, and now also has her sights on COVID-19. She tells us…
8 December 2020
What if I’ve already had COVID – do I still need a vaccine?
7 December 2020
Routine vaccinations during a pandemic – benefit or risk?
Some countries may stop their vaccination programs for a while to reduce the risk of spreading COVID-19. But which is better: fewer coronavirus infections or making sure children get all their usual vaccinations?
7 December 2020
Without a greater focus on the gender dynamics of the COVID-19 crisis, women and girls will suffer long-term handicaps that constrain their economic prospects for years to come, if not permanently. We already know enough about the pandemic's…
4 December 2020
Keeping trust in immunisation during the COVID-19 pandemic
At this crucial moment for immunisation, considering community perceptions of vaccination has never been more important.
4 December 2020
Health workers use special days to reach every child with life-saving vaccines
Not even the COVID-19 pandemic will stop them.
3 December 2020
“Don’t use COVID-19 as an excuse not to immunize your children, you will regret it.”
Janet, mother of twins, tells fellow mothers.
2 December 2020
Five ways that scientists are ensuring the safety of COVID-19 vaccines
As companies race to develop COVID-19 vaccines, some development processes have been run in parallel to stop the pandemic as quickly as possible. Yet safety remains paramount; now that we are on the brink of rolling out some of the vaccines that…
1 December 2020
How small clinical trial sample sizes can offer important findings
Scientists have been racing to develop COVID-19 vaccines that could reach millions, yet many of the studies have surprisingly small sample sizes drawn from the clinical trials. Does that matter?
1 December 2020
Why an antidepressant could be used to treat COVID-19
Fluvoxamine has shown positive results in early trials.
1 December 2020
The peril of ignoring childhood pneumonia in the age of COVID-19
The COVID-19 pandemic now threatens global progress on preventing and treating childhood pneumonia, potentially reversing decades of health gains for the world’s most vulnerable children.
30 November 2020
COVID-19 could undermine progress towards reducing infant mortality
Over the past three decades, improvements to maternal and newborn health have led to many more infants surviving beyond the first 28 days of life. But disruptions to health services caused by the COVID-19 pandemic may now be undoing years of hard…
27 November 2020
Four reasons why we need multiple vaccines for Covid-19
Having a range of Covid-19 vaccines available for people to use around the world will be essential to bringing the pandemic under control. Here’s why.
27 November 2020
10 things you should know about vaccine candidates
Despite the benefit of all the recommended public health measures in preventing transmission, vaccines still provide us with the best chance of our lives returning to some semblance of normality.
26 November 2020
Equal, rapid access to COVID-19 vaccines won’t just save lives; it will save money
Research suggests that the quickest way to end the pandemic and limit the economic damage is for all countries to benefit from a coordinated global vaccine deal.
25 November 2020
IOM and Gavi working together to give the most vulnerable ‘a good start’ in South Sudan
This week Gavi signed a historic agreement with the International Organization for Migration (IOM) to improve immunisation coverage for migrants and forcibly displaced persons around the world. IOM’s South Sudan Communications Officer, Liatile…
25 November 2020
Ensuring safety of COVID-19 vaccines
CEPI spoke with vaccine safety expert, Dr Robert Chen, Science Director of The Brighton Collaboration – the largest global organisation of scientific experts on vaccine safety – about how vaccine safety is assessed in clinical trials and how…
25 November 2020
Anxiety, depression and insomnia: the impact of COVID-19 on mental health
COVID-19 patients are at an increased risk of being diagnosed with anxiety, depression or insomnia. Here’s a closer look at how the SARS-CoV-2 virus can impact your mental health.
24 November 2020
Why the Oxford AstraZeneca vaccine is now a global game changer
The global pandemic is far from over, but this latest in a series of welcome announcements brings renewed hope even if several hurdles remain.
24 November 2020
Gavi and IOM join forces to improve immunisation coverage for migrants
Memorandum of understanding signed today will strengthen collaboration on vaccination efforts and related health services for migrants and forcibly displaced persons across the world
24 November 2020
The longest mile in the COVID-19 vaccine cold chain
Promises of COVID-19 vaccine doses for developing countries will face challenges along the crucial cold chain.
23 November 2020
COVID-19 ‘Vaccine for the World’ shows up to 90% efficacy
Interim analysis of the AstraZeneca/Oxford COVID-19 vaccine candidate – to which Gavi has secured access – suggests an efficacy of 62– 90%. Crucially, the vaccine can be administered and distributed using existing health care and supply chain…
23 November 2020
Oxford vaccine results are in: here's how to ensure it is used
The Oxford vaccine – developed in partnership with AstraZeneca – stops 70% of people developing COVID symptoms, and, depending on how the doses are given, may even protect up to 90% of people.
23 November 2020
Resumed immunization campaigns are critical to preventing COVID-19 as well as polio
Local adaptation and innovation has allowed the resumption of polio immunization campaigns – and points the way to more effective, community-based delivery of a whole range of basic health services.
23 November 2020
COVID-19 antibody levels could fall faster in men than women
New research suggesting that antibodies reduce faster in men compared with women could have implications for vaccine development.
20 November 2020
Although antimicrobial resistance has been a known and growing problem for decades, only one new class of antibiotics has been discovered since 1984. Tackling AMR requires a fundamental change in how new antibiotics are valued, and government…
20 November 2020
Natural immunity to COVID-19 may be long-lasting
Until now, we didn’t know how long immunity after infection with COVID-19 would last – new research suggests it could be long-lasting.
20 November 2020
Coronavirus vaccine results are pouring in, and it's good news for older people
Early results from COVID-19 vaccine trials are starting to emerge, and scientists have received the first reports from three independent studies with optimism because protection against the coronavirus is possible.
19 November 2020
What is lateral flow testing and how could it be deployed against coronavirus?
Unlike PCR tests, which involve complex laboratory equipment and highly trained staff, lateral flow tests can be processed on the spot and return a result far quicker. But how exactly do they work, and could they really make a difference to the…
19 November 2020
Rediscovering the public health origins of WASH
As COVID-19 continues to surge over the globe, it forces us to reckon with the fact that true global health equity – universal access to primary healthcare – is an unfinished task that we pay for at our collective expense. Water, sanitation, and…
18 November 2020
Moderna follows Pfizer with exciting vaccine news – how to read these dramatic developments
It is very exciting to hear another positive story about vaccine trial results – a good vaccine is the most likely way of ending the pandemic.
18 November 2020
What is the difference between efficacy and effectiveness?
The two terms used to describe how well a drug or vaccine works are often used interchangeably, but they are not actually the same thing – here’s why.
17 November 2020
The Human Cost of COVID-19: Eugene
Vienna, Austria – In this final story in the World Health Organization series exploring the human cost of the COVID-19 pandemic, Eugene, a care-home nurse in Austria, shares the story of how he survived coronavirus.
17 November 2020
Volunteers take lead on contact tracing in hard-to-reach communities
As COVID-19 has overwhelmed the medical system, a group of volunteers in Nigeria is undertaking the task of slowing the disease’s spread within communities.
17 November 2020
Vaccine roll-out is still months away – how can we avoid more lockdowns in the meantime?
The main way the virus is thought to spread is through respiratory droplets and fomites (contaminated objects or materials such as clothes, furniture and door handles). With this mode of spread, most infections take place through close contact,…
16 November 2020
Video: How Kenya is prioritising routine immunisation services during the COVID-19 pandemic
The Ministry of Health and UNICEF Kenya, with support from Gavi, are working to ensure that routine health services, such as immunisation, continue during the pandemic. Watch their video to learn more.
16 November 2020
5 ways COVID-19 is exacerbating global poverty
COVID-19 has presented many new social and economic challenges, and is exacerbating already existing ones. One such challenge is global poverty. Right now over 700 million people live in extreme poverty worldwide, which is defined as living on…
16 November 2020
The Human Cost of COVID-19: Gracia
In this third story in the World Health Organization series exploring the human cost of the COVID-19 pandemic, Gracia, a junior high school student in West Papua, learns life skills for the future.
13 November 2020
COVAX Facility governance explained
How will the COVAX Facility ensure equitable access to COVID-19 vaccines is indeed equitable? By Aurélia Nguyen, Managing Director, Office of the COVAX Facility
13 November 2020
COVAX Facility convenes first meeting of COVAX AMC engagement group
The COVAX AMC Engagement Group, composed of Gavi COVAX AMC participants, donors, and other stakeholders, forms a key component of Facility governance.
13 November 2020
'Back to normal by spring': are we expecting too much from the first COVID-19 vaccines?
Pfizer’s update certainly is fantastic news. A COVID-19 vaccine could well be approved and ready for use in the next few months. But whether that means we can all get back to normal life by early 2021 is less certain.
13 November 2020
The Human Cost of COVID-19: Shukria
In this second story in the World Health Organization series exploring the human cost of the COVID-19 pandemic, Shukria, a volunteer, talks about how she helps her community with providing masks and awareness messages about COVID-19.
13 November 2020
The European Commission, France, Spain, The Republic of Korea and the Bill & Melinda Gates Foundation pledge US$ 360 million to Gavi’s COVID-19 Vaccines Advance Market Commitment (COVAX AMC)
12 November 2020
A smart label on vaccine vials will be vital for safely rolling out future COVID-19 vaccines
Interim results suggesting that Pfizer/BioNTech’s COVID-19 vaccine provides more than a 90% efficacy, offers hope that immunisation can be effective against COVID-19. But the need to store this vaccine at “ultra cold” temperatures could pose…
12 November 2020
Until a coronavirus vaccine is ready, pneumonia vaccines may reduce deaths from COVID-19
The yearly influenza season threatens to make the COVID-19 pandemic doubly deadly, but I believe that this isn’t inevitable.
12 November 2020
The Human Cost of COVID-19: Nombasa
In the first of a World Health Organization series exploring the human cost of the COVID-19 pandemic, Nombasa, a frontline healthworker, makes an urgent appeal to governments and global health partners.
11 November 2020
Six in ten children are immune to the COVID-19 virus despite never being infected by it
Immunity triggered by exposure to the coronaviruses that cause the common cold could protect people, especially children, against the SARS-CoV-2 virus.
11 November 2020
Adverse events following immunisation: what are they, and when are they cause for concern?
A successful vaccine produces the best possible immune response, whilst keeping side effects to a minimum. When adverse events following immunisation (AEFIs) do occur, it is important that they are reported, especially if they are serious, even…
10 November 2020
Pfizer’s COVID-19 vaccine may be over 90% efficacious, so what happens next?
An interim analysis of the Pfizer/BioNTech vaccine candidate suggests is more efficacious than many had dared to expect. The announcement is a welcome indication that a safe and effective COVID-19 vaccine might be within reach, but there are…
10 November 2020
Why we will always need vaccinations
Vaccination programmes have prevented millions of deaths worldwide, but their continued success relies on our continued participation.
9 November 2020
Do mutations of COVID-19 virus in mink pose a threat to people?
With Denmark culling its entire farmed mink population following discovery of a mutated form of SARS-CoV2, are we at risk of further complications and diseases from animal-human transmission?
9 November 2020
Coronavirus: believing in conspiracies goes hand in hand with vaccine hesitancy
While developing an effective vaccine probably won’t bring an immediate end to the pandemic, it’s clear that things can’t begin to return to normal without one. Anything that reduces a future vaccine’s effectiveness will be a problem. This…
9 November 2020
Come together: how the fight to end polio can help the COVID-19 recovery
The world is anxiously awaiting the development of a safe and effective COVID-19 vaccine. Nearly 60 years ago, the world was also waiting in eager anticipation of a publicly available vaccine to stop a disease that was ravaging communities around…
6 November 2020
Why understanding superspreaders could be one key way of controlling the COVID-19 pandemic
Superspreading events, where one person infects tens of others, appear to be playing an increasingly significant role in the spread of COVID-19. So what have we learned about these events and how can we stop them from fuelling the pandemic?
6 November 2020
Gavi COVAX AMC: a shot in the arm for international cooperation
Never has the development of vaccines been so widely anticipated as for COVID-19, and arguably never has so much been at stake. Because without COVID-19 vaccines, we cannot bring this crisis to a swift end.
5 November 2020
How does COVID-19 trigger a loss of smell and other olfactory disorders?
Anosmia is the medical term for a sudden loss of smell and has been associated with COVID-19. Here’s a closer look at the olfactory dysfunctions linked to the SARS-CoV-2 virus.
5 November 2020
How deliberately infecting volunteers with COVID-19 could help accelerate vaccine development
Josh Morrison, Co-founder and Executive Director of 1Day Sooner, an organisation that advocates on behalf of challenge trial volunteers, explains why.
4 November 2020
Equitable COVID-19 vaccine distribution will lead to the biggest reduction in deaths
Mathematical modelling suggests that if wealthy countries stockpile COVID-19 vaccines, we will see nearly twice as many deaths than if vaccines were shared equally across the globe.
3 November 2020
COVAX Facility convenes first meeting of COVAX Shareholders Council
The COVAX Shareholders Council, composed of all self-financing participants, forms a key component of Facility governance.
2 November 2020
We need Covid-19 treatments as well as vaccines – and they have to work for everyone
Effective treatments that are accessible to everyone who needs them have to be part of the solution to the coronavirus pandemic – here's why.
2 November 2020
What impact does malnutrition have on the effectiveness of vaccination?
Malnutrition can affect the immune system and the quality of immune response to vaccinations, with potential implications for low-income countries where COVID-19 is already fuelling a "hunger pandemic" in the most vulnerable people.
30 October 2020
COVAX welcomes appointment of civil society representatives
As part of the global response to the COVID-19 pandemic, COVAX – the vaccines pillar of the Access to COVID-19 Tools (ACT) Accelerator, co-led by Gavi, CEPI, and the WHO – welcomes the appointment of civil society organisation representatives to…
30 October 2020
Overcoming the COVID-19 Disruption to Essential Health Services
It is clear that COVID-19 will persist much longer than anticipated. If countries do not take action soon to ensure the continuity of essential health services during the pandemic, the future death toll from communicable and noncommunicable…
30 October 2020
How COVID-19 may have increased dengue infections in Thailand and Singapore
Spending less time in the workplace usually results in lower rates of infectious disease, but workplace closures in Southeast Asia and the Western Pacific may be increasing exposure to the mosquitoes that transmit dengue virus.
29 October 2020
How geospatial technology can help to zero in on zero-dose children
Combining geographical information on populations, locations of health care sites, and the movement of vaccinators can offer insights into how efficient and equitable vaccination coverage is, and has great potential to improve immunisation…
29 October 2020
Digitizing vaccine cold chain, key to post-pandemic immunization in Indonesia
For some vaccinators in the vast archipelagic nation of Indonesia, a day in their professional life may involve trekking through deep tropical valleys and jungles or crossing the open waters on rickety boats to isolated islands.
27 October 2020
Why protecting, promoting essential services for women and children is now more critical than ever
Now, COVID-19 is unleashing substantial health, social and economic impacts in every corner of the globe. But it is the poorest countries and the most vulnerable communities around the world that stand to suffer the most from this protracted…
26 October 2020
CEPI’s strategic investments in vaccine manufacturing at facilities around the world will support the COVAX goal to produce 2 billion doses of safe and effective vaccine by the end of 2021.
26 October 2020
Let’s flatten the infodemic curve
We are all being exposed to a huge amount of COVID-19 information on a daily basis, and not all of it is reliable. Here are some tips for telling the difference and stopping the spread of misinformation.
23 October 2020
Ghana launches polio campaigns despite the challenges of COVID-19
In the face of the challenges posed by the pandemic, Ghana is working to protect 4.5 million at-risk children from polio through the launch of two polio vaccination campaigns. Here’s a closer look at those efforts for World Polio Day.
22 October 2020
The COVID-19 pandemic has shone a spotlight on social, economic, and environmental risks that have been building for the past half-century of neoliberalism. Even amid the deep uncertainties of today's global situation, one thing is clear: it is…
22 October 2020
We need a global response to the COVID-19 pandemic
President of Niger H.E. Issoufou Mahamadou talks about the importance of routine immunisation and Gavi support in Niger, and the need for ensuring universal access to COVID-19 vaccines through the COVAX Facility.
21 October 2020
How Gavi, UNICEF and WHO supported Timor-Leste’s successful COVID-19 response strategy
Timor Leste has kept COVID-19 infections to a minimum, and thanks to effective collaboration has managed to successfully reverse the initial declines seen in immunisation coverage and health service delivery.
21 October 2020
Timor-Leste’s Director-General of Health Services for the Ministry of Health discusses the unique challenges of tackling COVID-19 in Timor-Leste and how have they been addressed.
20 October 2020
Why we need a “portfolio approach” to COVID-19 vaccine development
Most vaccine candidates in early development fail: this is the stark reality of vaccine development.
20 October 2020
Children who get zero vaccines deserve 100% of our attention
Over 50% more children were immunised in Gavi countries in 2019 than in 2000, yet 10.6 million children continue to miss out entirely on basic vaccinations. Here’s why reaching these children and setting them on the pathway to full immunisation…
19 October 2020
Once we have effective Covid-19 treatments, it shouldn’t only be the rich who benefit
We need a range of treatments to make Covid-19 preventable and treatable. Jeremy Farrar describes recent progress made by research and why more investment is needed.
16 October 2020
Brazil city ‘might have reached herd immunity'
Herd immunity threshold may have been reached in Amazonas capital, Manaus, but experts warn that herd immunity is not the end of the pandemic.
16 October 2020
Why some people might be immune to certain COVID-19 vaccines
Vaccines based on the common cold virus are at the forefront of the COVID-19 vaccine race, but they may be less effective in people who have previously been infected by these common pathogens. So how could we overcome this challenge?
15 October 2020
Why handwashing with soap is the most effective way to stop viruses
Global Handwashing Day and the ongoing spread of COVID-19 is a timely reminder about the importance of handwashing with soap as an effective and affordable way to stay healthy.
15 October 2020
COVID-19 as an awakening for hand hygiene access
Globally 3 billion people lack hand hygiene facilities at home and two out of five health care facilities lack hand hygiene at points of care. As the pandemic unfolded around the world, hand sanitizer and handwashing stations became as in-demand…
15 October 2020
Taking the long view on vaccine markets
Gavi’s long-term approach to developing healthy markets for critical vaccines has led to greater stability and security, providing countries with the confidence that supplies will be available to meet their demand.
14 October 2020
2019 was a landmark year for countries co-financing their vaccine programmes
In 2019, a higher share of Gavi-supported countries than ever before met their co-financing obligations on time, thanks to strong political commitment.
14 October 2020
How “data poverty” could worsen health inequalities during the pandemic and beyond
Big data has the potential to change society for the better, but this opportunity is being undermined by a failure to collect data from across societies and make it publicly available.
13 October 2020
Strong systems for strong vaccine coverage
In 2019, countries delivered more than 230 million routine vaccinations, a record number, supported by unprecedented levels of health system funding from Gavi to support immunisation and protect the most vulnerable children. Here is what Gavi did…
12 October 2020
What is the world like for girls today?
On International Day of the Girl Child, Gavi’s Megan Holloway looks at how COVID-19 is impacting the lives of girls.
12 October 2020
A Moment of Truth in the Pandemic
As the most ambitious pandemic-response initiative ever conceived, the COVID-19 Vaccine Global Access Facility is the best chance the world has to bring the pandemic to an end. But to succeed, COVAX requires broad international buy-in, based on…
9 October 2020
The World Food Programme wins 2020 Nobel Peace Prize amidst ‘hunger pandemic’ triggered by COVID-19
These global efforts are increasingly urgent as the economic impact of the COVID-19 pandemic continues to put millions of lives at risk from famine and malnutrition.
9 October 2020
Will silent reinfections drive the spread of COVID?
People who have had COVID-19 can develop an immune response that normally protects people from recurrent infection. But now that reinfections of COVID-19 have been recorded, what does that mean for our ability to fight the virus?
9 October 2020
Immunization continues amid COVID-19
European Commission Civil Protection and Humanitarian Aid Operations (ECHO) humanitarian air bridge made it possible.
8 October 2020
Japan pledges US$ 130 million to support global access to COVID-19 vaccines
Japanese Government pledges US$ 130 million in funding to the Gavi COVAX Advance Market Commitment (AMC), bringing the total raised to roughly US$ 1.8 billion.
8 October 2020
Protecting community health workers means protecting communities in the DRC
Preventing and controlling infectious disease is possible with dedication of health workers, multi-stakeholder collaboration and equitable access to vaccines. Africa’s wild polio-free certification, which took decades of collaborative effort, is…
7 October 2020
What are monoclonal antibodies – and can they treat Covid-19?
For more than 30 years, monoclonal antibodies have transformed the way we treat many diseases. Researchers think they are also one of the most promising treatments for Covid-19. Here's why.
7 October 2020
How emergency use authorisations could accelerate access to COVID-19 vaccines
Emergency use procedures are designed to make potentially life-saving medical products available as quickly as possible during health emergencies. A record number have been granted since the arrival of COVID-19 pandemic, but what does this mean…
6 October 2020
AVADAR: How digital health fast-tracked Nigeria’s drive to eradicate polio
Polio, a contagious disease caused by the poliomyelitis virus is transmitted primarily when stool from someone infected contaminates foods, drinks or water sources. It invades the nervous system and could, in a matter of hours, lead to complete…
6 October 2020
Why I volunteered for a COVID-19 vaccine trial
Vaccines are designed to trigger an immune response to pathogens we’ve never encountered before. But how does it feel to be one of the first humans to encounter a new vaccine? British communications consultant Heather Macdonald-Tait explains what…
6 October 2020
Countries pledge nearly US$ 1 billion to support equitable access to COVID-19 vaccines
The United Kingdom, Canada, Germany, Italy and Sweden pledge approximately US$ 960 million to Gavi’s COVID-19 Vaccines Advance Market Commitment (COVAX AMC)
5 October 2020
How COVID-19 is heightening the economic risks in Gavi-supported countries
In a matter of months, the COVID-19 pandemic has devastated the global economy. Now a new study looks at how this economic shock is impacting sovereign debt levels of Gavi-supported countries.
5 October 2020
Q&A with Professor Salim Karim
Africa has not been as hard hit by the COVID-19 pandemic as predicted. Here, we talk to Professor Salim Abdool Karim, the head of South Africa's Ministerial Advisory Committee on COVID-19 to find out why and what the future might hold.
2 October 2020
Understanding urban challenges in Uganda
In the first of this series, we look at the highlights of an evaluation to determine the potential barriers to immunisation caused by the increase in urbanisation.
2 October 2020
Why the world is at risk without immunisation
Vaccines save lives by protecting children and adults from diseases. COVID-19 pandemic is a clear example of what a world without vaccines could look like. Governments should ensure that delivery of essential services such as vaccines remains a…
2 October 2020
How good quality data is vital to saving lives
Throughout the 2016–2020 strategic period, the Vaccine Alliance has worked with countries to improve data quality. From GIS to SMS, new tech and tools aim to reach more people with life-saving immunisation.
1 October 2020
How Gavi’s co-financing model works
To bring countries on a trajectory towards financial sustainability, and to empower them to take ownership
of their vaccination programmes, Gavi has pioneered an approach to co-financing and transition.
1 October 2020
The Gavi Board has approved the provision of US$ 150 million in initial funding to jumpstart support COVAX AMC-eligible countries’ readiness to deliver COVID-19 vaccines, in the form of planning, technical assistance and cold chain equipment
1 October 2020
A Nurse in Uganda is a Trusted Messenger of Hope
Her own healthy baby son is how Ugandan nurse Maureen Wandawa demonstrates the benefits of immunization. Working together to build confidence in, and access to, vaccines for all who need them is one way we can #UniteforHealth to keep us all safer…
30 September 2020
Download for life: a mobile app to improve vaccine coverage in Côte d’Ivoire
Gavi's partnership with telecoms provider Orange and the Ministry of Health overcomes barriers to childhood immunisation through tailored, tested technology.
30 September 2020
From equality to global poverty: how Covid-19 is affecting societies and economies
The Covid-19 pandemic is a social and an economic crisis just as much as it is a health crisis – its repercussions, severe and far-reaching, are being felt across the world.
30 September 2020
More than one million people have died of COVID-19
The true number could be much higher, and two million could die before we get a vaccine, says the World Health Organization.
30 September 2020
How do vaccine challenge trials ensure the benefits outweigh the risks?
The UK is expected to host the world’s first COVID-19 human “challenge” trials, which will involve deliberately infecting healthy volunteers with coronavirus to assess the effectiveness of experimental vaccines. So far, around 2,000 potential…
30 September 2020
Recovering Better through Gender Equity
Gender equality must be at the heart of not only our response, but our attempts to restructure systems to be fairer and more equal to recover better.
29 September 2020
Global investors must support pharma solidarity and collaboration in the response to COVID-19
The prospect of having the first supplies of at least a few effective COVID-19 medicines and vaccines by the end of 2020 is a key driver of recent market optimism.
29 September 2020
The benefits of immunisation extend beyond preventing childhood deaths. Vaccines are also a vital tool in the fights against cancer, outbreaks and antimicrobial resistance.
29 September 2020
What does COVID-19 mean for this year’s flu season?
Every winter, hundreds of thousands become infected with seasonal influenza, which kills between 290,000 and 650,000 people worldwide each year. But this year, we have another respiratory illness to contend with: COVID-19. So, what does this mean…
29 September 2020
Collaboration among the Serum Institute of India (SII), Gavi, the Vaccine Alliance and the Bill & Melinda Gates Foundation will accelerate manufacturing and delivery of up to an additional 100 million doses of future vaccines, if proven to be…
29 September 2020
The world needs Gavi now more than ever
When I join Gavi in January, it will be at a time when it is contemplating the most ambitious period in its history.
28 September 2020
The last mile of polio eradication and the vaccination challenges it brings
We are close to a polio-free world, yet cases of vaccine-derived disease are challenging the eradication effort.
28 September 2020
Classroom precautions during COVID-19
Tips for teachers to protect themselves and their students.
28 September 2020
The goal of our market shaping work is to help ensure vaccine markets work better for lower-income countries. We want the maximum number of people to receive the life-saving and health-protecting benefits of immunisation.
25 September 2020
Experimental approaches to address post-transition risks
After transitioning out of Gavi support in 2017, the Republic of Moldova is mobilising champions and advocates to strengthen vaccine confidence – which is crucial to the success and sustainability of immunisation programmes.
25 September 2020
A secret ingredient for stronger vaccines?
An ingredient called dmLT could be the key to improving vaccine effectiveness in low-resource settings.
24 September 2020
Keep focus on emerging infections, Disease X: analysts
Biggest funders of emerging infectious diseases R&D are also biggest recipients. Ebola and Zika experienced R&D spike in wake of epidemics. US is losing global leadership role in the field.
24 September 2020
How to keep vaccine production going during a pandemic?
Vaccine manufacturers have worked hard to adapt to a new normal of keeping supplies for immunisation programmes going in the midst of the COVID-19 pandemic.
24 September 2020
Typhoid: immunising against antimicrobial resistance
Typhoid fever is increasingly resistant to the main antibiotics used to treat it. Gavi is supporting a new vaccine to help control this deadly disease – and fight antimicrobial resistance.
24 September 2020
Gavi’s commitment to diversity, equality and inclusion
We commit to fostering a just, equitable and diverse culture free from racism and discrimination in which all staff, partners and stakeholders feel empowered, safe and heard.
24 September 2020
Which COVID-19 test is most relevant to me?
At the beginning of the pandemic there was a mad scramble to develop a test which would accurately diagnose COVID-19 infection. Now, six months in, hundreds of testsare available – but how do they differ, and which test is the most appropriate…
23 September 2020
Gavi at UNGA: Global solidarity to defeat COVID-19 and create a better world for all
September 2020 marks the 75th anniversary of the United Nations General Assembly (UNGA). This year, the focus of the high-level General Debate is the importance of effective multilateralism.
23 September 2020
What does the pausing of the AstraZeneca trial mean for other COVID-19 vaccines?
Gavi’s Derrick Sim, Director of Vaccine Supply and Demand, discusses why it is sometimes important to halt clinical trials.
23 September 2020
Leaders in the fight against infectious diseases
Snapshots from DRC, India and Zambia illustrate country ownership and progress in the fights against Ebola, polio and HPV.
23 September 2020
10 reasons why pandemic fatigue could threaten global health in 2021
Being in a constant state of high alert and uncertainty is exhausting yet health officials warn that we can’t let our guard down yet and resisting living with the ‘new normal’ could threaten our health.
23 September 2020
Coronavirus vaccine: why it’s important to know what’s in the placebo
Some researchers conducting clinical trials on a COVID-19 vaccine have not revealed to the public what the placebo contains, but they should.
22 September 2020
How health systems work and why they matter
Supporting health systems is essential for Gavi’s work to improve immunisation coverage and equity.
22 September 2020
Could COVID-19 be fuelling drug resistance?
We need to understand the impact of Covid-19 on wider health issues to shape better public health responses and limit long-term consequences. Drug resistance is one of these, Gemma Buckland-Merrett explains.
22 September 2020
How can we make fair and equitable access to COVID-19 vaccines a reality?
How will COVAX ensure that COVID-19 vaccine doses reach all countries at the same time, and protect those people that need it the most?
21 September 2020
Resilience and the risks to global health security
When disaster strikes a country, the impact on people’s health can be immense and long-lasting. As the effects of climate change are felt around the world through rising temperatures and sea levels, natural disasters are increasingly frequent and…
21 September 2020
When I was 12, I received the HPV vaccine just like most girls my age in Rwanda. The day after we got the first dose, my classmates started spreading rumours about the vaccine that they had heard from their families and communities.
18 September 2020
Vaccines are the best tools yet invented to prevent child deaths and protect people’s health. Gavi funding for access to vaccines has protected a generation of children growing up in lower-income countries. Gavi funds twin approaches to…
18 September 2020
There’s more than one way for a COVID-19 vaccine to end this pandemic
Effective vaccines prevent individuals from developing disease, but some also stop people transmitting the pathogens that cause them. What role will they have to play in ending the COVID-19 pandemic?
18 September 2020
The three Vs needed to end this pandemic
While scientific and vaccine manufacturing community make huge strides in the race towards that goal, it is important to remember that vaccines are only one of three Vs needed to beat this coronavirus.
17 September 2020
The role of social mobilisers during COVID-19
How one social mobiliser in South Sudan has managed to contribute to health security in her region.
17 September 2020
Our shared future is not a choice
2020 was already going to be a monumental year — the beginning of the 10-year countdown for achieving the Sustainable Development Goals (SDGs).
16 September 2020
Mapping vaccine confidence worldwide
Anecdotes of how people feel about vaccines are plenty, but there have been few attempts to gather robust global data. This five-year study reviewed survey responses from over a quarter of a million people around the world on how they felt about…
16 September 2020
A record-breaking year for childhood immunisation
Gavi’s CEO provides an overview of its flagship publication, launched today.
15 September 2020
Malawi: Reaching girls earlier
In Malawi, primary school drop-out rates are among the highest in Africa. To try and guarantee high coverage, the HPV vaccine is administered to 9-years-old girls.
14 September 2020
Why is no one safe until everyone is safe during a pandemic?
No one is safe until everyone is safe. This phrase has become a slogan for global health figures but what does it mean in the worldwide COVID-19 response?
14 September 2020
COVID-19 vaccines: what happens after clinical trials
If a COVID-19 vaccine is to reach the global public sometime next year, it will be the result of one of the fastest developments and rollouts of a vaccine against a new disease ever. In contrast, the RTS,S malaria vaccine, which is currently…
14 September 2020
How Ethiopia is maintaining health services during a pandemic?
Ethiopia has overtaken Nigeria to become the Gavi-eligible African country most affected by COVID-19. Over the past week, the number of confirmed cases in Ethiopia has grown exponentially. Despite the pandemic, immunisation activities – both…
14 September 2020
COVID vaccine is being speeded up but urgency cannot be at expense of safety, says Dr Seth Berkley
As CEO of Gavi, the Vaccine Alliance funded largely by Bill Gates, Dr Seth Berkley has helped vaccinate almost half the world’s children from fatal and debilitating diseases. His current baby is the COVAX Facility to help develop, manufacture and…
11 September 2020
Are vaccines a global public good?
As COVID-19 vaccines have a critical role to play in ending this pandemic crisis, many experts have described them as a global public good. But what exactly does that mean?
11 September 2020
Supply chains: The lifeline for getting PPE to community health workers
You may have heard the saying, “no products, no programs,” but for those who work in public health during COVID-19, the saying has become “no PPE, no programs.” And for community health workers (CHWs) who play a vital role in providing health…
9 September 2020
How vaccination can reduce sepsis and save millions of lives
Many of the infections that can lead to sepsis are becoming resistant to antibiotics, which means that preventing them by vaccination is critical.
7 September 2020
Ethiopia Reaching girls at scale
Helping rural and urban girls across Ethiopia understand cervical cancer and HPV.
4 September 2020
Different types of immunity and why they matter to COVID-19
Antibodies are one route to immunity against disease, but T cells and innate immunity also play a crucial role in protecting us. So, how could these different types of immunity be mobilised against COVID-19
4 September 2020
How Somalia is resuming vaccination campaigns despite COVID-19
More than 3,000 health workers are conducting a three-day health campaign from 30 August to 1 September 2020 to ensure that around 400,000 children aged under five receive measles and polio vaccines, as well as vitamin A and deworming tablets, at…
3 September 2020
To end this global health crisis we don’t just need COVID-19 vaccines, we also need to ensure that everyone in the world has access to them.
2 September 2020
Who should we vaccinate first?
When COVID-19 vaccines become available demand is likely to outstrip supply, at least initially. So, who should be first in line?
1 September 2020
Modelling the Manufacturing Process for COVID-19 Vaccines: Our Approach
Researchers across the world are working flat out to develop and manufacture a vaccine for COVID-19 that can end what has been the worst pandemic in at least a century.
31 August 2020
How to measure the success of a COVID-19 vaccine?
Dr Melanie Saville, CEPI’s Director of Vaccine Development, discusses what a successful vaccine against COVID-19 would involve, some of the unknowns and the challenges that vaccine developers are wrestling with, and what makes CEPI’s approach…
28 August 2020
Before the pandemic began, the Democratic Republic of the Congo (DRC) was already facing a severe measles outbreak which started at the end of 2018. Despite huge challenges caused by COVID-19 and other diseases, the largest measles outbreak in…
28 August 2020
How the African Region is Celebrating the End of Wild Polio while cVDPV Outbreaks Continue
28 August 2020
Is it possible to get COVID-19 more than once?
What do the first confirmed cases of reinfection with COVID-19 mean for the rest of us and future of this pandemic?
28 August 2020
Australia commits AU$ 80 million to guarantee access to COVID-19 vaccines for all
The funding will support the Gavi COVAX Advance Market Commitment (AMC), which aims to secure doses of COVID-19 vaccines for 92 low- and middle-income countries and economies at the same time as wealthier nations
27 August 2020
DRC: The great lengths that polio vaccinators go to reach every last child
By foot, boat and bicycle, thousands of volunteer vaccinators in the Democratic Republic of Congo (DRC) go to extraordinary efforts, sometimes at personal risk, to help eradicate polio.
27 August 2020
An estimated $15.9 trillion has been mobilised to respond to the health and economic impact of the COVID-19 pandemic. Some of this has gone to multilateral and bilateral funders to support low- and middle-income countries’ (LMIC) governments.
26 August 2020
Borno: Africa’s Last Wild Poliovirus Frontier
When Aisha took her son Busami Modu to his grandmother’s house in Kuya, a village in Borno state, Nigeria, she waved goodbye to a healthy, happy little boy. A “beauty to behold,” she recalls. The next time she saw him, he was paralysed and unable…
24 August 2020
Can vaccine clinical trials be sped up safely for COVID-19?
One of the most time-consuming parts of vaccine research and development is the testing of a vaccine. How does this work, and how, in the context of COVID-19, are scientists trying to speed it up?
21 August 2020
Data from global Ipsos survey shows 37% of those polled worldwide think it is likely a vaccine will be available by the end of the year. But is this optimism misplaced?
19 August 2020
CSOs will play a vital role in the development and implementation of the COVAX initiative as well as the deployment of any successful vaccine through COVAX.
14 August 2020
How is Nigeria addressing the public health challenges due to COVID-19?
As one of the African countries most affected by COVID-19, Nigeria has faced significant economic and health impacts, including to routine immunisation, in the face of the pandemic.
14 August 2020
What do diarrheal disease and COVID-19 have in common?
Diarrheal disease is the second leading infectious killer of children under five worldwide. Lessons learned from tackling this deadly disease could also help us recover from COVID-19 stronger than ever.
13 August 2020
Somalia responds swiftly to measles outbreak in Jubaland State
A surveillance system in Somalia is providing real-time early warning disease alerts to help tackle health threats such as measles outbreaks and COVID-19 cases.
12 August 2020
How has our urban world made pandemics more likely?
As more people have moved to cities, population density, human encroachment and increased global interconnectivity have contributed to the spread of infectious diseases.
11 August 2020
COVID-19 has triggered lockdown measures for billions of people around the world. As many of us struggle to adapt to the ‘new normal’, we look at the origins of quarantine measures - and how they’ve been used to contain deadly outbreaks for…
10 August 2020
How do vaccines actually work?
Vaccines prevent millions of deaths every year by harnessing the body’s immune system to create defences against future infection. But how exactly does this work?
7 August 2020
New landmark collaboration between the Serum Institute of India (SII), Gavi, the Vaccine Alliance and the Bill & Melinda Gates Foundation to accelerate manufacturing and delivery of up to 100 million doses of future safe and effective COVID-…
5 August 2020
How is Pakistan maintaining routine immunisation despite the COVID-19 pandemic?
Despite disruption to routine immunisation in Gavi-eligible countries due to COVID-19, collaborative efforts between Alliance partners and governments have made it possible to partially resume immunisation sessions in countries such as Pakistan…
4 August 2020
How creative communication strategies are helping fight COVID-19 misinformation in DRC
The misinformation surrounding COVID-19 in the Democratic Repubic of the Congo isn’t new – public health officials have seen rumours and myths circulate with Ebola. Here’s how they are tackling them.
3 August 2020
New evidence shows investments in vaccination produce even greater returns than previously thought
Analysis suggests that investments in vaccination programmes will result in US$ 0.8 trillion in returns over the next ten years.
31 July 2020
Why COVID-19 means Gavi is supporting more countries than ever before
Since 2000, Gavi has been increasing equitable access to vaccines by working with the world’s poorest countries. Yet during a pandemic, more prosperous countries are also at risk of falling through the net. How will Gavi respond?
31 July 2020
Gavi Board agrees scope of COVAX Advance Market Commitment (AMC), which aims to secure doses of COVID-19 vaccines for 92 low- and middle-income countries and economies at the same time as wealthier nations.
30 July 2020
You’ve got your antibody test result – but what does it mean?
If you test positive for COVID-19 antibodies, does that actually mean you’ve been infected?
29 July 2020
Children missing out on routine vaccinations in Somalia amid COVID-19 fears
In the recent past, 25-year-old Zahra Mohamud* had visited the Hawadle maternal and child health centre in Hargeisa regularly to have her older son Ibrahim* vaccinated against the most common childhood diseases.
28 July 2020
Gavi has helped lower-income nations narrow the vaccine coverage gap
Lower-income countries are seeing better vaccination coverage than they have had in decades, but the COVID-19 pandemic is threatening to hamper progress.
28 July 2020
Now is the Time to Pave the Way for Equitable Vaccine Distribution
When COVID-19 vaccines become available, one of the biggest challenges the global community will face is equitable distribution. This will be the single largest vaccine deployment in history.
27 July 2020
Gavi helps immunise 65 million children in 2019, though COVID-19 puts progress under pressure
New analysis of WHO/UNICEF data by Gavi, the Vaccine Alliance, shows the gap in vaccine coverage between Gavi-supported lower-income countries and wealthier countries has shrunk to record lows
24 July 2020
COVAX Facility country consultations conclude with participation from at least 136 countries
Briefings led by Gavi, CEPI and WHO over the past two weeks saw participation from at least 136 countries interested in joining a COVAX Facility aimed at guaranteeing equitable access to eventual COVID-19 vaccines.
24 July 2020
How are Gavi-supported countries maintaining routine immunisation during the pandemic?
A spotlight on Ethiopia, India, the Solomon Islands and Zambia
Governments have had to act fast to not only protect their people against COVID-19 but also to ensure protective measures like vaccination against other infectious diseases…
24 July 2020
Why the UK wants to recruit half a million people in a COVID-19 vaccine trial
The UK has just secured 90 million doses of future COVID-19 vaccines, and now it is trying to recruit volunteers for some of the biggest ever phase 3 trials to test potential vaccines.
23 July 2020
Delivering life-saving vaccines during the COVID-19 pandemic
Health workers are stopping at nothing to ensure immunizations for every child.
22 July 2020
What happens if COVID-19 mutates?
Reports of a potentially more infectious form of the coronavirus have fed fears that a "mutant” version of the virus could arise. But what does mutation actually mean and is it really a cause for concern?
21 July 2020
Should countries stop vaccinations to halt the spread of COVID-19?
It’s a devil’s choice governments have faced since the start of the pandemic, but new research could provide the answer.
20 July 2020
Can the BCG vaccine protect against COVID-19?
While researchers racing to develop a COVID-19 vaccine, the potential of the BCG vaccine – used to prevent TB – to slow the pandemic has been hotly debated. New research suggesting that the BCG could prevent severe COVID-19 disease has made…
17 July 2020
Could COVID-19 be airborne, and if so how do we protect ourselves?
Ever since the new coronavirus was identified, there has been a debate about whether it is airborne or not. Now, over 200 scientists from around the world have written to the World Health Organization urging it to consider the potential of COVID-…
16 July 2020
The vaccines success story gives us hope for the future
As the world waits for a vaccine to defeat the COVID-19 pandemic, we look back to all that vaccines have achieved for humanity.
15 July 2020
Q&A with Ola Rosling of Gapminder
The head of Gapminder, whose mission is to fight ignorance with a fact-based world view, talks with Gavi about data and COVID-19.
9 July 2020
How Technology Helps Health Workers Deliver Essential Care in Developing Countries
Living Goods saves lives by supporting digitally empowered community health workers who deliver care
8 July 2020
How do we know who is immune to COVID-19?
With surveys using antibody tests yielding disappointing results, there are growing concerns that fewer people may have already been infected with SARS-CoV-2 than was previously hoped. Yet antibodies are only part of our immune system’s response…
7 July 2020
This article is a summary of an online conversation hosted by the Gavi CSO Constituency in partnership with ACTION, Gavi, the Vaccine Alliance, RESULTS UK & Save the Children.
3 July 2020
How the COVID-19 lockdown is affecting routine immunisation
Routine immunisation has slowed in many Gavi-supported countries around the world. Here, researchers writing in The Lancet, including a Gavi scientist, look at the effect of lockdown on vaccination programmes in Karachi, Pakistan
3 July 2020
Global technology company TransferWise and a donor which asked to remain anonymous made significant financial commitments to Gavi’s Advance Market Commitment for COVID-19 Vaccines (Gavi COVAX AMC)
2 July 2020
30 June 2020: Overview of COVID-19 situation in Gavi-supported countries and Gavi’s response
Across Gavi-eligible countries, we have seen a consistent increase in cases since March 2020. Within the month of June alone, the number of cases has more than doubled, with 70 out of 73 Gavi-eligible countries reporting over 1 million confirmed…
1 July 2020
How is the pandemic impacting one of the world’s largest refugee settlements?
As of 27 June 2020, there have been 513 tests carried out in the camps, with 49 confirmed cases.
30 June 2020
First African trial of a COVID-19 vaccine
The first African clinical trial for a COVID-19 vaccine has started in South Africa, run by the University of the Witwatersrand, Johannesburg (Wits).
29 June 2020
'Global Goal: Unite for Our Future' mobilized over $6.9 billion to help the world’s most vulnerable.
26 June 2020
Ebola is officially over in North Kivu and Ituri - what can we learn for COVID-19?
On 25 June, the outbreak of Ebola in the Democratic Republic of the Congo that has raged for more than 2 years is over. What does this mean for the country and what can it teach us about ending the COVID-19 pandemic?
26 June 2020
Gavi Board calls for global access to COVID-19 vaccines
Gavi Board shows support for continued work on COVAX Facility: a global, coordinated mechanism designed to ensure rapid and equitable access to safe and efficacious COVID-19 vaccines to as broad a global population as possible
26 June 2020
What is the COVAX pillar, why do we need it and how will it work?
With more than 200 COVID-19 vaccines already in development, why do we need the Access to COVID-19 Tools Accelerator Vaccine Pillar, or COVAX Pillar?
25 June 2020
First-of-its-kind vaccine agreement helps end Ebola outbreak in eastern DRC
DRC government and WHO declare over the long-running Ebola outbreak in North Kivu, South Kivu and Ituri provinces after more than 50 days without a case.
24 June 2020
Why development aid transparency matters
At a time when economies are under pressure and government spending is under scrutiny, transparency and accountability within the development sector is more important than ever.
24 June 2020
Gavi a top performer in leading transparency index
The Vaccine Alliance ranked in the highest ‘Very good’ category out of 47 international development organisations assessed in the 2020 Aid Transparency Index
23 June 2020
Will we see a deadly second wave of COVID-19 later in the year?
Beijing, a city month’s ahead of Europe in COVID-19 terms, is now plunging back into lockdown. Many are concerned that this could be the first hint of a second wave. But is that likely and what would it look like?
22 June 2020
Seven things countries have done right in the fight against COVID-19
There has been a huge variation in how countries have responded to COVID-19. Whilst some have imposed strict lockdown measures, others have avoided tight restrictions. But what works best?
19 June 2020
16 June 2020: Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response
Seventy (of 73) Gavi-eligible countries have reported 824,259 confirmed cases and 20,641 deaths. The number of cases is increasing at an average rate of 4% from the previous day.
19 June 2020
The long-term health effects of COVID-19
Even mild symptoms from the new coronavirus can last for weeks, or disappear only to rebound with renewed intensity, so what long-term effects does the disease have on our health?
18 June 2020
As the devastating consequences of the pandemic unfold across the world, COVID-19 is making long-lasting changes in global health
17 June 2020
Is COVID-19 about to take off in Africa?
So far relatively few people in Africa have been infected by the novel coronavirus, with around 215,000 cases and 5,800 deaths in a population of 1.2 billion in the continent. But with lockdowns lifting, will cases soar?
16 June 2020
New supply agreement between UNICEF and Serum Institute of India (SII) makes pneumococcal conjugate vaccine (PCV) available at US$2.00 per dose, a 43% reduction from the Gavi price at the start of the AMC
16 June 2020
Vaccinations and COVID-19: What parents need to know
How to safely get routine vaccinations for your child during the COVID-19 pandemic
12 June 2020
When it comes to COVID-19 vaccines how can governments back a winner?
With so many COVID-19 candidate vaccines in development, and with most of them likely to fail, what’s the best way for governments to ensure they back a winner and ensure there are enough doses for everyone?
12 June 2020
A third of the world has been under some form of lockdown to tackle the COVID-19 pandemic, but has it made any difference to the number of cases and deaths?
11 June 2020
How digital tools are helping Pakistan monitor routine immunisation during the pandemic
A Gavi-supported digital immunisation registry is keeping track of vaccination activities to make sure children remain protected from other infectious diseases.
10 June 2020
5 reasons why pandemics like COVID-19 are becoming more likely
SARS, Ebola, Zika, and now COVID-19. Five reasons why disease epidemics and even pandemics are becoming increasingly common.
10 June 2020
How are Gavi's private sector partners stepping up to help fight COVID-19?
Despite the devastating economic impact this pandemic has had on businesses across the world, many are doing their part to bring this crisis to an end.
9 June 2020
Could COVID-19 ever be eradicated?
Ideally, humanity would end COVID-19 by eradicating it so there are no new cases globally even in the absence of preventive measures. However, experience with other disease eradication programmes indicates that this will be very challenging, and…
5 June 2020
How the world changed on 4 June
On 4 June, global leaders met at a virtual event to pledge support for Gavi, the Vaccine Alliance, and in the process made history by reaching new global health milestones
5 June 2020
02 June 2020: Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response
Seventy (out of 73) Gavi-eligible countries have reported 475,401 confirmed cases and 12,464 deaths. Though this number still accounts for a small proportion, about 7%, of global COVID-19 cases, this share is expected to increase given the…
4 June 2020
World leaders make historic commitments to provide equal access to vaccines for all
The Global Vaccine Summit, hosted by the UK, raises US$ 8.8 billion from 32 donor governments and 12 foundations, corporations and organisations to immunise 300m children and support the global fight against COVID-19.
4 June 2020
Gavi launches innovative financing mechanism for access to COVID-19 vaccines
Gavi Advance Market Commitment for COVID-19 Vaccines (Gavi Covax AMC) launched at Global Vaccine Summit 2020 draws strong support, early commitments from global leaders.
3 June 2020
Supporting Gavi now to build a better future
We’ve all seen the shocking projections: at least 80 million children under one are at risk of developing diseases like measles, diphtheria, and polio due to disruptions in routine immunization services because of COVID-19.
3 June 2020
Gavi provides funding to support the pandemic response in Myanmar
As one of the poorest low-income countries in South East Asia, Myanmar faces many barriers to implementing a strong and effective response to COVID-19. Gavi has now allocated over US$ 8.8 million to help ensure that Myanmar is better able to…
3 June 2020
How physical distancing, masks and eye protection reduces the spread of COVID-19
In the absence of a vaccine or treatment against the new coronavirus, measures to control its spread rely on avoiding contact with people who we are not sharing a house with. This study shows the varying effects of such preventive measures.
2 June 2020
When will it be safe to hug people again?
The physical distancing necessary to slow the spread of COVID-19 can be emotionally distressing, but since the virus is unlikely to disappear soon, when will life regain a semblance of normality?
2 June 2020
Q&A with Keller C. Rinaudo, CEO and Co-Founder of Zipline
Zipline is a California-based automated logistics company that uses autonomous drones to make on-demand, emergency deliveries of high priority products, including emergency and routine vaccines and other health products.
1 June 2020
Why is the Global Vaccine Summit so important?
The pandemic will only strengthen our commitment to vaccinate vulnerable communities. On 4 June 2020 Gavi will hold its third donor pledging conference online with the aim to raise vital funds for the next five years.
1 June 2020
How does COVID-19 compare to past pandemics?
The COVID-19 pandemic is most often compared to the H1N1 influenza pandemic of 1918, or Spanish flu, even though there have been three other major pandemics since then. So how does this coronavirus pandemic compare to those?
29 May 2020
Immunisation and COVID-19 at the 73rd World Health Assembly
Equitable access to COVID-19 vaccines was a major priority for world leaders attending the virtual meeting
29 May 2020
Why are BAME groups experiencing high rates of death from COVID-19?
Black, Asian and minority ethnic (BAME) communities in Europe and the USA are overrepresented in COVID-19 deaths. In the bid to slow and, ultimately, stop the spread of COVID-19 it is vital to understand the reasons why, in order to adequately…
28 May 2020
Vaccines for the happy few = health for none
Health is not just a human right, it is a prerequisite for development. Through its advocacy programme Global Health, Global Access, Cordaid continually stresses the importance of Health for All.
28 May 2020
COVID-19’s collateral damage could devastate low- and middle-income countries
While the number of COVID-19 cases and deaths stays relatively low across Africa, Asia and Latin America compared with the rest of the world, the economic and social consequences are likely to reverberate for decades to come.
27 May 2020
Could COVID-19 accelerate the digitisation of vaccine records?
The COVID-19 pandemic is disrupting vaccination programmes across the world, but this could provide an opportunity to hasten the move to digital record-keeping systems.
26 May 2020
What is COVID-19’s ‘R number’ and why does it matter?
Altering the ease with which the new coronavirus spreads in the population is critical to controlling the pandemic. The number of people infected by any single case - the R number – will be key. If the virus is able to infect more than one person…
26 May 2020
We are working hard to ensure that immunization services continue to be available for every child
There is no fundamental reason to stop immunization in any situation.
25 May 2020
19 May 2020: Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response
Seventy (out of 73) Gavi-eligible countries have reported 257,996 confirmed cases and 7,547 deaths. These 70 countries account for a small proportion, about 5%, of global COVID-19 cases and 2% of global deaths.
25 May 2020
Here are four ways Vietnam has managed to control COVID-19
Vietnam became one of the first countries to report a COVID-19 infection and the first to report human-to-human transmission outside of China. One hundred days later, just 270 cases had been confirmed in the country, with no deaths.
25 May 2020
How quickly can we get a COVID-19 vaccine?
It is clear that the search for COVID-19 vaccines is being fast-tracked like never before. In just a few months, we now have over 100 vaccine candidates in development, ten of which are being tested in clinical trials.
22 May 2020
Agencies call for joint effort to safely deliver routine immunization and proceed with vaccination campaigns against deadly vaccine-preventable diseases.
22 May 2020
Experts are warning that COVID-19 could become an endemic disease. What does this mean and how will it impact our response?
21 May 2020
How do you keep pregnant women safe during a pandemic?
Pregnant women can be more exposed to risk during outbreaks. With 200 million pregnant women in the world, is the global pandemic response adequate to protect them, and not just from the coronavirus?
20 May 2020
Rwanda’s efforts to strengthen its health system paying off in midst of COVID-19 pandemic
The country has made strategic investments including supply chain strengthening and technological innovation, all of which have allowed critical immunisation activities to continue during and beyond the quarantine.
19 May 2020
Is air travel risky in the age of COVID-19?
Does air travel increase your chances of getting becoming infected by the novel coronavirus and contracting COVID-19?
19 May 2020
What is contact tracing, how could it reduce the spread of COVID-19, and how could it affect me?
Controlling the pandemic demands a multi-pronged approach with other key methods like contact tracing to help stop the chain of transmission.
18 May 2020
Q&A with Jonathan Stambolis, CEO of Zenysis Technologies
Zenysis is an advanced analytics software company. Their platform helps countries harness the life-saving power of data to improve the delivery of essential health services, like childhood vaccination, and to fight infectious disease outbreaks.…
18 May 2020
The future with COVID-19: three potential scenarios
What our lives will look in the short to medium term future is uncertain, but what does seem clear is we won’t return to a pre-COVID-19 life any time soon. Here are three potential scenarios that infectious disease experts have sketched out for…
15 May 2020
Maintaining commitment to immunization in Africa through COVID-19 and beyond
The COVID-19 pandemic is putting a strain on health systems worldwide. The increasing demand on health facilities and health care workers has dramatically shifted resources from essential routine health services to COVID-19 response as countries…
15 May 2020
The poorest are most likely to die from COVID-19
Social inequity will put the poorest populations at greater risk from COVID-19
15 May 2020
How COVID-19 could be causing a rare complication in children
Initially, children seemed to be least affected by the new coronavirus. However, new evidence suggests that a small number might have a rare immune reaction to COVID-19, with some needing intensive care.
14 May 2020
How can fragile countries, like Afghanistan, respond to COVID-19?
As countries rich and poor struggle with challenges in the face of the COVID-19 pandemic, Afghanistan is taking proactive steps to overcome its own.
13 May 2020
How equipment is protecting us against COVID-19
Personal protective equipment, or PPE, such as masks and gloves are becoming part of our daily lives, but what counts as effective PPE and what doesn’t?
12 May 2020
How COVID-19 is causing a ‘hunger pandemic’
The new coronavirus has killed more than a quarter of a million people in just a few months, but the pandemic’s effect on food, housing and job insecurity will last years.
11 May 2020
Is antimicrobial resistance exacerbating the COVID-19 pandemic?
Will efforts to save lives in cases of severe COVID-19 trigger another global health crisis once the pandemic is over?
8 May 2020
5 May 2020: Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response
Sixty-nine (out of 73) Gavi-eligible countries have reported 123,129 confirmed cases and 3,941 deaths, five more countries than the 64 announced last week. These countries account for about 3% of global COVID-19 cases and deaths.
8 May 2020
How can the technology in our pockets track COVID-19?
Tracking who is infected is essential to controlling the transmission of contagious diseases. Could digital technology prove to be a game-changer for the current pandemic?
7 May 2020
10 infectious diseases that could be the next pandemic
Because of vaccination, many deadly diseases are now preventable. But we still lack vaccines for other potentially lethal diseases that could spread to become pandemics like COVID-19. Here is a list of 10 diseases to watch.
6 May 2020
COVID-19: Diagnostic testing uses, types and challenges
Even when a COVID-19 vaccine is available, testing can help pinpoint populations who should be prioritised for immunisation.
5 May 2020
Five ways coronavirus could impact the future of global health
For the global health community, the implications resulting from COVID-19 could be immense.
4 May 2020
What is an Advance Market Commitment and how could it help beat COVID-19?
How we can ensure that once a COVID-19 vaccine is available, it is accessible to everyone that needs it.
1 May 2020
28 April 2020: Overview of the COVID-19 situation in Gavi-supported countries and Gavi’s response
The COVID-19 pandemic has placed a heavy burden on global economies, health care systems and other core sectors. Gavi is helping countries reallocate their health system strengthening grants to provide fast and flexible funding for vital…
1 May 2020
Keeping routine immunisation going during COVID-19 in Indonesia
Q&A with Dr Vertando Halim, Coordinator of Expanded Programme on Immunization, Jakarta, Indonesia
29 April 2020
When is it safe to lift COVID-19 lockdown?
With so many lives and livelihoods at stake, when will the lockdowns end, and what will they look like across the world?
28 April 2020
COVID-19: Gavi and UNICEF to secure equipment and diagnostics for lower-income countries
As part of Gavi’s work supporting lower-income countries’ response to COVID-19, the Alliance is providing US$ 40 million to UNICEF to secure supplies of personal protective equipment (PPE) and diagnostics for 58 countries.
28 April 2020
A COVID-19 vaccine might be ready within 18 months. But what happens then?
The world is currently on pause, buying time while an effective vaccine against COVID-19 is developed. Already, several vaccines have entered human trials, and discussions have begun about how the most promising candidates might be manufactured…
24 April 2020
Gavi’s role in the COVID-19 response in supported countries
The COVID-19 pandemic has placed a heavy burden on global economies, healthcare systems and other core sectors. Gavi is helping countries reallocate their health system strengthening grants to provide fast and flexible funding for vital resources…
24 April 2020
Gavi and global health actors collaborate to accelerate COVID-19 technologies for all
Goal of new global collaboration is to make COVID-19 diagnostics, therapeutics and vaccines available to everybody that needs them as quickly as possible.
24 April 2020
Lessons in preparing to distribute COVID-19 vaccine
How the 2009 H1N1 influenza pandemic can help us be better prepared for distributing and administering potential COVID-19 vaccines.
21 April 2020
COVID-19 threatens weak health systems in indigenous Amazonian communities
Indigenous groups face unique health challenges. How do we mitigate these risks in our COVID response?
16 April 2020
Will wearing a mask protect me from COVID-19?
How exactly is the COVID-19 virus spread and will a mask protect me?
16 April 2020
Why a gender lens is needed for the COVID-19 response
The immediate and long-term consequences of the coronavirus pandemic are disproportionately impacting the lives of women and girls, and the most marginalised.
15 April 2020
Can routine immunisation be carried out safely during COVID-19 pandemic?
How does the benefit of stopping the spread of coronavirus weigh up against the risks from diseases such as measles?
14 April 2020
Informal workers at risk from both COVID-19 and lockdown measures
With COVID-19 spreading in low- and middle-income countries, governments have been imposing strict lockdowns that could pose an even greater threat than the virus itself.
8 April 2020
COVID-19 lessons from a frontline health worker
Interview with Emmanuel Lansana, outpatient supervisor at Monrovia’s Redemption Hospital in Liberia, about lessons learned from the Ebola outbreak that can help tackle COVID-19.
8 April 2020
How Africa has developed its scientific research capabilities
Africa is better prepared now to perform research in emerging infections than during the Ebola epidemics in West Africa.
7 April 2020
Should we wear masks against COVID-19?
Will new evidence suggesting that the virus is airborne mean we all need to wear masks?
6 April 2020
When is COVID-19 most contagious and why is self-isolation so important?
Although there are guidelines on how long people should self-isolate when infected, the data on how long people remain contagious is not yet fully understood.
3 April 2020
Coronavirus risks creating a lethal vaccine gap
Could the impact of COVID-19 on routine immunisation be an even bigger threat in low-income countries than the virus itself?
3 April 2020
COVID-19: massive impact on lower-income countries threatens more disease outbreaks
At least 13.5 million people to miss out on vaccinations due to postponement of campaigns and interruptions in routine vaccinations, with millions more likely to follow.
2 April 2020
Why human impact on the environment is leading to infections like COVID-19
As we continue to encroach on the environment and erode natural habitats, the likelihood of other diseases like COVID-19 emerging to devastate the planet are high.
1 April 2020
What kind of tests are there for COVID-19?
Large-scale testing for COVID-19 could help solve some of the mysteries surrounding the virus that are still puzzling scientists.
1 April 2020
Modelling suggests suppression strategy will save more lives from COVID-19 in poor countries
Imperial model of the spread of COVID-19 implies a suppression strategy could be most effective.
27 March 2020
What is COVID-19 and how is it spread?
With nearly 550,000 people infected, almost 25,000 dead, and hundreds of millions in lockdown across the globe, the coronavirus pandemic has brought the world to a standstill. But what do we know about COVID-19 and what can we do to fight this…
26 March 2020
Gavi applauds G20 Leaders' commitment to supporting the global effort against COVID-19
Gavi, the Vaccine Alliance applauds the commitment of the G20 Leaders chaired by Saudi Arabia “to provide immediate resources to the WHO’s…
26 March 2020
The idea of herd immunity as the solution to the COVID-19 pandemic has triggered heated debate, but what is herd immunity and how does it work?
26 March 2020
How do we stop the spread of a pandemic in a slum?
Over 1 billion lives are at risk if COVID-19 sweeps through crowded slums. How can we prepare?
25 March 2020
Why is coronavirus lockdown necessary?
With an increasing number of countries around the globe going into lockdown because of the COVID-19 pandemic, many people forced to stay home may be wondering why these measures are necessary, how long they will need to go on for and what it will…
25 March 2020
What is Gavi’s role in stopping the COVID-19 pandemic?
On the most recent issue of The Bio Report podcast, Gavi's Aurélia Nguyen discusses COVID-19 vaccine development, the role of the Vaccine Alliance in stopping the pandemic, and shares lessons learned from the 2014 Ebola outbreak that may prove…
24 March 2020
When a COVID-19 vaccine is available, how will we pay for it?
When a COVID-19 vaccine is available, how will we pay for it?
21 March 2020
Gavi Board calls for bold engagement to respond to COVID-19
With the COVID-19 pandemic already affecting 47 Gavi-supported countries, Gavi, the Vaccine Alliance has already taken new steps to help strengthen the preparedness of health systems in lower-income countries with the full support of its Board.…
19 March 2020
Research summary: How do you beat the COVID-19 pandemic in the absence of a drug or vaccine?
If COVID-19 epidemics are not controlled, 510,000 people could die in the UK and 2.2 million in the USA.
19 March 2020
With zero cases of COVID-19 in Mozambique so far, Dr Rosa Marlene, National Director of Public Health of Mozambique, discusses a potential impact that a pandemic of this magnitude could have on the country’s health system.
19 March 2020
What not to touch: how to avoid contact with the new coronavirus
We touch countless objects every day, from house keys to our mobile phones. The virus that causes COVID-19 can last for anywhere from 30 minutes to several hours in the air (in the form of aerosol droplets) before drifting down onto surfaces,…
18 March 2020
How clinical vaccine trials are speeding up in a pandemic
Clinical trials for vaccines can take 10-15 years and cost hundreds of millions of dollars, which is why pharmaceutical companies can be reluctant to start down that challenging road without a definite pay-off at the end. As the COVID-19 pandemic…
17 March 2020
How might COVID-19 play out in Africa?
Africa marks a critical juncture for the coronavirus pandemic.
13 March 2020
From travel restrictions to social distancing, what is the best way to stop a pandemic?
13 March 2020
What is an emergency vaccine stockpile and how can they prevent pandemics?
We don’t yet know how the COVID-19 pandemic will progress and how long it will take for a vaccine to be developed, but the knowledge and experience gained from past outbreaks can be applied to the global response to coronavirus.
10 March 2020
Will coronavirus herald a new era in vaccine innovation?
A vaccine against the novel coronavirus is under urgent development as the number of people infected with COVID-19 increases, a process which could also result in a new range of highly innovative vaccine technologies that ushers in a new era in…